The Evolution of Bacteria on a “MEGA-Plate” Petri Dish - a cinematic approach to visualizing drug resistance
From deities to data - "For thousands of years humans believed that authority came from the gods. Then, during the modern era, humanism gradually shifted authority from deities to people... Now, a fresh shift is taking place. Just as divine authority was legitimised by religious mythologies, and human authority was legitimised by humanist ideologies, so high-tech gurus and Silicon Valley prophets are creating a new universal narrative that legitimises the authority of algorithms and Big Data." [more inside]
UCSD Chemistry Nobel laureate Roger Tsien dies. Amongst many other achievements, he is most well known as co-discoverer of Green Fluorescent Protein, which, as well as making headlines with glow-in-the dark rats, initiated a field that revolutionized biology and our understanding of the molecular and genetic basis of disease and life itself. More reaction and links from In The Pipeline. [more inside]
Nanowire Mesh Monitors Mouse Brains - "Injectable 'neural lace'* brain-computer interface works in mice for months at a time." (via) [more inside]
"She was born during the reign of James I, was a youngster when René Descartes set out his rules of thought and the great fire of London raged, saw out her adolescent years as George II ascended the throne, reached adulthood around the time that the American revolution kicked off, and lived through two world wars. Living to an estimated age of nearly 400 years, a female Greenland shark has set a new record for longevity, scientists have revealed." [more inside]
Vaults are large, barrel shaped protein complexes. Found in most eukaryotic cells, their exact function is currently unknown. [more inside]
Logic hacking - "Writing shorter and shorter computer programs for which it's unknowable whether these programs run forever, or stop... the winner of the Busy Beaver Game for N-state Turing machines becomes unknowable using ordinary math - somewhere between N = 5 and N = 1919." [more inside]
Genes that do the same thing in a human and a mouse are generally related by common descent from an ancestral gene in the first mammal. So by comparing their sequence of DNA letters, genes can be arranged in evolutionary family trees, a property that enabled Dr. Martin and his colleagues to assign the six million genes to a much smaller number of gene families. Of these, only 355 met their criteria for having probably originated in Luca, the joint ancestor of bacteria and archaea.Meet Luca, the Ancestor of All Living Things [more inside]
Biology textbooks tell us that lichens are alliances between two organisms—a fungus and an alga. They are wrong.
Alaska is Having Its Hottest Year Since Records Began - "After a spring that was a full ten degrees hotter than normal, the northern state is on track for the most sweltering year on record." (via) [more inside]
Return of the Cicadas is a short film by Samuel Orr about the insects' (surprisingly beautiful) 17-year lifespans. [more inside]
Let these chipper YouTube science vids fill you with existential terror. Popular YouTube education channels CGP Grey and Kurzgesagt teamed up to produce a pair of videos designed to cause you to question everything about your existence.
In his follow-up to Sapiens, Yuval Noah Harari envisions what a 'useless class' of humans might look like as AI advances and spreads - "I'm aware that these kinds of forecasts have been around for at least 200 years, from the beginning of the Industrial Revolution, and they never came true so far. It's basically the boy who cried wolf, but in the original story of the boy who cried wolf, in the end, the wolf actually comes, and I think that is true this time." [more inside]
How Technology Is Changing Our Hands by Darian Leader [The Guardian] Doctors predict that our increasing use of computers and mobile phones will permanently alter our hands. What will this mean for the way we touch, feel and communicate? [more inside]
Rafinesque (previously) was not known for his social graces; as John Jeremiah Sullivan writes, Audubon is the "only person on record" as actually liking him. During their visit, though, Audubon fed Rafinesque descriptions of American creatures, including 11 species of fish that never really existed. Rafinesque duly jotted them down in his notebook and later proffered those descriptions as evidence of new species. For 50 or so years, those 11 fish remained in the scientific record as real species, despite their very unusual features, including bulletproof (!) scales. Turns out we missed another 17 species that Audubon threw in there for fun.
Rafinesque’s “absurd” botanical legacy, Gray wrote, amounted to little more than a “curious mass of nonsense.” Gray’s note wouldn’t be the last unkind obituary in the annals of taxonomy, nor would it be the worst. That’s because the rules dictating how taxonomists name and classify living things bind these scientists in a web of influence stretching far back into the 18th century. When an agent of chaos like Rafinesque enters the scene, that web can get sticky fast. In a field haunted by ghosts, someone has to reckon with the dead.
The Cornell Lab of Ornithology BirdCast: Bird Migration Forecasts in Real-Time. When, where, and how far will birds migrate? Our migration forecasts will answer these questions for the first time.
