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'It started with hair.'

Artist Heather Dewey-Hagborg uses the DNA found on things like discarded chewing gum and cigarette butts to recreate the faces of the people who left them behind.
posted by Chutzler on May 3, 2013 - 59 comments

 

Central Park Five

Remember the Central Park jogger case from 1990? Here's a (lengthy, fascinating) New York Magazine article discussing the case just around the time of the 2002 exoneration of the initial five accused, four of whom had previously confessed to the crime. 24 years after the attack, a group of filmmakers, together with the five wrongly convicted men, have created a documentary telling the tale: The Central Park Five. Criminal reform activists everywhere are hoping the story might change a few minds. Previously
posted by likeatoaster on Apr 26, 2013 - 36 comments

DNA Lab Party at 4 PM: Staph only!

Celebrate the 60th anniversary of the discovery of DNA's structure with a pictorial story behind DNA's double helix and the Rosalind Franklin papers, including correspondences and lab notes that detail some of her crystallography research, findings that laid the groundwork for Watson and Crick's later publication.
posted by Blazecock Pileon on Apr 25, 2013 - 6 comments

Researchers calculate that life began before Earth existed

Geneticists have proposed that if the evolution of life follows Moore's Law, then it predates the existence of planet Earth.
posted by Confess, Fletch on Apr 18, 2013 - 92 comments

Frændi, svifnökkvinn minn er fullur af álum.

In Iceland, with a population of around a third of a million, the danger exists of that heady one-night stand ending up as an intimate encounter between near-relatives, as nearly happened to the friend of Elin Edda. No longer, due to the launch of an android app ("Bump the app before you bump in bed") which easily tells a budding couple how related they are. [more inside]
posted by Wordshore on Apr 16, 2013 - 67 comments

Stanford Team creates biological "transistor" inside a living cell.

Have created "logic gates" they call “Boolean Integrase Logic,” or “BIL gates” for short. Original article in Science. This is same team that created DNA storage and what they are calling a "biological Internet" before.
posted by aleph on Mar 29, 2013 - 20 comments

Secret Universe

The Hidden Life Of the Cell (57:24) There is a battle playing out inside your body right now. It started billions of years ago and it is still being fought in every one of us every minute of every day. It is the story of a viral infection - the battle for the cell. This film reveals the exquisite machinery of the human cell system from within the inner world of the cell itself - from the frenetic membrane surface that acts as a security system for everything passing in and out of the cell, the dynamic highways that transport cargo across the cell and the remarkable turbines that power the whole cellular world to the amazing nucleus housing DNA and the construction of thousands of different proteins all with unique tasks. The virus intends to commandeer this system to one selfish end: to make more viruses. And they will stop at nothing to achieve their goal. Exploring the very latest ideas about the evolution of life on earth and the bio-chemical processes at the heart of every one of us, and revealing a world smaller than it is possible to comprehend, in a story large enough to fill the biggest imaginations.
You may be familiar with molecular movies from my two previous megaposts collecting them, but this extended documentary uses original animation that is collected into a coherent educational narrative and is just so fucking gorgeous. Enjoy.
[more inside]
posted by Blasdelb on Mar 24, 2013 - 20 comments

Bigfoot DNA as mysterious as the elusive cryptid

November 24, 2012: analysis of extensive DNA sequencing of 'a novel hominin hybrid species, commonly called “Bigfoot” or “Sasquatch” ... suggests that the legendary Sasquatch is a human relative that arose approximately 15,000 years ago as a hybrid cross of modern Homo sapiens with an unknown primate species.' The press release claimed that the research was "currently under peer-review," except that no scientific journal would publish the research, until now: DeNovo, an open access scientific journal. But DeNovo isn't really open access, as it costs $30 to view the article, the paper itself is brand new, the domain was recently purchased, and the website features generic stock photos. Ars Technica digs deeper, summarizing some of the "open access" article, and providing a link to a particularly insightful clip on YouTube, with an odd water mark. [more inside]
posted by filthy light thief on Feb 18, 2013 - 68 comments

Polio Eradication

How the CIA Is Hurting the Fight Against Polio.
posted by homunculus on Feb 11, 2013 - 63 comments

