Inside the insectary - "These gene drives, they're able to copy themselves. So instead of half of the offspring inheriting the gene drive, almost all of them do. So what happens is that it spreads and it spreads and it spreads. And this is the fantastic thing. Because it allows that gene to be selfish in a population. And in a very short amount of time you can actually transform an entire wild population into a modified population. It's powerful." (previously: 1,2,3)
The Inevitable Evolution of Bad Science "Now, imagine you’re a researcher who wants to game this system. Here’s what you do. Run many small and statistically weak studies. Tweak your methods on the fly to ensure positive results. If you get negative results, sweep them under the rug. Never try to check old results; only pursue new and exciting ones. These are not just flights of fancy. We know that such practices abound."
The Evolution of Bacteria on a “MEGA-Plate” Petri Dish - a cinematic approach to visualizing drug resistance
From deities to data - "For thousands of years humans believed that authority came from the gods. Then, during the modern era, humanism gradually shifted authority from deities to people... Now, a fresh shift is taking place. Just as divine authority was legitimised by religious mythologies, and human authority was legitimised by humanist ideologies, so high-tech gurus and Silicon Valley prophets are creating a new universal narrative that legitimises the authority of algorithms and Big Data." [more inside]
Meet Graham, an interactive sculpture developed by a trauma surgeon, a crash investigation expert and a Melbourne artist to show what humans might look like, if they had evolved features to withstand car crashes (via)
In his follow-up to Sapiens, Yuval Noah Harari envisions what a 'useless class' of humans might look like as AI advances and spreads - "I'm aware that these kinds of forecasts have been around for at least 200 years, from the beginning of the Industrial Revolution, and they never came true so far. It's basically the boy who cried wolf, but in the original story of the boy who cried wolf, in the end, the wolf actually comes, and I think that is true this time." [more inside]
How Technology Is Changing Our Hands by Darian Leader [The Guardian] Doctors predict that our increasing use of computers and mobile phones will permanently alter our hands. What will this mean for the way we touch, feel and communicate? [more inside]
Siddhartha Mukherjee's latest New Yorker article "Same but different: How epigenetics can blur the line between nature and nurture" has attracted searing criticism from heavyweight researchers in the field. Mukherjee responds but doesn't retract...
An evolutionary burst 540 million years ago filled the seas with an astonishing diversity of animals. The trigger behind that revolution is finally coming into focus , according to the journal Nature. [more inside]
Creatures avoiding planks - "After around a thousand generations of training, the agents became half decent at avoiding planks. Please see the final result in this demo." [more inside]
Sure, we may be a little weird compared to our close relatives for not having a baculum (penis bone), and maybe that's the sort of thing you want to explain for whatever reason, but does human penis size and shape need a uniquely human story? Assuming it's correlated to the vagina like it probably is in many other species, then no it doesn't... unless the size and shape of the human vagina has an exceptional story. Does it? We wouldn't know. [more inside]
Humans 2.0 - "With CRISPR, scientists can change, delete, and replace genes in any animal, including us. Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis. One group has replaced a mutation that causes cataracts; another has destroyed receptors that H.I.V. uses to infiltrate our immune system." [more inside]
Sapiens: A Brief History of Humankind by Yuval Noah Harari - "The book delivers on its madly ambitious subtitle by in fact managing to cover key moments in the developmental history of humankind from the emergence of Homo Sapiens to today's developments in genetic engineering." Also btw, check out Harari on the myths we need to survive, re: fact/value distinctions and their interrelationships.
From the Neurologica blog: "Creationists are engaged in science denial—denying evolutionary science. The purpose of denial is doubt and confusion, so they don’t have to create and defend a coherent explanation of the origins of life on Earth. They don’t have to provide an explanation for all the available evidence. All they have to do is muddy the waters as much as possible." [more inside]
"Humans as Superorganisms: How Microbes, Viruses, Imprinted Genes and Other Selfish Entities Shape Our Behavior" by Peter Kramer and Paola Bressan discusses the idea that an individual homo sapiens is only one component of the human superorganism we call a person, focusing on the psychological and psychiatric ramifications thereof. (Paola Bressan previously.)
