Video of your immune system at work
February 6, 2010 6:58 PM   Subscribe


 
borked already, alas
posted by toodleydoodley at 7:00 PM on February 6, 2010


wow, that didn't take long.
posted by deadmessenger at 7:00 PM on February 6, 2010


We killed it.
posted by Chocolate Pickle at 7:00 PM on February 6, 2010


"This account has been suspended."
The bacteria won?
posted by Heretic at 7:00 PM on February 6, 2010


Youtube version

Saw this on reddit a couple hours ago. You're slipping, metafilter.
posted by smcameron at 7:02 PM on February 6, 2010


This is why we can't have nice things.
posted by oddman at 7:02 PM on February 6, 2010


I've lit the mod signal, to get the link changed in the post. Let's see who's sober!
posted by Brandon Blatcher at 7:06 PM on February 6, 2010


It's so weird to think that fight is likely happening inside of me right now.

Oh ten second rule, you fickle mistress.
posted by JimmyJames at 7:13 PM on February 6, 2010 [2 favorites]




OK, so the white blood cell doesn't have eyes, so it's not like it's chasing the bacterium in the same way a dog chases a cat. Moreover, the bacterium doesn't have little Speedy Gonzalez legs to run away on.

So, what's actually happening here? How are these objects moving or appearing to move? What is the mechanism at work here that explains how the white blood cell is appearing to "stay on the hunt," so to speak, like a bloodhound after a bad guy?
posted by Cool Papa Bell at 7:31 PM on February 6, 2010




What is the mechanism at work here that explains how the white blood cell is appearing to "stay on the hunt," so to speak, like a bloodhound after a bad guy?

Intelligent design.
posted by Brandon Blatcher at 7:32 PM on February 6, 2010 [1 favorite]


Tiny shoggoth in your bloodstream...
posted by Artw at 7:38 PM on February 6, 2010 [2 favorites]


Cool Papa Bell, the process is called chemotaxis. Those links should probably give you enough to go on, for starters.
posted by Quietgal at 7:39 PM on February 6, 2010 [3 favorites]


Bork! Bork! Bork!
posted by Balisong at 7:48 PM on February 6, 2010


So after I played the youtube version, one of the two videos suggested afterwards was "White Blood Cell Saves Christmas." Impressive thing, the immune system.
posted by dilettante at 7:55 PM on February 6, 2010 [1 favorite]


[Swapped out the link to the working youtube version.]
posted by cortex at 8:27 PM on February 6, 2010 [1 favorite]


I kinda felt sorry for that little guy.
posted by digsrus at 8:30 PM on February 6, 2010 [1 favorite]


what did the original link point too?
posted by delmoi at 8:44 PM on February 6, 2010


Rad.
posted by iamabot at 9:01 PM on February 6, 2010


Ba-dum, ba-dum ba-dum, ba-dum ba-dummmmmm!

Just when you thought it was safe to go back in the bloodstream.
posted by Kevin Street at 9:18 PM on February 6, 2010 [2 favorites]


Neato.

It's one thing to read about this sort of thing and try to visualize how it might go down, even with the best medical illustrations, quite another to actually see it in action. Thanks Brandon Blatcher.
posted by Zinger at 9:57 PM on February 6, 2010


Aaaand now I have a zit.
posted by dirigibleman at 10:16 PM on February 6, 2010


OMNOMNOMNOMNOMNOM

always wanted to say that...
posted by tspae at 10:45 PM on February 6, 2010


What a phage!
posted by hal_c_on at 11:13 PM on February 6, 2010 [1 favorite]


The bacteria getting eaten sorta look like diplococci - microbiology-speak for paired-up round bacterial cells. If the big phagocyte is a human PMN (polymorphonuclear leukocyte, AKA a neutrophil, our primary bacterial-gobbling shock troops), that'd make the bacterial cells likely to be either Neisseria (n. meningitides, a cause of meningitis, or n. gonorrhoeae, the cause of... guess what?) or Streptococcus pneumoniae. I'd say the latter option would be more likely.