Data Storage in DNA Becomes a Reality

"The researchers began with the computer files from some notable cultural highlights: an audio recording of MLK Jr.’s 1963 “I Have a Dream” speech, all 154 of Shakespeare’s sonnets, and, appropriately, a copy of Watson and Crick’s original research paper describing DNA’s double helix structure. On a hard drive, these files are stored as a series of zeros and ones. The researchers worked out a system to translate the binary code into one with four characters instead: A, C, G and T. They used this genetic code to synthesize actual strands of DNA with the content embedded in its very structure. The ouput was actually pretty unimpressive: just a smidgeon of stuff barely visible at the bottom of a test tube. The wow factor arose when they reversed the process. The researchers sequenced the genome of the data-laden DNA and translated it back into zeros and ones. The result was a re-creation of the original content without a single error, according to the results published in Nature on Wednesday."
posted by SpacemanStix on Jan 26, 2013 - 37 comments

Bring me more genomes

"If the history of public health has until now been embodied by the map—as in British physician John Snow’s famous map, which allowed him to curb the London cholera outbreak of 1854 and to found, in doing so, the modern field of epidemiology—Snitkin was embarking on a new kind of epidemiology: one founded on the phylogenetic tree." Writing for Wired, Carl Zimmer describes how Evan Snitkin and Julie Segre used genome sequencing to halt a bacterial outbreak at the National Institute of Health's Clinical Center. (via The Feature)
posted by catlet on Jan 26, 2013 - 9 comments

Soon, you too can become a flash drive.

Scientists at the European Bioinformatics Institute successfully encoded several different file formats onto strands of synthetic DNA, which were then sent to an American lab and sequenced to extract the data. Selections included Shakespeare, audio of Dr. Martin Luther King, and photos of their lab. If the idea sounds vaguely familiar, you've probably been reading Dresden Codak.
posted by BZArcher on Jan 24, 2013 - 23 comments

Pictures of CATs

Scientists snap a picture of DNA’s double helix for the very first time
posted by cthuljew on Dec 1, 2012 - 33 comments

DNA data storage

Just think about it for a moment: One gram of DNA can store 700 terabytes of data. That’s 14,000 50-gigabyte Blu-ray discs… in a droplet of DNA that would fit on the tip of your pinky. To store the same kind of data on hard drives — the densest storage medium in use today — you’d need 233 3TB drives, weighing a total of 151 kilos. In Church and Kosuri’s case, they have successfully stored around 700 kilobytes of data in DNA — Church’s latest book, in fact — and proceeded to make 70 billion copies (which they claim, jokingly, makes it the best-selling book of all time!) totaling 44 petabytes of data stored. [more inside]
posted by latkes on Nov 25, 2012 - 72 comments

"The Double Helix has more in common with Truman Capote's In Cold Blood than, say, The Decline and Fall of the Roman Empire."

"The Turn of the Screw: James Watson on The Double Helix and his changing view of Rosalind Franklin": Maggie Koerth-Baker's brief interview with Watson, co-discoverer of the structure of DNA, about his "infamous" treatment of Franklin in his book The Double Helix, on the occasion of the publication of an annotated and illustrated edition of the same.
posted by ocherdraco on Nov 8, 2012 - 32 comments

Hacking the President’s DNA

Hacking the President’s DNA. "The U.S. government is surreptitiously collecting the DNA of world leaders, and is reportedly protecting that of Barack Obama. Decoded, these genetic blueprints could provide compromising information. In the not-too-distant future, they may provide something more as well—the basis for the creation of personalized bioweapons that could take down a president and leave no trace."
posted by homunculus on Oct 26, 2012 - 45 comments

Mad scientist in your own basement?

