Darker Projects has a bunch of original audio dramas in the sci-fi, horror, and suspense vein. Think of it as your local community audio-only theatre, or not-actually-old-timey old-time radio.
posted on Jun 1, 2008 - View this thread

Symmetry. Shakespeare. Islamic medicine. Creative writing challenges. Four podcast series from University of Warwick.
posted on Nov 18, 2007 - View this thread

Astronomy Media Player - a generous collection of astronomy podcasts all gathered in one spot.
posted on Oct 8, 2007 - View this thread

Lit2Go - tons of stories, tales and poems suitable for younger readers: HTML, PDF, and MP3s. From Baa, Baa, Black Sheep to Jane Eyre, Frankenstein, and Flatland.
posted on Aug 9, 2007 - View this thread

More fodder for your mp3 player - audio books of Hesse, Kafka, Nietzsche, Plato, Tennyson, and quite a bit more from ThoughtAudio.
posted on Apr 12, 2007 - View this thread

Huck Finn, Heart of Darkness, A Tale of Two Cities, and others - free audio books. Text and audio on the web, or downloadable mp3s with embedded text.
posted on Mar 4, 2007 - View this thread