Ben Goldacre, The Guardian
: "Today we found out that Tamiflu doesn't work so well after all. Roche, the drug company behind it, withheld vital information on its clinical trials for half a decade, but the Cochrane Collaboration, a global not-for-profit organisation of 14,000 academics, finally obtained all the information. Putting the evidence together, it has found that Tamiflu has little or no impact on complications of flu infection, such as pneumonia." [more inside]
posted by Wordshore
on Apr 10, 2014 -
More than half the population of small, rural Madras, Oregon (population: ~6059) and its surrounding community is served by one clinic: Madras Medical
. At the beginning of 2006, the clinic's doctors and nurses decided to ban pharmaceutical reps from visiting their practice. No more free lunches. No more free drug samples. No more gifts. And yet.... "It's made us better doctors." (Via) [more inside]
posted by zarq
on Aug 27, 2013 -
has been talked about here before
. This year, following on from his book Bad Pharma
- where he described a culture of badly-done medical trials on unsuitable subjects (sometimes with horrific but, tragically, potentially preventable outcomes
), where swathes of results that don't reflect well on the drug in question go unpublished and even, in some cases, hidden - he has co-founded the project AllTrials
, which campaigns for all
medical trials to be recorded and reported. [more inside]
posted by greenish
on Feb 4, 2013 -
Antipsychotics: "The magnitude of publication bias found for antipsychotics was less than that found previously for antidepressants, possibly because antipsychotics demonstrate superiority to placebo more consistently."
: "We found a bias toward the publication of positive results. Not only were positive results more likely to be published, but studies that were not positive, in our opinion, were often published in a way that conveyed a positive outcome. [...] Using both approaches, we found that the efficacy of this drug class is less than would be gleaned from an examination of the published literature alone. According to the published literature, the results of nearly all of the trials of antidepressants were positive. In contrast, FDA analysis of the trial data showed that roughly half of the trials had positive results."
Previously [more inside]
posted by OmieWise
on Apr 3, 2012 -
Small firms develop better peptide drug candidates to expand this pharmaceutical class and attract big pharma partners
posted by Blasdelb
on Jun 2, 2011 -
A major advance in genetically modified foods.
Developed with government funding, and intended eventually to be given away to farmers, there has been a major success in the use of salt water to irrigate crops. They've developed a tomato which grows fine in salt water or on salty soil. Thousands of lives will be saved in parts of the world where fresh water for irrigation is scarce, including up to one third of the arable land in India where salt has been accumulating. Interestingly, these tomatoes are so good at what they do that they remove salt from the soil, improving it. The genetic modification which was done to these tomatoes should be possible with many other crops, including especially rice (on which major effort in Egypt is underway now).
posted by Steven Den Beste
on Jul 30, 2001 -
Monsanto wins case against Canadian farmer
. Percy Schmeiser
, who has attained folk-hero status, was held liable for growing genetically modified canola without paying the royalty. The decision in a federal court in Saskatoon, Saskatchewan, was a significant setback for farmers who fear they will be held liable if pollen from neighboring farms blows onto their fields, transmitting patented genes to their crops without their knowledge or consent.
posted by gimli
on Mar 30, 2001 -