Anybody with a less cursory knowledge of this care to weigh in?
posted by killdevil at 11:26 PM on February 6, 2010


The bacteria getting eaten sorta look like diplococci - microbiology-speak for paired-up round bacterial cells. If the big phagocyte is a human PMN (polymorphonuclear leukocyte, AKA a neutrophil, our primary bacterial-gobbling shock troops), that'd make the bacterial cells likely to be either Neisseria (n. meningitides, a cause of meningitis, or n. gonorrhoeae, the cause of... guess what?) or Streptococcus pneumoniae. I'd say the latter option would be more likely.

Anybody with a less cursory knowledge of this care to weigh in?


Do you often make parties stop?
posted by hal_c_on at 11:50 PM on February 6, 2010 [3 favorites]


hal_c_on: Do you often make parties stop?

Hell, he just got the real party started!
posted by Kattullus at 11:55 PM on February 6, 2010 [3 favorites]


Do you often make parties stop?

*bangs on the ceiling with a broom*

Turn that fucking music down or I'm calling the cops again!
posted by killdevil at 12:43 AM on February 7, 2010 [2 favorites]


A dermal dendritic cell capturing an Leishmania parasite in vivo.
[dermal DCs are a type of WBC]
posted by kisch mokusch at 1:10 AM on February 7, 2010


Go get it, boy! Go get it! Gooooood, White Cell. Gooood boy.
posted by Thorzdad at 5:43 AM on February 7, 2010 [3 favorites]


My white blood cells are apparently really, really lazy since I've had bronchitis, sinusitis and an upper respiratory infection within the last 2 months.
posted by desjardins at 6:47 AM on February 7, 2010


My white blood cells are apparently really, really lazy since I've had bronchitis, sinusitis and an upper respiratory infection within the last 2 months.

That's what happens. They get a Netflix account and bam! No productivity.
posted by Talanvor at 7:58 AM on February 7, 2010


My white blood cells are apparently really, really lazy since I've had bronchitis, sinusitis and an upper respiratory infection within the last 2 months.

As I tell my girlfriend whenever she complains that her immune system is crap because she got sick, "If it wasn't actually pretty stupendously badass, you'd already be dead."
posted by adamdschneider at 8:21 AM on February 7, 2010 [1 favorite]


If ever there was a need for Yakety Sax.

...an elegant website for a more civilized age.
posted by Evilspork at 8:48 AM on February 7, 2010


I think I see the Proteus there, off to one side... with Raquel floating outside...
posted by Guy_Inamonkeysuit at 12:51 PM on February 7, 2010 [2 favorites]


digsrus: I kinda felt sorry for that little guy.

That is only because you haven't meet one your innate immune system hasn't been able to handle


hal_c_on: What a phage!

You might be thinking of Phagocytosis, but Phage work too
posted by Blasdelb at 9:22 PM on February 7, 2010


killdevil: The bacteria getting eaten sorta look like diplococci - microbiology-speak for paired-up round bacterial cells. If the big phagocyte is a human PMN (polymorphonuclear leukocyte, AKA a neutrophil, our primary bacterial-gobbling shock troops), that'd make the bacterial cells likely to be either Neisseria (n. meningitides, a cause of meningitis, or n. gonorrhoeae, the cause of... guess what?) or Streptococcus pneumoniae. I'd say the latter option would be more likely.

The YouTube video includes a description. "It is a neutrophil chasing Staphylococcus aureus." Apparently the video was taken from a 16-mm film created in the 1950s by David Rogers, at Vanderbilt University.
posted by russilwvong at 9:55 PM on February 7, 2010


Interesting. Staph are also round, but they're supposed to be clustered up like a bunch of grapes. Ah well, I was close.
posted by killdevil at 5:27 PM on February 8, 2010


« Older Acts of Contrition   |   Cruisin’ the Fossil Freeway Newer »


This thread has been archived and is closed to new comments