The Genome Compiler is an IDE for DNA projects for all you DIYbio enthusiasts. Previously. Previously.
posted by lipsum on Oct 17, 2012 - 24 comments

Eating the plate instead of the food

With the possible exception of the Nobel awards, physicists seem to get all the press these days, whether they're doing quantum level work at the LHC, or cosmology via the latest satellite data. Biologists, not so much. It's too bad, because Richard Lenski is running one of the great evolutionary experiments of our time, and it's producing interesting results. [more inside]
posted by CheeseDigestsAll on Oct 8, 2012 - 34 comments

Plurality

Plurality ... in 2023, the Grid knows who you are and where you go at all times. A short near future sci-fi movie (15 min).
posted by crunchland on Oct 4, 2012 - 23 comments

When worker honeybees change jobs their DNA changes.

When worker honeybees change jobs their DNA changes. The DNA change seems reversible and epigenetic in nature.
posted by aleph on Sep 18, 2012 - 28 comments

ENCODE: the Encyclopedia of DNA Elements

In 2001, we learned the sequence of our genome; now, we have amassed a vast amount of knowledge about what those sequences actually do. Yesterday, the data from the ENCODE project went live. [more inside]
posted by Westringia F. on Sep 6, 2012 - 32 comments

"Abused people go one or two ways: They either self-destruct or make a difference, you feel me? I’m gonna make a difference."

'In 2002, five years before journalist Chauncey Bailey was murdered by members of Your Black Muslim Bakery, (Previously) a woman identified only as Jane Doe No. 1 stepped forward to report decades of sexual abuse, welfare fraud and violence by the bakery's leader, Yusuf Bey Sr. She was prepared to hand over to Oakland police DNA from her three children -- evidence that Bey had impregnated her, the first time when she was 12. This was a risky move, but the woman had powerful motivation: her daughter, then 18, had alerted her that Bey was trying to abuse her -- his own child. Now, Jane Doe No. 1 has decided she no longer wants to be nameless. Her name is Kowana Banks and she is the first of Bey's victims to speak publicly.' Video interview. Transcript. (Via) This post recounts experiences of rape and sexual abuse. Topics may be disturbing to some readers. [more inside]
posted by zarq on Aug 9, 2012 - 8 comments

Hunting down my son's killer

Matt Might, computer science professor, has a son with a new genetic condition. This is the story of how they figured this out. Matt Might, perhaps best known for the illustrated guide to a PhD, tells the wrenching tale of their son's terrible medical condition and how they've worked to figure out what is going on with him.
posted by k8t on May 29, 2012 - 38 comments

XNA - more fun than Sea Monkeys...

XNA
posted by brando_calrissian on Apr 19, 2012 - 16 comments

Once extracted, what you do with it is up to you...

"Ever wish you could see the strands of genetic material that make you...you?" NOVA shows you how to extract your DNA with this do-it-yourself tutorial using household items. [via]
posted by quin on Mar 8, 2012 - 38 comments

Entire genome of extinct human decoded from fossil

Entire genome of extinct human decoded from fossil
posted by Meatbomb on Feb 7, 2012 - 32 comments

"Mr. Hammond, after careful consideration, I've decided not to endorse your park."

"God creates dinosaurs. God destroys dinosaurs. God creates man. Man destroys God. Man creates dinosaurs." [Discovery.com] Within five years, a woolly mammoth will likely be cloned, according to scientists who have just recovered well-preserved bone marrow in a mammoth thigh bone. Japan's Kyodo News first reported the find. You can see photos of the thigh bone at this Kyodo page.
posted by Fizz on Dec 6, 2011 - 111 comments

for the budding Bene Tleilax

The quest for the $500 home molecular biology laboratory Molecular diagnostics and molecular biology in general are becoming more pervasive every day in a range of applications. For some time there have been attempts to build an affordable diy machine to explore this fascinating science. OpenPCR (polymerase chain reaction) received quite a bit of publicity with their $599 system. Each of these have had problems and were not quite suitable for students. Here is an attempt to get the price even lower and to simply the construction process. Previously on Metafilter
posted by 2manyusernames on Dec 5, 2011 - 27 comments

The Black Death Revealed

DNA from the teeth of medival corpses confirm that the Black Death was caused by Yersinia pestis. [more inside]
posted by Bulgaroktonos on Oct 12, 2011 - 38 comments

Out of Africa

Australian Aboriginals were the first explorers, DNA research shows [more inside]
posted by mumimor on Sep 22, 2011 - 33 comments

Building Blocks Of DNA Come From Space

NASA Proves Building Blocks Of DNA Come From Space. "NASA researchers studying meteorites have found that they contain several of the components needed to make DNA on Earth. The discovery provides support for the idea that the building blocks for DNA were likely created in space, and carried to Earth on objects, like meteorites, that crashed into the planet’s surface. According to the theory, the ready-made DNA parts could have then assembled under Earth’s early conditions to create the first DNA."
posted by homunculus on Aug 9, 2011 - 44 comments

Worldwide respect. Awe. A healthy fear.

