An unavoidable question raised by our findings is whether 5-HT has a role in sexual preference in other animals. In a positron emission tomography study of humans, the response of heterosexual men to the selective serotonin reuptake inhibitor (SSRI) fluoxetine was found to be different from that of homosexual men. SSRIs inhibited compulsive sexual behaviours in homosexual and bisexual men. However, so far, none of these studies has investigated whether 5-HT has a role in sexual preference.
Despite the persistent and confusingly inaccurate reports in the national media that Ecstasy is either a "date rape drug" or a "sex drug", it is well known that for most men and women MDMA is not typically associated with actual intercourse. The two main reasons for this are that it blocks erection in a large portion of the male population and the feelings elicited in most people are more appropriate to cuddling than to sex.
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