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The world’s worst disease

While many ailments are considered terrifying, Lesch-Nyhan is the stuff of nightmares. An extremely rare genetic neurological disorder with no cure, it often compels its victims to self-mutilate, even when they understand that doing so causes them harm. Richard Preston used Lesch-Nyhan as a plot device in his best-selling thriller The Cobra Event, and went on to write a fascinating article about the disease, its sufferers, and its implications for human behavior in the New Yorker. [PDF]. [more inside]
posted by Bora Horza Gobuchul on Jun 5, 2008 - 35 comments

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