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Dr. Arjun Srinivasan: We’ve Reached “The End of Antibiotics, Period”

For a long time, there have been newspaper stories and covers of magazines that talked about “The end of antibiotics, question mark?” Well, now I would say you can change the title to “The end of antibiotics, period.
posted by Memo on Oct 24, 2013 - 82 comments

"This is my gift to you. Do with it what you want."

The Course of Their Lives. While much in medicine has changed over the last century, the defining course of a first year medical student's education is still 'Gross Anatomy.' This is their hands-on tour of a donated cadaver -- an actual human body -- and is an experience which cannot be replicated by computer models. When Milwaukee Journal Sentinel reporter Mark Johnson came up with the idea of following a med school gross anatomy class for a feature story, his editor challenged him to make it different. So he chose to intertwine the students' stories with that of Geraldine 'Nana' Fotsch, a living future donor, as sort of a stand-in for the cadaver. (Via. This four-part series contains descriptions of a human dissection. Some may find it disturbing.) [more inside]
posted by zarq on Oct 19, 2013 - 29 comments

Why Sleep Deprivation Can Destroy You

In a nutshell, this new study provides evidence that we need a certain amount of sleep every night, because the brain takes this time to rid itself of toxic metabolic byproducts, which would otherwise accumulate in the brain and impair brain function, destroy neurons — and potentially cause neurodegenerative disorders.
posted by Brandon Blatcher on Oct 19, 2013 - 87 comments

Telephone

A study [PDF] by CUNY Professor Diana Reiss and Rachel Morrison (Biopsychology and Behavioral Neuroscience Subprogram in Psychology The Graduate Center of CUNY) was published last week in Zoo Biology detailing for the first time a whisper‐like behavior in a non‐human primate, the cotton top tamarin at the Central Park Zoo. [more inside]
posted by roomthreeseventeen on Sep 21, 2013 - 8 comments

Explain DNA to me like I’m a twelve-year-old

"Read this carefully so that you understand it. When you come home we will show you the model. Lots of love, Daddy." In 1953 Francis Crick, sat down to write his twelve-year-old son Michael a letter explaining his brand-new discovery: the double-helix structure of DNA. Now you can read the original, seven-page hand-written letter, complete with an interactive feature that lets you click for details, context and explanations. Courtesy of the Smithsonian. [more inside]
posted by evilmomlady on Sep 13, 2013 - 18 comments

Geared for jumping

Intermeshing, rotating mechanical gears have been found in an insect. The gears act to ensure that the legs of the hopping insect move at the same rate when jumping, and are lost during molting to an adult stage. Via reddit, where the journalist is participating. Science magazine report (paywalled).
posted by exogenous on Sep 13, 2013 - 52 comments

Being a fair sport

In athletic competitions, what qualifies as a sporting chance?
posted by Gyan on Sep 4, 2013 - 41 comments

Becoming "Cliterate"

Teaching Cliteracy 101: "It is a curious dilemma to observe the paradox that on the one hand the female body is the primary metaphor for sexuality, its use saturates advertising, art and the mainstream erotic imaginary. Yet, the clitoris, the true female sexual organ, is virtually invisible." ~ Artist Sophia Wallace is using street art and an art exhibition that incorporates pithy slogans, 'scientific data, historical information as well as references to architecture, porn, pop culture and human rights' to make "the case for the clit". (Links throughout this post may be NSFW.) [more inside]
posted by zarq on Aug 30, 2013 - 57 comments

The intersection of parasitism and philosophy

The Thoreau Poison - Caleb Crain of The New Yorker takes a closer look at the ideas explored in Upstream Color (spoilers)
posted by Blazecock Pileon on Aug 16, 2013 - 19 comments

LET’S LEARN ABOUT CATS

CATS? WHAT THEY ARE AND HOW THEY GOT DOMESTICATED (MAYBE??) A TUMBLR ESSAY
posted by The Whelk on Aug 10, 2013 - 52 comments

Wizarding Genetics

"I sent this paper to JK Rowling explaining how the wizarding gene could be singular, autosomal, and dominant despite the protests of a bunch of fans who stopped learning genetics after Punnett squares." See also: Wizarding Genetics: More Complicated Than Mendel! and Purple Orchids and Muggleborn Wizards: A Theory of Wizard Genetics
posted by Memo on Jul 30, 2013 - 57 comments

Mouseunculus

Mouseunculus: How The Brain Draws A Little You. [Via]
posted by homunculus on Jul 25, 2013 - 16 comments

Ovaries! Time MAchines!

