X inactivation is a type of gene dosage compensation. In humans, the sex chromosomes X and Y determine the sex of an individual - females have two X chromosomes (XX), males have one X and one Y chromosome (XY). All of the genes on the Y chromosome are required in male development, while the genes on the X chromosome are needed for both male and female development. Because females receive two X chromosomes, they inherit two copies of many of the genes that are needed for normal function. Extra copies of genes or chromosomes can affect normal development. An example is Down's syndrome, which is caused by an extra copy of part or all of chromosome 21. In female mammals, a process called X inactivation has evolved to compensate for the extra X chromosome. In X inactivation, each cell 'switches off' one of its X chromosomes, chosen at random, to ensure the correct number of genes are expressed, and to prevent abnormal development.
Here is a helpful eleven minute description of what it is and why it's important by Etsuko Uno and metafilter's own Drew Berry in a fucking gorgeous Goodsell-esque 3D animation. [more inside]
posted by Blasdelb
on Sep 14, 2013 -
: Even if your Alphabet Conspiracy succeeds and you destroy the books, machines have no minds of their own. They are easily confused by different voices and different accents. It is the brain of man that tells them what to do. [more inside]
posted by filthy light thief
on Aug 20, 2010 -
In 2001, Marc Bertrand
was tasked by the National Film Board of Canada with creating 26 one-minute films about science. The only constraints were that he had to use both archival footage and animation. The result was Science Please!
And because the NFB is awesome, you can watch all 26 of them online: Part 1
| Part 2
| Or, in French [more inside]
posted by 256
on Apr 26, 2010 -
Record player + video camera = Phonographantasmascope
, animator Jim LeFevre's extension of the zoetrope. "It is all live action and works by using the shutter speed of the camera rather than the rather irritating stroboscope methods other 3D Zoetropes use."
posted by nthdegx
on Jun 23, 2008 -
Visualizations of recent and historical tsunami episodes, collected by John McDaris at Carleton College. Includes large but visually effective animations, such as this NOAA visualization
of the global propagation of the 26/12/04 tsunami (24MB Quicktime).
posted by carter
on Feb 1, 2005 -