If after 20 years you don't succeed.
April 24, 2008 1:58 AM Subscribe
Maybe it's time to give up.
posted by three blind mice (59 comments total)
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Last year's failed clinical trial
for Merck's HIV vaccine (which once appeared so promising
) led many to claim that AIDS vaccine research is in crisis. According to an unprecedented poll conducted by The Independent
most scientists involved in AIDS research believe that a vaccine against HIV is further away than ever and some have admitted that effective immunisation against the virus may never be possible.
Nearly two thirds believed that an HIV vaccine will not be developed within the next 10 years and some of them said that it may take at least 20 more years of research before a vaccine can be used to protect people either from infection or the onset of Aids.
Worse, the animal model
– which uses genetically engineered simian and human immunodeficiency viruses in a combination, known as SHIV – failed to predict what will happen when a prototype vaccine is moved from laboratory monkeys to people. "We've learnt a few important things [from the clinical trial]. We've learnt that one of the animal models, the SHIV model, really doesn't predict very well at all." Of course animal advocates have been saying this for years.