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7 posts tagged with Psychopharmacology. (View popular tags)
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homunculus (2)

Drugs in context

Dr. Carl Hart, psychopharmacologist at Columbia, bust pernicious drug myths and talks provocatively about race and the "War on Drugs."
posted by klangklangston on Jul 6, 2013 - 114 comments

Operation Delirium

Operation Delirium. "The military’s secret Cold War experiment to fight enemies with clouds of psychochemicals. Decades after a risky Cold War experiment, a scientist lives with secrets." [Via]
posted by homunculus on Dec 10, 2012 - 44 comments

Dirty Pictures

Dirty Pictures [1h30m] is a documentary (trailer [1m30s]) about Alexander Shulgin, his life, his family, the drugs he has developed, the people he has affected, the boundaries of experience he has explored, the effects he has had on society, and the understanding of the mind and the psychedelic experience which have resulted from his experiments and chemical creations.
posted by hippybear on Apr 4, 2012 - 23 comments

Falling STAR*D?

Falling STAR*D?: It is common practice for psychiatrists to switch depressive patients between different antidepressants if their current drug does not evince a symptomatic response. Despite clinical wisdom supporting this, little empirical, controlled evidence exists to direct “switching” protocols (e.g. if a patient with Z characteristics is on drug X, is it usually better to switch to drug A, B, or C? Will switching help at all?) in the psychopharmacological treatment of depression. The NIMH-funded STAR*D (Sequenced Alternatives to Relieve Depression) study aimed to address these questions of treatment direction in a very large (n>4000), “real-world” sample using a multi-phase treatment plan with different drugs (and cognitive therapy) at every step to maximize chances of eventual remission. Overall, the NIMH reported that about 67% of patients eventually achieved remission, with few differences in effectiveness between different types of treatment at each step. However, researchers and commentators have raised concerns regarding inconsistent reporting of outcomes, after-the-fact changes in study design and analysis, and other issues that may have inflated, partially invalidated, or misrepresented widely reported treatment outcomes. These inequities may also have implications for the secondary moderator analyses (i.e. does trait A predict switching to X or Y is better?) that were a major reason for the study. [more inside]
posted by Keter on Jan 14, 2012 - 12 comments

The Model of a Psychopharmacologist

I Am the Very Model of a Psychopharmacologist. [Via Omni Brain.]
posted by homunculus on Nov 19, 2007 - 33 comments

The Emperor's New Drugs

It is America's most profitable industry, number one in return on revenues, return on assets, and return on equity. From barbiturates, to benzodiazepines, to everyone's favorite delysid, we come to the new age: SSRI's. There are thousands of studies showing that they work. And very few that question their efficacy. (very informative meta-analysis, a follow-up [pdf]). A quantitative explanation.
posted by dminor on Jul 13, 2006 - 72 comments

Psychoactive Drugs for the Future

Psychoactive Drugs for the Future Could brain-boosting drugs become as common as coffee?
UK government group Foresight have just released their 'Brain Science, Addiction and Drugs Project' in which the aim was to evaluate:
"How can we manage the use of psychoactive substances in the future to best advantage for the individual, the community and society?"
The report can be viewed in its entirety from here. Direct link to the Executive Summary (.pdf) via
posted by peacay on Jul 15, 2005 - 31 comments

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