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In a recent paper published in Nature Hansen et al. show the efficacy of their unusual vaccine strategy against SIV_MAC239 in rhesus macaques. While the goal is not necessarily to produce a human vaccine against HIV using this exact strategy, this paper is now reigniting the debate over the progression of HIV infections and the mechanism(s) by which the virus skirts the human immune system.
posted by Blasdelb on May 13, 2011 - 4 comments

The HIV ancestor virus, SIV, has been around much longer than previously thought. The NY Times notes: "And that assumption in turn complicates a question that has bedeviled AIDS scientists for years: What happened in Africa in the early 20th century that let a mild monkey disease move into humans, mutate to become highly transmissible and then explode into one of history’s great killers, one that has claimed 25 million lives so far?" [more inside]
posted by questionsandanchors on Sep 16, 2010 - 61 comments

At a time when fed-up American citizens are petitioning Congress to end the imprudent financial practices that caused the housing bubble sub-prime mortgage crisis liquidity crisis impending recession -- including the banning of SIV's and refusing any bailouts for Wall Street, banks, or mortgage companies -- the United States Treasury Department has just announced the creation of a giant-mega-ultra SIV called "M-LEC" made up of assets from several of the largest American banks. Already unofficially nicknamed "Sivie Mae" (or worse, "the Frankenstein Fund"), it would be an off-balance-sheet way for these banks to pool and price the ABCP's that they've lately been having trouble pricing and thus selling -- i.e. the liquidity crisis. [more inside]
posted by Asparagirl on Oct 16, 2007 - 82 comments

AIDS really did come from chimps in the 1950s --..."We're 25 years into this pandemic," Hahn said. "We don't have a cure. We don't have a vaccine. But we know where it came from. At least we can make a check mark on one of those." ... ...Identifying the source of the HIV pandemic is more than filling in a missing link in the disease's progression. ...
posted by amberglow on May 25, 2006 - 25 comments

The Hunt for the Origin of AIDS "The notion that AIDS arose from a polio vaccine made with contaminated chimpanzee cells is far from the only theory about how the epidemic started, and it is hotly disputed. The quest for the source of the epidemic is intensifying, as researchers scour the jungle for clues and try to "walk back" the disease genetically with the help of the world's most powerful computers."
posted by the fire you left me on Dec 1, 2002 - 2 comments