The STS-119/15A crew brought the JAXA experiment Dome Gene (Dome gene experiment) to the ISS for a 10-day incubation in the CBEF (Cell Biology Experiment Facility) within JAXA’s Saibo rack. The purpose of this experiment is to investigate the formation of amphibian A-6 cell kidney cell and A-8 liver cell lines in microgravity. On Earth, these cell cultures form a characteristic spontaneous dome shape as they grow; however, when grown on Earth in simulated microgravity conditions (such as a 3D clinostat), this dome shape is significantly reduced. These ground-based results imply that changes in gravity influence the morphogenetic properties of these cells, which has implications on liver and kidney cell development in microgravity. Images of the cell formation on-orbit were captured and sent to the ground for analysis. The samples will be returned to Earth on a future shuttle mission, and gene expression analysis will be performed via DNA array assay.
« Older "...criticism, for lack of a better word, is good.... | Linux kernel hacker Jon Master... Newer »
This thread has been archived and is closed to new comments
Buy a Shirt