Nanowire Mesh Monitors Mouse Brains - "Injectable 'neural lace'* brain-computer interface works in mice for months at a time." (via) [more inside]
Let these chipper YouTube science vids fill you with existential terror. Popular YouTube education channels CGP Grey and Kurzgesagt teamed up to produce a pair of videos designed to cause you to question everything about your existence.
"In a stunning discovery that overturns decades of textbook teaching, researchers at the University of Virginia School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist." While the article at Sciencedaily.com may be a bit breathlessly excited about it, even the more somber source article in Nature agrees that this "may call for a reassessment of basic assumptions in neuroimmunology"
"The patient tested negative for HIV, tuberculosis, lime disease, syphilis, coccidioides, histoplasma and cryptococcus." After four years of MRIs, a person's mysterious headaches, seizures and altered sense of smell and memory are diagnosed as a tapeworm growing throughout his brain.
You invest so much in it, don't you? It's what elevates you above the beasts of the field, it's what makes you special. Homo sapiens, you call yourself. Wise Man. Do you even know what it is, this consciousness you cite in your own exaltation? Do you even know what it's for?Dr. Peter Watts is no stranger to MetaFilter. But look past his sardonic nuptials, heartbreaking eulogies, and agonizing run-ins with fascists (and fasciitis) and you'll find one of the most brilliant, compelling, and disquieting science fiction authors at work today. A marine biologist skilled at deep background research, his acclaimed 2006 novel Blindsight [full text] -- a cerebral "first contact" tale led by a diverse crew of bleeding-edge post-humans -- is diamond-hard and deeply horrifying, wringing profound existential dread from such abstruse concepts as the Chinese Room, the Philosophical Zombie, Chernoff faces, and the myriad quirks and blind spots that haunt the human mind. But Blindsight's last, shattering insight is not the end of the story -- along with crew/ship/"Firefall" notes, a blackly funny in-universe lecture on resurrecting sociopathic vampirism (PDF - prev.), and a rigorously-cited (and spoiler-laden) reference section, tomorrow will see the release of
In a nutshell, this new study provides evidence that we need a certain amount of sleep every night, because the brain takes this time to rid itself of toxic metabolic byproducts, which would otherwise accumulate in the brain and impair brain function, destroy neurons — and potentially cause neurodegenerative disorders.
Is Psychometric g a Myth? - "As an online discussion about IQ or general intelligence grows longer, the probability of someone linking to statistician Cosma Shalizi's essay g, a Statistical Myth approaches 1. Usually the link is accompanied by an assertion to the effect that Shalizi offers a definitive refutation of the concept of general mental ability, or psychometric g." [more inside]
Chimp Fights and Trolley Rides from Radiolab's morality episode: "try to answer tough moral quandaries. The questions--which force you to decide between homicidal scenarios--are the same ones being asked by Dr. Joshua Greene. He'll tell us about using modern brain scanning techniques to take snapshots of the brain as it struggles to resolve these moral conflicts. And he'll describe what he sees in these images: quite literally, a battle taking place in the brain. It's 'inner chimp' versus a calculator-wielding rationale."
UC Berkeley researchers have successfully used functional Magnetic Resonance Imaging (fMRI) to decode and reconstruct people’s dynamic visual experiences - in this case, watching Hollywood movie trailers.
The Brain on Trial. Advances in brain science are calling into question the volition behind many criminal acts. A leading neuroscientist describes how the foundations of our criminal-justice system are beginning to crumble, and proposes a new way forward for law and order.
"We may someday find that many types of bad behavior have a basic biological explanation—as has happened with schizophrenia, epilepsy, depression, and mania."[more inside]
Swimming around in a mixture of language and matter, humans occupy a particular evolutionary niche mediated by something we call 'consciousness'. To Professor Nicholas Humphrey we're made up of "soul dust": "a kind of theatre... an entertainment which we put on for ourselves inside our own heads." But just as that theatre is directed by the relationship between language and matter, it is also undermined by it. It all depends how you think it.
