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3 posts tagged with Pathogenesis. (View popular tags)
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Blasdelb (2)

HPV: Sex, cancer and a virus

"On a sunny day in 1998, Maura Gillison was walking across the campus of Johns Hopkins University in Baltimore, Maryland, thinking about a virus. The young oncologist bumped into the director of the university's cancer centre, who asked politely about her work. Gillison described her discovery of early evidence that human papillomavirus (HPV) — a ubiquitous pathogen that infects nearly every human at some point in their lives — could be causing tens of thousands of cases of throat cancer each year in the United States. The senior doctor stared down at Gillison, not saying a word. “That was the first clue that what I was doing was interesting to others and had potential significance,” recalls Gillison."
Human papillomavirus is causing a new form of head and neck cancer— leaving researchers scrambling to understand risk factors, tests and treatments.
[more inside]
posted by Blasdelb on Nov 22, 2013 - 37 comments

Markovian Parallax Denigrate

But back in 1996, users of the proto-Web community Usenet got spammed with messages that reached an almost transcendent level of bizarre—a weirdness so precise it implied the influence of a very human intelligence. “Markovian Parallax Denigrate,” read the title of each post, followed by a mountain of seemingly meaningless word spew:
Unraveling the Internet’s oldest and weirdest mystery
posted by the man of twists and turns on Nov 20, 2012 - 68 comments

Virulence-transmission trade-offs and population divergence in virulence

"Why do parasites harm their hosts? Conventional wisdom holds that because parasites depend on their hosts for survival and transmission, they should evolve to become benign, yet many parasites cause harm. Theory predicts that parasites could evolve virulence (i.e., parasite-induced reductions in host fitness) by balancing the transmission benefits of parasite replication with the costs of host death. This idea has led researchers to predict how human interventions—such as vaccines—may alter virulence evolution, yet empirical support is critically lacking." Two papers demonstrate empirical evidence for related models predicting the origin of virulence: [more inside]
posted by Blasdelb on Oct 21, 2012 - 23 comments

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