Teleotheism and the Purpose of Life - "Please give this sermon a try. I think it has much in it that will be of interest to a wide range of readers: philosophy, cosmology, evolutionary theory, and science fiction, as well as theology. And nothing in it depends on believing in God at all." Abstract: As an enlightened form of atheism, I turn to teleotheism. Teleotheism is the view that God comes at the end, not at the beginning, where I am defining “God” as “the greatest of all things that can come true.” In this view, the quest to discover what are the greatest things that are possible is of the utmost importance. The best of our religious heritage is just such an effort to discover the greatest things that are possible. (via; previously)
Some Paths to the True Knowledge[*] - "Attention conservation notice: A 5000+ word attempt to provide real ancestors and support for an imaginary ideology I don't actually accept, drawing on fields in which I am in no way an expert. Contains long quotations from even-longer-dead writers, reckless extrapolation from arcane scientific theories, and an unwarranted tone of patiently explaining harsh, basic truths. Altogether, academic in one of the worst senses. Also, spoilers for several of MacLeod's novels, notably but not just The Cassini Division. Written for, and cross-posted to, Crooked Timber's seminar on MacLeod, where I will not be reading the comments."
Scientists say they have reversed a bit of bird evolution in the lab and re-created a dinosaurlike snout in developing chickens.
Biologist/blogger PZ Myers provides a nice introduction to evolutionary theory, and explains how classical Darwinism is distorted by proponents of scientific racism and other pseudoscientific movements.
This is my vision of life. A conversation with evolutionary biologist and author Richard Dawkins. (Video and transcript)
"What could you possibly have in common with a mushroom, or a dinosaur, or even a bacterium? More than you might think. In this Lab, you’ll puzzle out the evolutionary relationships linking together a spectacular array of species. Explore the tree of life and get a front row seat to what some have called the greatest show on Earth. That show is evolution." Evolution Lab is a educational game created by the Life on Earth Project and NOVA Labs
Associate Professor Rana Dajani describes why she teaches evolution to Muslim students in Jordan.
The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
I’m occasionally told my life would be easier if I backed off from my relentless efforts to advance evolution education. Maybe so. But to shy away from emphasizing evolutionary biology is to fail as a biology teacher. I continue to teach biology as I do, because biology makes sense only in the light of evolution.
Troubles in Paradise is a review of the history and arguments of the creationism/intelligent design movement, written by James Downard.
I waited silently for her to explain that the female pelvis is shaped slightly differently from the male’s, with a larger opening for childbearing. That part was the giveaway. The real purpose of the exercise was to make her prove her conjecture with measurements--to translate the theory to practice. I also wanted her to explain why this sexual dimorphism--that is, this sexually determined physical difference--is not nearly so pronounced in nonhuman primates, such as chimpanzees.When teacher Robert S. Root-Bernstein got this answer to his question on how you should distinguish between male and female skeletons, he had to find a way to make her realise her error without disparaging her religion.
She spoke: Males have one fewer pair of ribs than females.
