But these so-called “iPS” cells still showed significant differences from embryonic stem cells. The three new papers report on creating iPS cells that proved virtually identical to stem cells in a variety of lab tests.
The technique used in the mouse studies could promote cancer in any patients getting therapy based on iPS cells, so researchers emphasized that a new approach that avoids that hazard would have to be developed.
Gearhart called that a major issue to be resolved. In addition, he said, scientists still must show that these cells can give rise to many cell types in the lab, as embryonic stem cells can.
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