Given the pattern of nicotine absorption described above there can be no doubt that snus is dependence forming in much the same way as other forms of tobacco consumption. There is some evidence that the dependence potential of nicotine and other psychoactive drugs is related to their speed of delivery to the brain and so one would expect snus and other non-inhaled forms of nicotine delivery to be proportionately less addictive than inhaled tobacco smoke. However, there is clear evidence that users of products with snus-like nicotine delivery profiles develop cravings and nicotine withdrawal symptoms when attempting to abstain, and find it difficult to quit. While snus probably does not produce stronger nicotine dependence than smoking, it has just minimal, if any, advantages over cigarettes or other smokeless nicotine delivery products in terms of its lower potential to induce dependence. In fact, its high nicotine delivery and hence dependence potential (relative to most other non-smoked delivery modalities) may be a critical factor enabling it to compete with the more rapidly absorbed nicotine from smoked tobacco.That review paper has Karl Fagerström's name attached, which is a plus for credibility on this point. The widely-used Fagerstrom Nicotine Dependence scale is named after him.
Phillips is the director of and Guenzel was (at the time of writing) employed by the non-profit research institute, Center for Philosophy, Health, and Policy Sciences, Inc. CPHPS is the recipient of an unrestricted gift from U.S. Smokeless Tobacco Company for support of research of Dr. Carl V. Phillips. This research was investigator-initiated. USSTC did not influence the content or see the study results before they were publicly released. Phillips and Wang have received consulting fees from USSTC related to litigation. Phillips is the recipient of an unrestricted research grant from USSTC at the University of Alberta where he will soon be employed.Kinda blows this study outta the water don't ya think?
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*The term smokeless tobacco refers to tobacco products that are not burned. Instead, most are placed in the cheek or between the lip and gum.
*Cigarette smoking increases a person’s risk of heart disease two- to fourfold. Most studies of smokeless tobacco indicate that it has no influence on heart disease risk.
*Cigarette smoking causes cancer both at sites that come in direct contact with cigarette smoke — including the mouth, nose, throat, and lungs — and at sites that don’t — including the bladder, kidney, pancreas, uterus, cervix, and stomach. Smokeless tobacco, on the other hand, has been associated with only one type of cancer — oral cancer — and the risk of oral cancer associated with the use of smokeless tobacco is less than the risk of oral cancer associated with cigarette smoking.
*The use of smokeless tobacco does not expose other people to tobacco smoke. Although the exact degree of health risk associated with exposure to environmental tobacco smoke is disputed, decreased exposure to “secondhand” smoke would certainly be welcome.
*Overall, the use of smokeless tobacco confers only about 2% of the health risks of smoking. For example, if the 400,000 people who died of smoking-related diseases had instead been using smokeless, the death toll might have
been only 8,000.
*Most people are not aware of the large difference in risks between cigarettes and smokeless tobacco. In 2005, a survey of adult U.S. smokers found that only about 11% correctly believed that smokeless tobacco products are less hazardous than cigarettes. In another survey, 82% of U.S.
smokers incorrectly believed that chewing tobacco is just as likely as cigarette smoking to cause cancer.
posted by daksya at 6:17 PM on October 11, 2006