You invest so much in it, don't you? It's what elevates you above the beasts of the field, it's what makes you special. Homo sapiens, you call yourself. Wise Man. Do you even know what it is, this consciousness you cite in your own exaltation? Do you even know what it's for?Dr. Peter Watts is no stranger to MetaFilter. But look past his sardonic nuptials, heartbreaking eulogies, and agonizing run-ins with fascists (and fasciitis) and you'll find one of the most brilliant, compelling, and disquieting science fiction authors at work today. A marine biologist skilled at deep background research, his acclaimed 2006 novel Blindsight [full text] -- a cerebral "first contact" tale led by a diverse crew of bleeding-edge post-humans -- is diamond-hard and deeply horrifying, wringing profound existential dread from such abstruse concepts as the Chinese Room, the Philosophical Zombie, Chernoff faces, and the myriad quirks and blind spots that haunt the human mind. But Blindsight's last, shattering insight is not the end of the story -- along with crew/ship/"Firefall" notes, a blackly funny in-universe lecture on resurrecting sociopathic vampirism (PDF - prev.), and a rigorously-cited (and spoiler-laden) reference section, tomorrow will see the release of
Your body is home to about 100 trillion bacteria and other microbes, collectively known as your microbiome. Naturalists first became aware of our invisible lodgers in the 1600s, but it wasn’t until the past few years that we’ve become really familiar with them. This recent research has given the microbiome a cuddly kind of fame. We’ve come to appreciate how beneficial our microbes are — breaking down our food, fighting off infections and nurturing our immune system. It’s a lovely, invisible garden we should be tending for our own well-being. But in the journal Bioessays, a team of scientists has raised a creepier possibility. Perhaps our menagerie of germs is also influencing our behavior in order to advance its own evolutionary success — giving us cravings for certain foods, for example.[more inside]
Koryos, who previously explained how cats got domesticated using tumblr, now explains why homosexual pair-bonding can be a successful reproductive stratagem. Also, Coot Parenting Tips, Queen Cowbird Of The Brood Parasites , There's No Such Thing As An Alpha Wolf, and Can Animals Have Pets?
With growing fascination for the large land vertebratomorphs that are so startlingly diverse on Tatooine, I secured Imperial funding for an expedition to Tatooine, to survey the exotic megafauna and search for fossils of Tyrannodraconis that might further illuminate their evolution. My ensuing report summarizes my trilogy of investigations and discoveries from this “holiday in the suns." [more inside]
"Peter and Rosemary Grant are members of a very small scientific tribe: people who have seen evolution happen right before their eyes."
Evolutionary biologists at Northumbria University have used science to figure out "attractive human dance moves" that demonstrate optimum genotypic and phenotypic health to prospective mates. "Cutting-edge motion capture technology" was used to record good and bad dancing. (Technoviking was reportedly unpleased.)
Bill Nye is debating the head of the Creation Museum tomorrow. Ken Ham, founder of Northern Kentucky tourist attraction "Answers in Genesis" Creation Museum, has challenged Science Guy Bill Nye to a duel, errr, a debate. Nye, while tolerant of Ham's religious beliefs, draws the line at creationism creeping into science curriculum. More pre-event throwdowns are here. [more inside]
This 419-Million-Year-Old Fish Has the World’s Oldest Known Face What makes it remarkable is everything that’s come after it: It’s the oldest known creature with a face, and may have given rise to virtually all the faces that have followed in the hundreds of millions of years since, including our own.
In March 2012, inspectors from the U.S. Department of Agriculture uncovered a problem in Elgin, Texas. Beef sausage from a small family-run meat processor appeared to have been contaminated with a nasty bacterium called Listeria monocytogenes. The bug can make people sick and, in rare cases, be deadly. The processor had to recall more than a ton of sausage. It’s the kind of story that strikes terror in the hearts of other sausage peddlers, including Mike Satzow, so he uses phages to keep his small company's sausages safe to eat.
Unleashing Genetic Algorithms on the iOS 7 Icon - In the pursuit of something just a bit tighter than Marc Edwards' superellipse approximation, Mike Swanson applies genetic algorithms to the task of making a better button-making script.
In the past few days, the Internet has been filled with commentary on whether the National Science Foundation should have paid for my study on duck genitalia, and 88.7 percent of respondents to a Fox news online poll agreed that studying duck genitalia is wasteful government spending. The commentary supporting and decrying the study continues to grow. As the lead investigator in this research, I would like to weigh in on the controversy and offer some insights into the process of research funding by the NSF.
Come for the passionate defense of basic science, stay for the explosive eversion of a duck penis.[more inside]
With incisor-like claws that can tunnel beneath your skin in seconds, ticks are rapidly establishing themselves as the Swiss Army knife of disease vectors. Carl Zimmer walks into the woods to find out why these tiny beasts appear to be skyrocketing in number – and outsmarting environmental scientists trying to control them with every bite.
Researchers have found that size does matter as it relates to overall proportions of the male body (PNAS link, PDF)
seaQuest: what if we could learn to live on/underneath the oceans (or in orbit)? [previously(er)] [more inside]