Science is desperate. It needs to believe itself honorable. It's threatened by the fact that it's not safe for so many of us. Period. It's just not safe.- A. Hope Jahren, in an interview about women in science and advancement in plant biology.
The classification of Illinois's state fossil, the Tully monster, has been a mystery since its discovery in 1958. But now a team at Yale has determined that it is a vertebrate ancestor of the lamprey, after studying over a thousand fossils and noticing the presence of a notochord, among other distinctively vertebratey features. The (paywalled) Nature paper is here.
Transplantable human bone and cartilage made with 3D printer that creates a matrix in the desired shape and injects cells that can integrate with the patient's blood vessels on implant
Sexual harassment in science generally starts like this: A woman (she is a student, a technician, a professor) gets an email and notices that the subject line is a bit off: “I need to tell you,” or “my feelings.” The opening lines refer to the altered physical and mental state of the author: “It’s late and I can’t sleep” is a favorite, though “Maybe it’s the three glasses of cognac” is popular as well.
In the wake of the sequencing of the human genome in the early 2000s, genome pioneers and social scientists alike called for an end to the use of race as a variable in genetic research. Unfortunately, by some measures, the use of race as a biological category has increased in the postgenomic age. Although inconsistent definition and use has been a chief problem with the race concept, it has historically been used as a taxonomic categorization based on common hereditary traits (such as skin color) to elucidate the relationship between our ancestry and our genes. We believe the use of biological concepts of race in human genetic research—so disputed and so mired in confusion—is problematic at best and harmful at worst. It is time for biologists to find a better way. - An editorial in Science exploring the conundrum facing genomic researchers where race is both fundamentally flawed as a scientific model and violently dangerous but still the only consistent lens through which study participants understand the information they have about their own connection to human diversity [more inside]
Kept in the dark for 60 years, fruit flies begin to reveal their genetic adaptations. In 1954, seven years after their cousins returned from space, a colony of fruit flies was plunged into a darkness which would continue through 1500 generations right up till the present day. The results of this study shed considerable light on the role of genetic variation in physical adaptation. Spoiler: [more inside]
Vice Motherboard on the immortal jellyfish and Shin Kabota, the man who sings their praise. Shin Kubota music video.
Sleepy gorillas make their nests in Kahuzi-Biega National Park. You can visit these gorillas by going on a virtual gorilla trek in Democratic Republic of Congo!
One of the most beautiful, amazing, and depressing things I’ve ever done is participate in a whale necropsy. This work helps us understand the patterns of whale mortality, and determine whether whale deaths are natural, or possibly man-made. This is important stuff. In fact, their work has helped guide changes in policy, especially when it comes to designing the shipping lanes that go into and out of San Francisco Bay. Their research helped establish new, longer, and narrower shipping lanes that reduced the chances of ships hitting, and often killing, whales. This work saved whales’ lives. [more inside]
Creatures avoiding planks - "After around a thousand generations of training, the agents became half decent at avoiding planks. Please see the final result in this demo." [more inside]
Sure, we may be a little weird compared to our close relatives for not having a baculum (penis bone), and maybe that's the sort of thing you want to explain for whatever reason, but does human penis size and shape need a uniquely human story? Assuming it's correlated to the vagina like it probably is in many other species, then no it doesn't... unless the size and shape of the human vagina has an exceptional story. Does it? We wouldn't know. [more inside]
Humans 2.0 - "With CRISPR, scientists can change, delete, and replace genes in any animal, including us. Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis. One group has replaced a mutation that causes cataracts; another has destroyed receptors that H.I.V. uses to infiltrate our immune system." [more inside]
Sapiens: A Brief History of Humankind by Yuval Noah Harari - "The book delivers on its madly ambitious subtitle by in fact managing to cover key moments in the developmental history of humankind from the emergence of Homo Sapiens to today's developments in genetic engineering." Also btw, check out Harari on the myths we need to survive, re: fact/value distinctions and their interrelationships.