A Simple Plan to Fix the American Political System Using Common Sense and a Little Dinosaur DNA by Tim Siedell.
posted by blue_beetle on Jul 26, 2011 - 17 comments

The continued tragedy of Argentina's Dirty War

Ernestina Herrera de Noble heads up The Clarin Group and the Clarin newspaper (in Spanish), the largest in Argentina. She is the mother of two adopted children, Felipe and Marcela, heirs to the Clarin Group fortune. She has been a controversial figure for much of her life. Currently, her paper stands in staunch opposition to the administration of President Cristina Kirchner, who in 2009 successfully pushed through legislation forcing the Clarin group to sell off some of its holdings. President Kirchner recently announced she will be seeking a second term. However, Mrs. Herrera de Noble's legacy will probably rest on the suit brought against her by the Grandmothers of the Plaza del Mayo, forcing her children to submit DNA samples to ascertain whether they are the children of detainees killed by the military during Argentina’s “Dirty War”. The siblings and their mother have fought to avoid DNA testing, claiming it is a violation of their privacy, but there are families who claim that Felipe and Marcela are the natural born children of women pregnant when they were detained and subsequently disappeared. Ernestina insists that the adoptions were “legal”, and her children stand by her side. If a genetic link is proven to former detainees, Mrs. Herrera de Noble may face a criminal investigation.
posted by msali on Jun 22, 2011 - 30 comments

The Lazarus File

The Lazarus File. "In 1986, a young nurse named Sherri Rasmussen was murdered in Los Angeles. Police pinned down no suspects, and the case gradually went cold. It took 23 years—and revolutionary breakthroughs in forensic science­—before LAPD detectives could finally assemble the pieces of the puzzle. When they did, they found themselves facing one of the unlikeliest murder suspects in the city’s history." [more inside]
posted by zarq on May 14, 2011 - 60 comments

Unfit counsel

"This conflict of interest hits at the heart of the attorney-client relationship." Robert Caulley has served 14 years of a life sentence for the murder of his parents, a crime he says he didn't commit. Some hope that unknown DNA found on a gun at the crime scene will prove his innocence, citing similar exonerations in other high-profile Ohio cases, but so far Caulley's attempts to revisit his case with further DNA testing have failed. But look, Caulley already had his day in court with his lawyer by his side, doing everything possible to clear him, right? So he thought -- until he learned that his defense attorney was sleeping with his wife during his trial.
posted by escabeche on Apr 21, 2011 - 20 comments

master of information

The New Biology - Eric Schadt's quest to upend molecular biology and open source it. (via)
posted by kliuless on Apr 9, 2011 - 35 comments

"Genetic engineers don't make new genes, they rearrange existing ones."

The Xenotext Experiment is Christian Bök's [Previously],"nine-year long attempt to create an example of “living poetry.” I have been striving to write a short verse about language and genetics, whereupon I use a “chemical alphabet” to translate this poem into a sequence of DNA for subsequent implantation into the genome of a bacterium (in this case, a microbe called Deinococcus radiodurans—an extremophile, capable of surviving, without mutation, in even the most hostile milieus, including the vacuum of outer space)." [Via] [more inside]
posted by Fizz on Apr 4, 2011 - 25 comments

It's life, Jim, but not as we know it

Could the three established domains of life - eukaryotes, bacteria and archaea - be joined by a fourth?
posted by Artw on Mar 25, 2011 - 53 comments

Conviction

Betty Anne Waters's brother Kenny was sent to prison for first degree murder and armed robbery in 1982. Over the next 16 years, Betty Anne got her GED, college degree, and law degree, all in an effort to prove Kenny was innocent. With the assistance of the Innocence Project, Betty Anne was able to use DNA evidence to show Kenny was innocent. [more inside]
posted by reenum on Mar 24, 2011 - 28 comments

Cell division = copyright infringement?

