The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
Coding Like a Girl - sailor mercury at Medium:
"Apparently, presenting as feminine makes you look like a beginner. It is very frustrating that I will either look like not a programmer or look like a permanent beginner because I have programmed since age 8. I have basically always wanted to be a programmer. I received undergrad and grad degrees from MIT. I’ve worked as a visiting researcher in Honda’s humanoid robotics division on machine learning algorithms for ASIMO.[more inside]
"I don’t think that any of these things make me a better programmer; I list them because I am pretty sure that if i were a white man with these credentials or even less than these credentials no one would doubt my programmer status."
The annual James Dyson Award is open to current and recent design engineering students. The winner this year is James Roberts with his inflatable incubator MOM. The device costs around £250 compared to £30,000 for modern incubators and could prevent up to 75% of fatalities in premature birth cases in the developing world.
The Ecce Robot is an attempt to create a robot that not only mimics human movement and form, but also musculature and body construction. There are more videos at the project's site. [more inside]
If you live in the Boston area and would like to attend science, technology, math, or engineering lectures, you'll find Fred Hapgood's exhaustive and continually-updated list of Selected Lectures on Science and Engineering in the Boston Area very useful. (Here's his list of sources.) Perhaps you know of a list like this for lectures in your locality or field of preference?
Norbert Wiener: The Eccentric Genius Whose Time May Have Finally Come (Again) - "The most direct reason for Wiener's fall to relative obscurity was the breakthrough of a young mathematician and engineer named Claude Shannon." [more inside]
HP scaling memristor and photonic computing: "the device is essentially remembering 1s or 0s depending on which state it is in, multiplying its storage capacity. HP can build these chips with traditional semiconductor equipment and expects to be able to pack unprecedented amounts of memory—enough to store huge databases of pictures, files, and data—into a computer. In theory, that would remove the need for a conventional slow disk/fast memory system. With the Machine's main chips sitting on motherboards right next to the memristors, they can access any needed information almost instantly..." [more inside]
Following on the heels of Phonebloks, a Google/Motorola formed a design group called Project Ara. The Verge recently interviewed Paul Eremenko, the project lead, about progress made towards modularization of mobile phone components, overcoming engineering issues, and the group assigning itself an ambitious timetable to succeed in delivering a sellable product within two years, or disbanding.
How Airbus is Debugging the A350-XWB. Jeff Wise, writing in Bloomberg Business Week, describes the 18-month testing process for the new Airbus A350-XWB passenger jet. One page version (printer format). And a bonus media offering: a somewhat functional online 3D flight simulator. [more inside]
The Columbia Journalism Review interviews Evgeny Morozov: Evgeny vs. the internet
The entire Morozov aesthetic is in this sentence: the venom, the derision, the reverse jujitsu of his opponents’ sanctimony, the bald accusation that all the talk about a new age of human flourishing is nothing but an attempt to vamp the speaker’s consulting business. Tech enthusiasts channel hope. Tech skeptics channel worry. Morozov channels anger, and this can be a very satisfying emotion to anyone unconvinced that everything is getting better. Leon Wieseltier, who has published some of Morozov’s most acid criticism at The New Republic, compares him to the ferocious jazz musician Charles Mingus, who once responded to an interviewer who accused him of “hollerin’ ” by saying, “I feel like hollerin’.” I asked Morozov if he considers his Twitter feed, which spews a constant stream of invective and absurdist satire, to be performative. This was a bit like asking Mingus if he considers jazz performative. “Absolutely,” he said. “I consider it art.”[more inside]
Recently Emily Graslie, of the fantastic natural history tumblr and youtube series TheBrainScoop, was asked a question about whether she had personally experienced sexism in her field. Her response is fucking amazing.
Inside is her goldmine of awesome female science educators online with channels that focus on Science Technology Engineering and Math. My work day is fucked.[more inside]
How NASA brought the monstrous F-1 "moon rocket" engine back to life - "The story of young engineers who resurrected an engine nearly twice their age." [more inside]
Meet Bertha, the world's largest underground tunnel boring machine that will soon begin digging a controversial roadway underneath downtown Seattle, similar to Boston's Big Dig
The Forces Of The Next 30 Years - SF author and Mefi's Own Charles Stross talks to students at Olin College about sci-fi, fiction, speculation, the limits of computation, thermodynamics, Moore's Law, the history of travel, employment, automation, free trade, demographics, the developing world, privacy, and climate change in trying to answer the question What Does The World Of 2043 Look Like? (Youtube 56:43)
Surely you've heard of the physicist Maxwell, but what about Oliver Heaviside? Oliver Heaviside: A first-rate oddity.