"It is only fitting that the story of the brain should be a visual one, for the visuals had the ancients fooled for millenniums. The brain was so ugly that they assumed the mind must lie elsewhere. Now those same skeletal silhouettes glow plump and brightly colored, courtesy of a variety of inserted genes encoding fluorescent molecules. A glossy new art book, “Portraits of the Mind,” hopes to draw the general reader into neuroscience with the sheer beauty of its images." Slide Shows: The Beautiful Mind and Portraits of the Mind [more inside]
Ray Kurzweil: Reverse-Engineering of Human Brain Likely by 2030. PZ Myers: Ray Kurzweil does not understand the brain.
My Genome, My Self: Steven Pinker considers what we can expect from personal genomics. Searching for Intelligence in Our Genes: Carl Zimmer looks at the hunt to learn about the role of genes in intelligence.
Get your learn on. 180+ ways of investigating the human brain = hours of fun for the whole family. Thanks to an innocuous question by a 5 year old, my entire evening is now being spent investigating and discussing the structure and workings of the human brain. This flash site lets you explore the workings of the brain according to 12 subject areas (each with subtopics which are not included in the "180" count), within each of which are 5 levels of organization from social to molecular, within each of which are three levels of explanation (beginner, intermediate, and advanced.) discovered via Wikipedia.
Mapping the Structural Core of Human Cerebral Cortex. A new study of the connections in the brain has identified the brain's central hub.
"The Guardian has been granted exclusive and unfettered access to one of the most controversial research facilities at a British university." Caring or cruel? Inside the primate laboratory. Audio slideshow. A necessary evil - Colin Blakemore. Wise monkeys - Gill Langley.
Virtual Out-of-Body Experience. Using two procedures to deliberately scramble a person's visual and tactile senses, neuroscientists are able to induce "out-of-body" experiences in people. The effect is the same as the 'rubber hand illusion', but extends the effect to the whole body instead of just one limb (you can try the hand illusion for yourself).
Do You Taste What I Taste? - The first of Slate's 3-part series on the physiology of taste [parts 2, 3]
Sea Squirt Regrows Entire Body from One Blood Vessel. Most famous as the creature that settles down and eats its own brain (though that is not exactly correct), it appears the humble sea squirt has spectacular regenerative abilities as well, thanks to regeneration niches packed with stem cells. All glory to the sea squirt!
Dictionary of Disorder - shaping the DSM
Psychiatry by Prescription - Do psychotropic drugs blur the boundaries between illness and health?
Living with half a brain - hemispherectomy, probably the most radical procedure in neurosurgery
Blue Gene bears Blue Brain beats Deep Blue. Dr. Henry Markram answers questions in the FAQ. Neurons are beautiful. Blue Gene/L is now the fastest supercomputer in the world. IBM Research rocks. Deep Blue beat Kasparov almost a decade ago. Feeling Blue?
The first Transhuman Conference On the Law of Transhuman Persons: Whether or not you believe humans are set to evolve into gods, or AI is destined to achieve self-awareness the idea of the Transhuman is a thought provoking concept. Philosophers have debated the nature of the self, of the human for millennia. Is it time to start drafting new laws to govern all possible sentient beings on this planet? or is it all just a science of fiction? a comfortable humanist illusion?
Nature has a somewhat technical but free supplement on sleep
We are because of others. We are born into this world with minds as naked as our bodies and we have to rely on others to feed, clothe us, and to teach us to think of ourselves as selves. The key is language -- grammatical speech and human culture build upon the brain's biological capacities to create a mind that is something different again than that with which we are born. We are conscious because we can speak to others and ourselves, because we can speak of ourselves to others and ourselves. Language gives us as individuals, memory, and as groups, culture, the social memory. Or so thought Lev Semyonovich Vygotsky, among others. Welcome to the the neuronaut's guide to the science of consciousness.
Gene Prevents 'Brains Everywhere' The human version of the gene probably is not involved in keeping the human brain inside the skull, but likely plays some other role in nervous system development in human embryos, says Alejandro Sanchez Alvarado, a developmental biologist at the University of Utah School of Medicine. Cool.
The discovery of mirror neurons in the frontal lobes of monkeys, and their potential relevance to human brain evolution — which I speculate on in this essay — is the single most important "unreported" (or at least, unpublicized) story of the decade. I predict that mirror neurons will do for psychology what DNA did for biology: they will provide a unifying framework and help explain a host of mental abilities that have hitherto remained mysterious and inaccessible to experiments.
(after you read the essay, you might be interested in the responses.)
(after you read the essay, you might be interested in the responses.)