“To live, to err, to fall, to triumph, to recreate life out of life.” Craig Venter created synthetic life and inscribed this quote from James Joyce into its genome. Now he has been threatened with a suit for copyright infringement by the very litigious James Joyce estate.
posted by caddis on Mar 20, 2011 - 32 comments

Twenty-eight years and eight months

The Someone You're Not: "Our packed prisons are starting to disgorge hundreds of mostly African-American men who, over the last few decades, we wrongly convicted of violent crimes. This is what it's like to spend nearly thirty years in prison for something you didn't do. This is what it's like to spend nearly thirty years as someone you aren't. And for Ray Towler, this is what it's like to be free." Via. [more inside]
posted by zarq on Feb 25, 2011 - 18 comments

Canine CODIS

Poo Prints: DNA Profiling for Pets; "... designed to help communities enforce their pooper scooper rules and give the pet owner tools that help them build a better relationship with their dog." [more inside]
posted by bwg on Jan 3, 2011 - 73 comments

Good News for Pregnant Needlephobes....

Invasive amniocentesis and chorionic villi sampling (CVS) tests are commonly used to determine the chromosomal, structural and genetic abnormalities in fetuses. But could they eventually become obsolete? A Chinese study has found that a complete copy of the fetal genome exists in the mother's blood, suggesting many prenatal diagnoses could potentially be performed noninvasively. [more inside]
posted by zarq on Dec 8, 2010 - 30 comments

truth hangs by a hair

A DNA test has proven that a man was executed for murder by the State of Texas on the basis of false forensic evidence. [more inside]
posted by hat on Nov 12, 2010 - 99 comments

This Is Another Fine Mist You've Gotten Me Into

"The mist — visible only under ultraviolet light — carries DNA markers particular to the location, enabling the police to match the burglar with the place burgled. Now, a sign on the front door of the McDonald’s prominently warns potential thieves of the spray’s presence: 'You Steal, You’re Marked.'"
posted by Scoop on Oct 19, 2010 - 65 comments

The reanimated zombie gene

Noncoding "junk" DNA is a signature part of the genomes of eukaryotes. Scientists have now identified a case of such DNA causing a genetic disease (Facioscapulohumeral Muscular Dystrophy) in certain genetic backgrounds by stabilizing the messenger RNA of a gene.
posted by jjray on Aug 19, 2010 - 20 comments

iBOL iWish there were an app for that already

What is dna barcoding?

tl;Linnaeus
tl;Edward Norton [more inside]
posted by infinite intimation on Jul 14, 2010 - 34 comments

Queer Science

Less than two weeks after a controversial paper came to light advocating the pre-natal treatment of some female fetuses with a hormone to make their behavior more stereotypically female (previously discussed here) comes news of actual animal research on causing the opposite inclination. By knocking out the fucose mutarotase gene, scientists in South Korea have apparently created "Lesbian mice" who prefer other female mice and who resist the attempts of male mice to mate with them. Article abstract, and coverage by The Telegraph.
posted by Asparagirl on Jul 9, 2010 - 19 comments

"UC Berkeley offer to test DNA of incoming students sparks debate"

LA Times: "When UC Berkeley officials came up with the idea of asking all new students to volunteer a DNA swab as part of an unusual fall orientation program, they expected to stimulate discussion. They weren't quite prepared for how much."
Inside Higher Ed: "Unwinding Berkeley's DNA Test"
posted by andoatnp on Jun 4, 2010 - 29 comments

Venter creates spiraling coils of self-replicating DNA.

"The ability to design and create new forms of life marks a turning-point in the history of our species and our planet." - Freeman Dyson, on the J.C. Venter Institute's creation of a cell controlled by a synthetic genome. We are now in the business of engineering life.
posted by BoatMeme on May 20, 2010 - 62 comments

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