New GM technique injects mosquitoes with a gene that results in mostly male offspring, eventually leading to a population crash.
Previous efforts to tackle the disease, that kills more than 1 million people each year – most of whom are African children – have included bed nets to protect people and insecticides to kill the mosquito species most responsible for the transmission of malaria (Anopheles gambiae
). The new technique by a team at Imperial College London involves injecting mosquitoes with a gene that causes the vast majority of their offspring to be male, leading to an eventual dramatic decline in population within six generations as females disappear. “You have a short-term benefit because males don’t bite humans [and transmit malaria],” Andrea Crisanti, one of the authors of the new research, which was published in the journal Nature Communications on Tuesday
, told the Guardian. “But in the long term you will eventually eradicate or substantially reduce mosquitoes. This could make a substantial contribution to eradicating malaria, combined with other tools such as insecticides.”
These new mosquitoes are now set to be used in Brazil, having been approved for use by the Brazilian government with a factory for their production now opened. [more inside]
posted by Blasdelb
on Aug 14, 2014 -
The large got larger. The small got smaller. The weird got weirder. When you look at sporting achievements over the last decades, it seems like humans have gotten faster, better and stronger in nearly every way. Yet as David Epstein points out in this delightfully counter-intuitive talk, we might want to lay off the self-congratulation. Many factors are at play in shattering athletic records, and the development of our natural talents is just one of them.
TED talk, 14:53
posted by srboisvert
on May 1, 2014 -
Monsanto Is Going Organic in a Quest for the Perfect Veggie
- "The lettuce, peppers, and broccoli—plus a melon and an onion, with a watermelon soon to follow—aren't genetically modified at all. Monsanto created all these veggies using good old-fashioned crossbreeding, the same technology that farmers have been using to optimize crops
for millennia. That doesn't mean they are low tech, exactly. Stark's division is drawing on Monsanto's accumulated scientific know-how to create vegetables that have all the advantages of genetically modified organisms without any of the Frankenfoods ick factor." [more inside]
posted by kliuless
on Mar 8, 2014 -
Spider webs are incredibly strong and flexible. It’s no surprise, then, that spider silk proteins may someday form durable artificial ligaments for people who have injured their knees or shoulders. Six different kinds of silk are produced by orb-web weaving spiders. These silk fibers have very different mechanical properties that are so effective they have changed very little over millions of years. How to synthetically develop these silks is one focus of Lewis’ research. The secret to producing large quantities of spider silk is to use “factories” designed to manufacture spider silk proteins that are easily scale-able and efficient. Lewis uses transgenic goats, E.coli bacteria, transgenic alfalfa and transgenic silk worms to produce the spider silk proteins used to create spider silk. Spider silk is 100 times stronger than natural ligaments and 10 times stronger than natural tendons; it is stronger than Kevlar and more elastic than nylon.
A 6min brief on the work being done in Laramie, WY whereby spider silk is being spun from goat milk. SPIDERGOATS [more inside]
posted by Blasdelb
on Nov 24, 2013 -
"During the most recent ice age, milk was essentially a toxin to adults because — unlike children — they could not produce the lactase enzyme required to break down lactose, the main sugar in milk. But as farming started to replace hunting and gathering in the Middle East around 11,000 years ago, cattle herders learned how to reduce lactose in dairy products to tolerable levels by fermenting milk to make cheese or yogurt. Several thousand years later, a genetic mutation spread through Europe that gave people the ability to produce lactase — and drink milk — throughout their lives. That adaptation opened up a rich new source of nutrition that could have sustained communities when harvests failed." - The Milk Revolution - how a single mutation expanded (some) of humanity's diet. (Nature.com)
posted by The Whelk
on Aug 2, 2013 -
Selfish traits not favoured by evolution, study shows
"Evolution does not favour selfish people, according to new research.
This challenges a previous theory which suggested it was preferable to put yourself first.
Instead, it pays to be co-operative, shown in a model of "the prisoner's dilemma", a scenario of game theory - the study of strategic decision-making.
Published in Nature Communications, the team says their work shows that exhibiting only selfish traits would have made us become extinct. "
posted by marienbad
on Aug 2, 2013 -
The disease that sours oranges and leaves them half green, already ravaging citrus crops across the world, had reached the state’s storied groves. To slow the spread of the bacterium that causes the scourge, they chopped down hundreds of thousands of infected trees and sprayed an expanding array of pesticides on the winged insect that carries it. But the contagion could not be contained.
With a precipitous decline in Florida’s harvest predicted within the decade, the only chance left to save it, Mr. Kress believed, was one that his industry and others had long avoided for fear of consumer rejection.
