In 2004, Minnesota student Dan Markingson committed suicide while participating in a clinical drug trial
for various mood disorders. Trial sponsors the University of Minnesota and AstraZeneca were cleared of blame by the FDA in 2005. Last week, a group of faculty members at the university wrote an open letter
to the university's Board of Regents requesting further investigation due to "troubling questions" that remain unanswered and a concern over "conflicts of interest" in the Academic Health Center.
posted by modernnomad
on Dec 6, 2010 -
Ecstasy's long-term effects revealed.
"Enough time has finally elapsed to start asking if ecstasy damages health in the long term. According to the biggest review ever undertaken
, it causes slight memory difficulties and mild depression, but these rarely translate into problems in the real world. While smaller studies show that some individuals have bigger problems, including weakened immunity and larger memory deficits, so far, for most people, ecstasy seems to be nowhere near as harmful over time as you may have been led to believe." [Via]
posted by homunculus
on Feb 12, 2009 -
Predicting who'll benefit from anti-depressants
From the study's abstract: "There are well-replicated, independent lines of evidence supporting a role for corticotropin-releasing hormone (CRH) in the pathophysiology of depression." The NY Times has a bit more readable explanation
(reg-free link) of a recent investigation of into whether there is a genetic explanation for why some people get more from their drugs than others.
posted by billsaysthis
on Dec 18, 2004 -
In terms of our genes
, we humans are all the same -- except
for the ways in which we're different. Pharmacogenomics has for years been touted as the ultimate benefit of the genomics revolution. But to many, this revolution has a troubling side.
posted by semmi
on Oct 13, 2004 -
Dr. Donald Francis
He was portrayed by Mathew Modine in the classic HBO film And the Band Played On
, which told the story of how he discovered the AIDS virus 20 years ago. Earlier in his career he was a key member of the team that wiped out Smallpox (although he couldn't argue a few governments from keeping samples on ice just in case
) and the team that figured out how to contain outbreaks of the flesh eating Ebola virus--that was essentially him, though not his personality, that Dustin Hoffman played in Outbreak
. Now he's the president and chief scientist of Vaxgen, a company that expects to receive positive result from its Phase III human clinical trials of AIDSVAX
shortly after New Year's. If the results are as expected, AIDSVAX will be the first AIDS vaccine to go into production.
Like any other major issue in our age of delusions and self-deceptions, there are doubters and paranoids and conspiracy theorists too. Here is a neat little example of all three bundled up in one, from a publication titled The Aids Mirage
: Donald Francis invents a viral epidemic
. All the stop energy embodied by such efforts are really sad.
posted by billsaysthis
on Dec 1, 2002 -
Poor Eli Lilly
is going to lose it's Prozac patent protection soon, though not quite yet. via Follow Me Here
posted by dcodea
on Nov 16, 2000 -