"Angiogenesis is critical for tumors to grow beyond a few millimeters, and for cancer to metastasize to other parts of the body. Cancer cells use the blood vessels as conduits to other areas of the body, where a single cell can set up camp and begin forming a new tumor. Stop angiogenesis, and you stop cancer." (via) [more inside]
posted by monospace on Apr 17, 2009 - 35 comments

1999: Researchers at Wake Forest University discover an incredible oddity: a mouse resistant to many forms of cancer. The resistance is found to be inherited (Pubmed link). 2006: They show that cancer resistance can be transferred (Pubmed link) to non-resistant mice. 2008: They've found that the resistance is mediated through blood cells called granulocytes, and that some humans potentially have the same ability to resist cancer. Now they need your help. [more inside]
posted by greatgefilte on Jun 29, 2008 - 20 comments

Devil facial tumor disease has ravaged the population of Tasmanian Devils in the last decade. DFTD is a transmissible cancer, i.e. the tumor cells themselves (which differ genetically from their host animal) are the agent responsible. The disease is spread by biting and other contact, and the resulting grotesque tumors interfere with feeding and lead to starvation. Poor immune response may be partially responsible. This is actually not the only such disease: canine transmissible venereal tumor is an analogue that has been known to be contagious since the 19th century. (CTVT, however, gets a proper immune response.) [more inside]
posted by parudox on Oct 29, 2007 - 7 comments

Ivan Noble's Tumour Diary The BBC's Ivan Noble has been keeping an online diary of his fight against a malignant brain tumour. Alas, his illness is now getting the better of him, and this will be his final column. He has been, at times, an inspiration, incredibly brave and totally honest about his illness. As a former colleague, he shall also be remembered fondly. Start from the beginning, it's a must read.
posted by scaryduck on Jan 27, 2005 - 10 comments