“Cut Microbe” is a sculpture entirely hand cut out of paper. Measuring 44 inches/112cms in length, it is half a million times bigger than the ecoli bacteria upon which it is based. I wanted to create a sculpture that reflected in the process of being made the incredible scale and complexity of this microbiological world. I am amazed at the strange beauty of the natural world and wanted to open people’s eyes to aspects of it that they rarely see. -Rogan Brown
The world's coral is suddenly and rapidly starting to die - "This is only the third time we've seen what we would refer to as a global bleaching event. [The prior events] were in 1998 and 2010, and those were pretty much one year events. We're looking at a similar spatial scale of bleaching across the globe, but spanning across at least 2 years. So that means a lot of these corals are being put under really prolonged stress, or are being hit 2 years in a row." Can 'manually breeding supercorals capable of living in increasingly inhospitable waters' help in time? (via/via)
A study published in the journal Animal Behavior found that crows can recognize their fellow dead crows and learn to avoid the dangerous circumstances associated with death. The BBC described the study, which involved a "masked individual playing bad cop, arriving on the scene holding up a dead crow." [more inside]
It's well understood that many species of parasitic wasp, when they lay their eggs on host caterpillars, also inject viruses that prevent the host's immune system from attacking the eggs. But it was recently discovered that some of those virus genes, as well as genes from parasitic wasps themselves, have become a part of the genome of some lepidopteran species (even protecting these species from a different type of virus), thus demonstrating horizontal gene transfer between insect species (link to paper).
Last night, Virginia Tech grad student Ann Hilborn, her labmate Chris Rowe, and their research supervisor Marcella Kelly were posting pictures of animal genitals on their lab’s Twitter account (@Whapavt). When Hilborn added some more from her collection, one of their readers called it a “junk-off”. And thus a hashtag was born. [NSFW?]
Since the pandas’ arrival, the team at Edinburgh zoo had already tried three times to breed the bears – with considerable fanfare and public attention – and each attempt had ended in disappointment. After a thoroughgoing review of these attempts in late 2014, this year’s season carried with it a sense of added pressure. But the keepers had also come up with one or two new tricks. A few weeks earlier, Maclean had daubed urine from Long Hui, an impressive male panda kept at Schönbrunn zoo, in Vienna, all over Yang Guang and Tian Tian’s enclosures, in order to spice the air with competition and possibility. “She spent a lot of time sniffing and seeing what was going on,” said Maclean. “He came out and was just like, ‘Whoa!’ He was all over the place.”
Spreading awareness of Artificially Selected Organisms. They have a Facebook page full of images sure to go viral, and even a White House petition. [This is satire.]
“In 1999, two Canadian astrophysicists, Stéphane Dumas and Yvan Dutil, composed and sent a message into space. The message was composed of twenty-three pages of bitmapped data, and was sent from the RT-70 radio telescope in Yevpatoria, Ukraine, as part of a set of messages called Cosmic Call.” [more inside]
Not all science is about going to Pluto, curing cancer, or ripping apart the fabric of the universe. Chris Buddle gives an object lesson in curiosity, passion and science for its own sake. [more inside]
"Accidentally glued myself to a crocodile while attaching a radio transmitter." The #fieldworkfail hashtag reveals the hilarious perils experienced by the Science side of Twitter.
"Humans as Superorganisms: How Microbes, Viruses, Imprinted Genes and Other Selfish Entities Shape Our Behavior" by Peter Kramer and Paola Bressan discusses the idea that an individual homo sapiens is only one component of the human superorganism we call a person, focusing on the psychological and psychiatric ramifications thereof. (Paola Bressan previously.)
Rosin Cerate is an "intensely researched blog" bringing you all kinds of interesting and odd knowledge about biology and creatures and how certain esoteric metals give you garlic breath. [via mefi projects] [more inside]
"Science, Chance, and Emotion with Real Cosima": A Longreads profile of Cosima Herter, the show's science consultant and the inspiration for Orphan Black's character Cosima. Mostly not directly about the show, but probably contains some spoilers if you're not fully caught up through season three.
"In a stunning discovery that overturns decades of textbook teaching, researchers at the University of Virginia School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist." While the article at Sciencedaily.com may be a bit breathlessly excited about it, even the more somber source article in Nature agrees that this "may call for a reassessment of basic assumptions in neuroimmunology"
Can evolution explain acts of kindness, and morality? [The Guardian]
We arranged a debate between a sceptical Tom Stoppard and the evolutionary biologist David Sloan Wilson. Stuart Jeffries acted as referee. We arranged for the two to meet recently in the grand boardroom of Wilson’s London publishers to discuss their differences, and reflect on two hard problems – what is the proper scope of science, and what is it to be human.
"The first 21 days of a bee's life in 60 seconds" is a time-lapse video by photographer Anand Varma, who discusses his collaboration with the bee lab at UC Davis in breeding a naturally mite-resistant line of honeybees. (Via.)
Scientists say they have reversed a bit of bird evolution in the lab and re-created a dinosaurlike snout in developing chickens.