The Fat Trap (NYT pop review): Overweight individuals in Western nations (and, increasingly, beyond) face interpersonal and institutional stigma for their bodies*. Oftentimes, these stigmas are predicated on the belief that being overweight is a moral failure, that being overweight is usually a result of laziness, decadence, and/or characterlogical poor impulse control. However, an emerging consensus among obesity researchers points toward strong, common physiological and individual genetic factors as causative for heightened BMIs in the modern world and the general failure of dieting to produce BMI outcomes. A recent study in the New England Journal of Medicine (paywalled) adds to this body of evidence, suggesting that chemical messengers held to contribute to altered "efficient" metabolism and increased hunger in the wake of low-calorie dieting are (on average) significantly elevated up to a full year (if not longer) following a substantial drop in weight from dieting. [more inside]
posted by Keter on Dec 28, 2011 - 173 comments

The New Biology - Eric Schadt's quest to upend molecular biology and open source it. (via)
posted by kliuless on Apr 9, 2011 - 35 comments

In 1926, Nikolai Vavilov founded the world's first modern seedbank, and amassed a collection which today contains over 90% unique varieties of plant, contained in no other collection in existence. For his opposition to Lysenkoism he died in prison, and several of his colleagues famously starved to death instead of eating their specimens during the Siege of Leningrad. Now the Pavlovsk seedbank facility has been seized by the Federal Agency for Public Estate Management, and pending a court ruling will be demolished - contents and all - to build a housing development. The collection cannot be moved in time because it is a working seedbank of living plants.
posted by mek on Aug 9, 2010 - 40 comments

grumblebee's post about cell size and scale the other day was quite fascinating. Pulling back to the home for that site, the Genetic Science Learning Center at the University of Utah delivers educational materials on genetics, bio-science and health topics ranging from stem cells to gene therapy, and from epigenetics to heredity. Explore the neurobiology of normal and addicted brains and the genetic contribution to this chronic disease.
posted by netbros on Oct 31, 2009 - 4 comments

Scientists Repurpose Adult Cells - "Scientists have transformed one type of fully developed adult cell directly into another inside a living animal, a startling advance that could lead to cures for a variety of illnesses and sidestep the political and ethical quagmires associated with embryonic stem cell research." [nature abstract, nature writeup, audio announcement]
posted by kliuless on Aug 27, 2008 - 21 comments

Bisphenol A: this extremely common chemical leaches out of food packaging and plastics, and was long considered safe. But a number of recent studies link it to developmental problems and cancer in lab animals in doses far lower than the current regulatory limit. Canada and the United States both review the scientific data available in the coming months, but critics already worry the process will be corrupted by industry. Industry, of course, insists that BPA is safe.
posted by mek on Apr 7, 2007 - 32 comments

In terms of our genes, we humans are all the same -- except for the ways in which we're different. Pharmacogenomics has for years been touted as the ultimate benefit of the genomics revolution. But to many, this revolution has a troubling side.
posted by semmi on Oct 13, 2004 - 6 comments

Godsend Institute offers up this explanation of their cloning procedures. Since Dolly, several scientists have cloned other animals, including cows and mice. Now, at Godsend, we have pioneered a technique that allows a cell nucleus from a recently deceased child to be implanted within a human egg, allowing a mother to carry that child to term again.
posted by sciatica on Apr 15, 2004 - 33 comments

Making the Mind. "The general outlines of how genes build the brain are finally becoming clear, and we are also starting to see how, in forming the brain, genes make room for the environment’s essential role. While vast amounts of work remain to be done, it is becoming equally clear that understanding the coordination of nature and nurture will require letting go of some long-held beliefs."
posted by homunculus on Jan 17, 2004 - 16 comments

In lieu of today's posts on GM foods and meat, Trans Ova Genetics is pharming cows in hopes of creating one capable of adminstering human antibodies.
posted by hobbes on Aug 25, 2003 - 5 comments

CCR5 This gene encodes for a protein on T cells that allows HIV to enter and replicate. It's also another reason why AIDS has less of an effect on European populations - 10-15% of Northern Europeans carry a defect that doesn't allow the attachment, so 1% or so is homozygous for the 'faulty' gene and appears to be completely resistant to HIV/AIDS.
posted by phoenix enflamed on Dec 1, 2001 - 1 comment

A success for gene therapy to help hemophiliacs is announced. This is a first, but only time will tell if the treatment has a lasting effect and can be repeated. So far it's worked for only four of the six patients in the trial. The NY Times explains the research.
posted by caraig on Jun 7, 2001 - 5 comments