MetaFilter posts tagged with Genetic

We walk by faith, not by sight

Joe Beese — Tue, 21 Apr 2009 14:11:48 -0800

It is apparent to me that Faith does have a brain, despite what the doctors have said. Even though it is generally believed that anencephalic babies are blind, deaf, and cannot feel touch or think... I don't believe that. Not at all. So little is known about the human brain and the only one who really knows what's going on is God. I truly believe that Faith can think and can feel my touch and hear my voice. I can't prove it but I feel like I just know. [images may be disturbing]

A New Theory Of Mental Disorders

grumblebee — Tue, 11 Nov 2008 11:49:06 -0800

"Their idea is, in broad outline, straightforward. Dr. Crespi and Dr. Badcock propose that an evolutionary tug of war between genes from the father’s sperm and the mother’s egg can, in effect, tip brain development in one of two ways. A strong bias toward the father pushes a developing brain along the autistic spectrum, toward a fascination with objects, patterns, mechanical systems, at the expense of social development. A bias toward the mother moves the growing brain along what the researchers call the psychotic spectrum, toward hypersensitivity to mood, their own and others’. This, according to the theory, increases a child’s risk of developing schizophrenia later on, as well as mood problems like bipolar disorder and depression."

Please don't tell William Gibson this exists.

Slap*Happy — Fri, 05 Sep 2008 22:26:52 -0800

I know what you're thinking. What could be better than a below-low-budget sci-fi/horror hypersexualized movie based off of a musical, with a playwright who also decided to star in both stage and screen adaptations? Well, then, what if we up the ante! It's also a socially-conscious cyberpunk movie musical, written, directed, scored and costumed by people in 2008 who have decided that 1996 is as far as the future goes, thanks... so it's also a goth/raver socially conscious cyberpunk movie musical, complete with blue-streaked hair, muppet-fur and clunky vinyl boots! No? We need to aim higher to do better? Well, here comes the kicker, the one element that will immortalize this film: Starring Paris Hilton. Singing. In S&M gear. And a wig. Doing drugs. Lo, I bring you REPO! The Genetic Opera! (The film.) NSFW or self respect.

The world’s worst disease

Bora Horza Gobuchul — Thu, 05 Jun 2008 14:29:59 -0800

While many ailments are considered terrifying, Lesch-Nyhan is the stuff of nightmares. An extremely rare genetic neurological disorder with no cure, it often compels its victims to self-mutilate, even when they understand that doing so causes them harm. Richard Preston used Lesch-Nyhan as a plot device in his best-selling thriller The Cobra Event, and went on to write a fascinating article about the disease, its sufferers, and its implications for human behavior in the New Yorker. [PDF]. Inspired by this question in the green and ericb’s follow-up answer. Related articles on PubMed. Previous mentions of Lesch-Nyhan on the blue. I’ve described Lesch-Nyhan as a talking point in classroom debates over the ethical implications of genetic analysis and intervention: it is the quietest and saddest moment I have in a classroom.

"How wonderfully Gothic!"

msalt — Fri, 23 May 2008 18:39:02 -0800

Heated controversy over cousin marriages in Britain. The Guardian argues it's fine, legal in the UK for centuries, done by Darwin, HG Wells and Queen Victoria; and a 2002 study (prev) found little increased risk. But in Bradford, England, where half of babies born are to ethnically Pakistani parents, cousin marriage is very common -- as high as 70% in that community. Bradford, with 1% of British population, has 70 youths with terminal disorders which lead to dementia-type illnesses – eight per cent of the UK total. Should the government ban cousin marriage? Encourage genetic testing? Or keep its mouth shut? The fact that consanguineous marriages are most common among Muslim Pakistani immigrants makes the discussion more contentious. The Environment Minister Woolas was rebuked in February for expressing concerns intemperately. According to a 2005 BBC investigation, British Pakistanis account for 3.4% of all births but have 30% of all British children with recessive disorders, and the Birmingham Primary Care Trust estimates that one in ten of all children born to first cousin marriages in Birmingham's large Pakistani community either dies in infancy or goes on to suffer serious disability as a result of recessive genetic disorders. The 2002 study may have underestimated risk by ignoring the compounding effect -- i.e. the risk for two cousins whose family hasn't previously mixed may be very different from that in an extended family (e.g. the Windsors) who mix repeatedly for generations. And professor Alan Bittles, a leading expert, notes that within some communities even non-cousin marriages carry higher risks of these rare genetic disorders because those involved are from the same "biraderi" or clan. Better data is on the way from the Born in Bradford study (wiki), now a year old. It's the largest children's health study in the world, aiming to track all babies born in the city from autumn 2006 to early 2008 (approx. 10,000 children) until age 16. They have found 150 different genetic disorders among those children, where 20-30 would be expected in a comparable city.

