Ketamine lifts depression, grows synapses, study says
August 20, 2010 7:58 AM Subscribe
posted by yoHighness (30 comments total)
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More research into into the effects of ketamine on depression published today in the journal Science [abstract]
According to the Yale researchers a single dose of Ketamine lifted depression in a matter of hours, and worked for up to one week. The study was done on rats (I was curious to find out how animals are used to study depression in humans - here's
what google came up with) .
Molecular psychiatrist Nanxin Li and colleagues also found Ketamine to have marked effects on the m-tor signaling pathway, causing synaptic growth in the rats. This is significant in comparison to current anti-depressants, which can take weeks and several doses to work, and do not promote synaptic growth.
This research gives rise to speculation about potential future drugs which could actively counter the synaptic damage caused by depression. Today in the news (google news link)
. See also: Previously
on the blue. And here's a post about Ketamine's inventor, John Lilly