New research can detect five different emotions with 81 percent accuracy. [Additional project information].
Alan Cooper and the Goal Directed Design Process The heart of the problem, he concludes, is that the people responsible for developing software products don’t know precisely what constitutes a good product. It follows that they also do not know what processes lead to a good product. In short, they are operating by trial and error, with outcomes like customer satisfaction achieved by little more than blind luck. By Hugh Dubberly, first published AIGA GAIN Journal, 2001
The EEV Blog is an "off-the-cuff" video blog that deals with pretty much anything related to Electrical Engineering, known for its very knowledgeable and enthusiastic host.
When it comes to railways, the British are famous for their colonial legacy of one of the world's most extensive railway networks built across then British India but their lesser known and far grander vision was the Cape to Cairo railway network intended to stretch across the sea of colonial pink on the African continent. Left incomplete due to politics and geography, most of it is still almost as it was built in its day. [more inside]
In February 2011, every teacher in Providence, Rhode Island was pink slipped. Not all 1,926 of them got fired, of course, but with the district facing a $40 million deficit, anything is possible. The district says it needs flexibility, just in case. Every school district in the United States faces its own version of what’s happening in Providence. However, “IMAGINATION: Creating the Future of Education and Work” is focused not on how we got here but rather how we can move forward from here immediately even as the education system continues to struggle. [more inside]
Cogitate - Manipulate LEGO TECHNIC gears, beams, conveyor belts and motors to complete the ten pre-built puzzles or create your own levels. [In my case - Then watch them crash in a heap when you test them.]
Dorkbot is a "monthly meeting of artists (sound/image/movement/whatever), designers, engineers, students, scientists, and other interested parties who are involved in the creative use of electricity." Started in NYC in 2000 by Douglas Repetto, Director of Research at the Columbia University Computer Music Center as well as one of Wired's 10 Sexiest Geeks, there are now dozens all over the world. Past presenters have been featured here on the blue. For instance Jeff Han presented his multi-touch interface at dorkbot-nyc in April of 2006. Miru Kim presented her naked city spleen at dorkbot-nyc in October of 2006. Bummed that there's not one in your own city? Start your own! [more inside]
The coming memristor revolution in electronics and how it works. The newly created memristor, only the fourth fundamental fundamental type of passive circuit element, has the promise of computing advances both prosaic (faster, cheaper and "bigger" flash drives) and momentous (relatively effortless mimicry of brain cells and their activity). This is the story of the memristor's genesis, told by R. Stanley Williams, the leader of the team that created the device. [more inside]
Andy Grove on Our Electric Future - "Energy independence [viz.] is the wrong goal. Here is a plan Americans can stick to." Perhaps some infrastructure spending1,2 is in order? [etc., &c., cf.] [more inside]
Where the Engineers Are - "To guide education policy and maintain its innovation leadership, the United States must acquire an accurate understanding of the quantity and quality of engineering graduates in India and China."
Resources for lighting designers and enthusiasts: The Lighting Wiki; [extensive] Glossary of Lighting Terminology (and another); Lighting Design Resources (inc. "Fun with Light"; and Professional Lighting Resources.
Necessity Is the Mother of Invention. (NY Times, reg. req.) Amy Smith teaches MIT students about the politics of delivering technology to poor nations and the nitty-gritty of mechanical engineering and helped start the IDEAS competition; she herself designed (among other things) a screenless hammer mill suited to third-world conditions and using "materials available to a blacksmith in Senegal."
Smith's entire life is like one of her inventions, portable and off the grid. At 41, she has no kids, no car, no retirement plan and no desire for a Ph.D. Her official title: instructor. ''I'm doing exactly what I want to be doing. Why would I spend six years to get a Ph.D. to be in the position I'm in now, but with a title after my name? M.I.T. loves that I'm doing this work. The support is there. So I don't worry.''...A rare optimistic story for these downbeat times.
Likewise, the inventors who most inspire her will never strike it rich. ''There are geniuses in Africa, but they're not getting the press,'' she says. She gushes about Mohammed Bah Abba, a Nigerian teacher who came up with the pot-within-a-pot system. With nothing more than a big terra-cotta bowl, a little pot, some sand and water, Abba created a refrigerator -- the rig uses evaporation rather than electricity to keep vegetables cool. Innovations that target the poorest of the poor don't have to be complicated to make a big difference. The best solution is sometimes the most obvious.
Seven hot technologies that we'll soon see on the market, according to MIT's Tech Review magazine. The spam blocker sounds like it might work. But the babelfish?
More than meets the eye. Next stop, Cybertron!