Consider the pixies....

dersins — Mon, 03 Dec 2007 09:11:35 -0800

Williams syndrome is a rare genetic disorder characterized by distinctively "elfin" facial features, an uncanny ability to socialize with strangers, and, often, enhanced musical abilities.

The Perfect Marriage of Great Science and Great Hair

hermitosis — Wed, 07 Nov 2007 07:24:19 -0800

A 2007 Nobel Prize-winning breakthrough in genetics may hold the key to eliminating Trichotillomania: the gene Hoxb8 governs grooming behavior in mammals.

How to Sequence a Genome

McLir — Thu, 23 Aug 2007 17:16:53 -0800

How to Sequence a Genome [Flash. H/T to Jay]. Visualization of the process of genetic sequencing. Posted on the Nova website in conjunction with their show, Cracking the Code of Life, hosted by Robert Krulwich [Wiki].

FizerPharm: Flexible ethics for a complex world

maudlin — Sun, 24 Dec 2006 09:20:26 -0800

Peter Watts on Vampire Domestication (embedded Flash video, must click to start). The mythical corporation FizerPharm ("Trust. Profit. Deniability.") share their detailed research into the evolution and possible commercial applications of Homo sapiens whedonum. You will learn: How and why the "crucifix glitch" came about. Why you should run from a blushing vampire. How many kilograms of human are needed to make one kilogram of vampire. How vampires resemble two year old humans, domestic shorthaired cats, and lungfish. And why "survival of the fittest" should be reconceptualized as "survival of the least inadequate". [more inside]

The Sole Survivor

cenoxo — Wed, 30 Aug 2006 01:00:56 -0800

The Sole Survivor — Allen Boyd [Real Player interview] is the sixth and last surviving member of his family: the other five committed suicide. Is suicide genetic?

Creepy, creepy, creepy.

boo_radley — Sat, 17 Jun 2006 16:30:54 -0800

Say Hello to the all New Genpets from Bio.Genica! The Genpets are Pre-Packaged, Bioengineered pets implemented today!

What did one ghost say to the other?

MetaMonkey — Wed, 03 May 2006 12:31:30 -0800

Get A-Life - an interesting read on artificial life and evolutionary computation, from the game of life (playable applet), through core wars, tierra and on to genetic programming. This approach has recently borne fruit to genetic programming pioneer and inventor of the scratchcard, John Koza, who last year patented his invention machine, actually a 1000 machine beowulf cluster running his software, which has itself created several inventions which have been granted patents. [See also: BBC Biotopia artificial life experiment, another odd BBC evolution game, Artificial Life Possibilities: A Star Trek Perspective]

The Future of Food

piscatorius — Wed, 29 Mar 2006 14:58:01 -0800

Everyone knows big business does things better than nature, god and everything else. Not everyone agrees though. The Future of Food (1hr 29 mins) has the nerve to criticize Monsanto for simply protecting its own rightfully acquired genetic property from thieving farmers. And why do they steel it? Because it’s good for you and it’s going to save the world. (warning: glossy corporate brochure in pdf format).