They would have to alter the orange’s DNA — with a gene from a different species
posted by yeoz
on Jul 28, 2013 -
They came from test tubes. They came pale as ghosts with eyes as blue-white as glacier ice. They came first out of Korea. N-Words
- a science fiction short story by Ted Kosmatka
. Audio version
posted by Artw
on Jul 9, 2013 -
Some of My Best Friends Are Germs
It is a striking idea that one of the keys to good health may turn out to involve managing our internal fermentation. Having recently learned to manage several external fermentations — of bread and kimchi and beer — I know a little about the vagaries of that process. You depend on the microbes, and you do your best to align their interests with yours, mainly by feeding them the kinds of things they like to eat — good “substrate.” But absolute control of the process is too much to hope for. It’s a lot more like gardening than governing.
The successful gardener has always known you don’t need to master the science of the soil, which is yet another hotbed of microbial fermentation, in order to nourish and nurture it. You just need to know what it likes to eat — basically, organic matter — and how, in a general way, to align your interests with the interests of the microbes and the plants. The gardener also discovers that, when pathogens or pests appear, chemical interventions “work,” that is, solve the immediate problem, but at a cost to the long-term health of the soil and the whole garden. The drive for absolute control leads to unanticipated forms of disorder. [more inside]
posted by ninjew
on Jun 1, 2013 -
Private Ceremonies. "Most women don’t talk about their abortions and miscarriages. Virtually none go through the experience with a loved one at their side. The greatest gift an abortion counselor can give is to bear witness, to be with a woman as she goes through this private journey, to witness her strength and weakness, her grief, her relief, her pain."
A first person essay from a former abortion counselor.
posted by zarq
on May 21, 2013 -
Is Psychometric g a Myth?
- "As an online discussion about IQ or general intelligence grows longer, the probability of someone linking to statistician Cosma Shalizi's essay g, a Statistical Myth
approaches 1. Usually the link is accompanied by an assertion to the effect that Shalizi offers a definitive refutation of the concept of general mental ability, or psychometric g
." [more inside]
posted by kliuless
on Apr 11, 2013 -
Extinction got you down? Try de-extinction! Our species has played a role in the extinction of ... many other species. But now some scientists are proposing a radical turn of the tables: Bringing lost species back from the dead. How to Resurrect Lost Species
. [more inside]
posted by heyho
on Mar 16, 2013 -
November 24, 2012: analysis of extensive DNA sequencing of 'a novel hominin hybrid species, commonly called “Bigfoot” or “Sasquatch” ... suggests that the legendary Sasquatch is a human relative that arose approximately 15,000 years ago as a hybrid cross of modern Homo sapiens with an unknown primate species.
' The press release claimed that the research was "currently under peer-review," except that no scientific journal would publish the research, until now: DeNovo
, an open access scientific journal. But DeNovo isn't really open access, as it costs $30 to view the article, the paper itself is brand new, the domain was recently purchased
, and the website features generic stock photos. Ars Technica digs deeper
, summarizing some of the "open access" article, and providing a link to a particularly insightful clip on YouTube
, with an odd water mark. [more inside]
posted by filthy light thief
on Feb 18, 2013 -
Hacking the President’s DNA.
"The U.S. government is surreptitiously collecting the DNA of world leaders, and is reportedly protecting that of Barack Obama. Decoded, these genetic blueprints could provide compromising information. In the not-too-distant future, they may provide something more as well—the basis for the creation of personalized bioweapons that could take down a president and leave no trace."
posted by homunculus
on Oct 26, 2012 -
When looking for inspiration, most songwriters to go well-used emotional wells – triumph or loss, love or heartbreak. But Peter Larsen, a biologist at Argonne National Laboratory, looked to the microbes of the English Channel. He used seven years’ worth of genetic and environmental data, converting geochemical and microbial abundance measurements into notes, beats, and chords.
posted by Egg Shen
on Oct 8, 2012 -
In 2001, we learned the sequence of our genome; now, we have amassed a vast amount of knowledge about what those sequences actually do
. Yesterday, the data from the ENCODE
project went live. [more inside]
posted by Westringia F.
on Sep 6, 2012 -
Ötzi the Iceman
died around 3,300 B.C., yet his body was preserved frozen in the Alps until 1991. DNA sequencing
of Neandertals (who died out about 35,000 years ago) suggests modern humans with ancestry outside of Africa carry a few percent of Neandertal genes due to interbreeding. Now (in a blog post knocking down a re-interpretation of the Neandertal DNA evidence) paleontologist John Hawks previews an upcoming publication of his examining Ötzi's DNA:
If we took as a baseline that Europeans have an average of 3.5 percent Neandertal, Ötzi would have around 5.5 percent (again, the actual percentage would be highly model-dependent). He has substantially greater sharing with Neandertals than any other recent person we have ever examined.
, Previously (Neandertals)
posted by Schmucko
on Aug 18, 2012 -
A relatively small group of people from Appalachian, the dark-skinned Melungeons (previously)
have been a source for speculation and conjecture for many years. Exactly who where their ancestors? Portuguese? Turks? Roma? Cherokee? A recent DNA study
(108 page pdf) posted in the Journal of Genetic Genealogy (site link
) says otherwise
posted by edgeways
on May 24, 2012 -