"Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets." After an extensive, months-long debate, one of two controversial papers showing ways the H5N1 "avian" influenza virus could potentially become transmissible in mammals with only 3 or 4 mutations was published in Nature today. The journal included an editorial on the merits and drawbacks of "publishing risky research" with regard to biosafety. The debate included an unprecedented recommendation by The US National Science Advisory Board for Biosecurity (NSABB) to block publication -- a decision they later reversed. (Via: 1, 2) Nature's special report has additional articles, including interviews with the teams behind both papers.
posted by zarq on May 3, 2012 - 37 comments

How to read a paper is a series by Trisha Greenhalgh in BMJ, the British Medical Journal, that explains how to critically read and apply the biomedical literature. Deciding what the paper is about. Assessing methodological quality. Statistics for the non-statistician: parts I and II. Drug trials, diagnostic and screening tests, economic analyses, systematic reviews and meta-analyses (PDF), and qualitative research (PDF).
posted by grouse on Apr 19, 2012 - 14 comments

London Lives 12 London archives – digitised, marked up and tagged – to "create a comprehensive electronic edition of primary sources on criminal justice and the provision of poor relief and medical care in eighteenth-century London". The Lives page is a good place to start browsing. [related]
posted by unliteral on Jun 8, 2010 - 8 comments

A Good Poop is an entertaining blog by an occupational and environmental health student who enjoys finding oddities in medical and scientific research from PubMed. (via Look at This...)
posted by madamjujujive on Aug 20, 2008 - 42 comments

Could Alzheimer's be a form of diabetes?
Well, I'm not looking forward to taking those insulin shots....via Medgadget
posted by lilboo on Nov 30, 2005 - 11 comments

First Documented Case of HIV hybridization in a human being was presented at the International AIDS Society conference in Paris. In this case, genetic tests on a superinfected woman showed that the two strains she was infected with swapped genetic material, creating a new hybrid strain of HIV. The actual effects are not yet clear, but this could pose a serious problem for researchers trying to create a vaccine.
posted by Irontom on Jul 16, 2003 - 8 comments

China hopes to make a great leap forward in Stem Cell Research Does anyone else find this a little troubling? Are all the clones going to look like Jiang Zemin?
posted by AsiaInsider on Mar 6, 2002 - 18 comments

Patient confidentiality vs. cancer research. New rules on patient confidentiality prevent "research that recognises dangerous side effects of treatments and it would prevent research that would recognise avoidable causes of diseases and death. " What is more important: 'medical progress' or 'your medical file'?
posted by nonharmful on May 19, 2001 - 2 comments