We believe that the role of methadone as an antipsychotic drug needs to be studied further; a better under-standing of the actions of opiates in schizophrenia might lead to etiologic indications, the scope of which could well extend beyond the therapeutic usefulness of opiates for dually diagnosed patients. Heroin and related opioid substances, indeed, produce specific effects on the dopaminergic pathways that are believed to be involved in the pathogenesis of schizophrenic symptomatology.
"The working hypothesis is that if psilocybin or LSD can occasion these experiences of great personal meaning and spiritual significance ... then it would allow people hopefully to face their own lives completely differently - to restructure some of the psychological angst that so often occurs concurrently with existence," said Griffiths. So by expanding their consciousness during a session on the drug, the patient is able to comprehend their thoughts and feelings from a new perspective. This can lead to a release of negative emotions that leaves them in a much more positive state of mind.
It wasn't just the happy smile that fooled them. It was the fist-sized droud that protruded like a black plastic canker from the crown of Louis Wu's head. They were dealing with a current addict, and they knew what to expect. For years the man must have had no thought but for the wire trickling current into the pleasure center of his brain. He would be near starvation from self-neglect. He was small, a foot and a half shorter than either of the invaders. ...
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