Are we not men?

zonkout — Tue, 07 Mar 2006 14:19:01 -0800

A Kurdish family in Turkey can only walk on all fours. Some claim that their genetic defects have led to a sort of "backward evolution." An upcoming BBC documentary (pdf) will share their story.

Cock-a-doodle-doo. What, what?

naomi — Sun, 12 Dec 2004 17:38:21 -0800

20,000 genes and splices: the Colonel's Secret Recipe revealed! Even the fanciest chickens won't be able to ignore their genetic cousins now.

Profile my DNA, babe.

moonbird — Sat, 15 Nov 2003 08:10:21 -0800

DNA profiling may be a complex issue, but whatever your take, go ahead and try your hand at genetic sleuthing with this spiffy flash interactive.

Who's You Daddy? Who's Your OTHER Daddy?

jscalzi — Fri, 02 May 2003 10:03:28 -0800

"Jody Has Two Daddies" -- The literal remix. Scientists are making egg cells now, raising the (eventual) possibility of one guy providing the genetic material to raise a crop of eggs, while the other guy provides the crop of sperm (no extra work necessary). Just add one surrogate mother and there you have it: Yet another fundamentalist nightmare, in cute infant "Adam and Steve" form.

Cloned Cat

elpapacito — Tue, 21 Jan 2003 17:12:10 -0800

Cloned Cat Doesn't look and behave like the original cat.Public perception of cloning is clone=original, but we have the proof it isn't always true. Isn't that the proof complex systems doesn't always work like we want, so it'd better to slow down the marketing of genetic engineered food ?

johnnyboy — Thu, 12 Sep 2002 06:01:18 -0800

Is RNAi the future therapeutic approach for tackling everything from AIDS to cancer. Already it is being touted as a molecular biological panacea. A lot of research has been carried out in vitro , just those crucial human trials to go.

mkultra — Fri, 12 Jul 2002 06:50:09 -0800

What the law show say about cloning. Francis Fukuyama and Robert Wright, who have written about technology and "societal evolution", discuss the pros and cons of genetic engineering. This is not a discussion about the finer points of technology, but rather the philosophical implications of moving forward.

martk — Fri, 25 Jan 2002 07:35:16 -0800

Why Genetic Engineering Is So Dangerous Environmentalist/biologist Barry Commoner's essay in the February issue of Harper's magazine warns about the unknown dangers of genetic engineering. "...billions of transgenic plants are now being grown with only the most rudimentary knowledge about the resulting changes in their composition. Without detailed, ongoing analyses of the transgenic crops, there is no way of knowing what hazardous consequences may arise. But, given the failure of the Central Dogma, there is no assurance that they will not. The genetically engineered crops now being grown represent a huge uncontrolled experiment; its outcome is inherently unpredictable. Our project is designed to help develop effective public understanding of the dangerous implications of this critical predicament." He asserts that the "Central Dogma", the basis for the Human Genome Project, was known to be flawed prior to the inception of the $3 billion program. Should we be amused/impressed or very worried when we read about pig/spinach crosses and the like? Related article here.

mdn — Tue, 15 Jan 2002 19:18:54 -0800

Genetic engineering leaves mice impervious to pain. By removing a protein called "DREAM", scientists were able to create rodents that didn't mind extreme heat, pressure and inflammation. This could provide hope for those suffering, or a strange removal from the experience of living, and classic human traits like bravery, strength, volition, and empathy, depending on your view.

elpapacito — Fri, 09 Nov 2001 17:48:52 -0800

Nicote-free cigarette from genetically modified tobacco Apparently a company has developed it and they're running taste-tests too, in stores soon. Looks fine for wannabe smoke quitters. You found another way to get rid of cigs ?

briank — Wed, 22 Aug 2001 06:01:39 -0800

Finally, some genetic modification I can sink my teeth into! Wired reports this morning that an Australian researcher has identified the genetic characteristics for "tenderness" and "toughness" in cow muscle tissue. Aussie cattle ranchers are already gearing up to produce animals that result in more tender, juicier beef. I'm drooling already.