British comedian Josie Long explores All the Planet's Wonders in a very short series on BBC radio: Collecting. Animals. Astronomy. Plants.
posted by 1f2frfbf on Jul 8, 2013 - 11 comments

Mouse cloned from drop of blood

Scientists in Japan have cloned a mouse from a single drop of blood. (via)
posted by kliuless on Jun 30, 2013 - 33 comments

Computer model shows men to blame for menopause

Men to Blame for Menopause: Younger Women Preferred in Human Evolutionary History. Humans are actually the only species where females cannot reproduce throughout their lives, and previous studies have suggested that there may be a "grandmother effect." This suggests that women lose their fertility at an age where they may not live to care for another child. Instead, they're available to care for younger women's children. Yet some scientists weren't satisfied with this theory. "How do you evolve infertility? It is contrary to the whole notion of natural selection" ... Original paper published in PLOS Computational Biology - Mate Choice and the Origin of Menopause [more inside]
posted by Golden Eternity on Jun 14, 2013 - 68 comments

"He needs to be a Youtube star."

Oliver the green moray eel loves to be petted. With small children, a fish popsicle, and commentary about barracudas. (SLYT) [more inside]
posted by casarkos on Jun 13, 2013 - 35 comments

Next step: uploaded lobsters in space

"OpenWorm is an attempt to build a complete cellular-level simulation of the nematode worm Caenorhabditis elegans. Of the 959 cells in the hermaphrodite, 302 are neurons and 95 are muscle cells. The simulation will model electrical activity in all the muscles and neurons. An integrated soft-body physics simulation will also model body movement and physical forces within the worm and from its environment." -- Bonus: explore the worm's cellular anatomy in 3D (WebGL required.)
posted by MartinWisse on Jun 3, 2013 - 16 comments

Here comes a tall, thin, yellow human!

After more than 25 years of studying the calls of prairie dog in the field, one researcher managed to decode just what these animals are saying. And the results show that prairie dogs aren't only extremely effective communicators, they also pay close attention to detail.
posted by cthuljew on Jun 2, 2013 - 33 comments

Olympus Microscopy Resource Center digital video gallery

The Olympus Microscopy Resource Center digital video gallery, with: live cells, pond life and more, crystals and more.
posted by Blazecock Pileon on May 29, 2013 - 4 comments

One genome, two plants

Mosses Make Two Different Plants From the Same Genome, and a Single Gene Can Make the Difference
One of the most astonishing secrets in biology is this: every plant you see makes two different plants from the same genome. And, scientists recently reported, a single gene from an ancient, powerful lineage can make the difference.

posted by Joe in Australia on May 12, 2013 - 24 comments

Using Game Theory to Teach Game Theory

Peter Nonacs, a professor at UCLA, let his students cheat on an exam he called "impossibly difficult", saying, "Let’s see what you can accomplish when you have no restrictions."
posted by boo_radley on May 6, 2013 - 32 comments

DNA Lab Party at 4 PM: Staph only!

Celebrate the 60th anniversary of the discovery of DNA's structure with a pictorial story behind DNA's double helix and the Rosalind Franklin papers, including correspondences and lab notes that detail some of her crystallography research, findings that laid the groundwork for Watson and Crick's later publication.
posted by Blazecock Pileon on Apr 25, 2013 - 6 comments

Fruit Flies at the Whole Foods

"Is organic produce better for you?" is a simple question asked by a middle schooler in a science fair. Using fruit flies fed organic vs. conventional produce, Ria Chhabra tracked the flies and saw improvements based on their diet. Now barely a sophomore in high school, the project lead to university research labs, science fair awards, publication in top-tier peer-reviewed journals, and quite likely, scholarships at her pick of top-flight universities.
posted by mathowie on Apr 18, 2013 - 90 comments

Gene genie, let yourself go

After a decade or so of legal back-and-forth between Utah-based Myriad Genetics and medical researchers, the ACLU, and the Public Patent Forum, the US Supreme Court will hear a case next week which attempts to address whether genes — isolated (derivative) or original — can be patented. The stakes are high on both sides: opponents use Myriad's actions to argue that giving short-term monopoly control over humanity's genetic constituency is not in the public interest, while proponents defend the use of patents to spur private research in biotech, alternative energy and other nascent industries.
posted by Blazecock Pileon on Apr 12, 2013 - 58 comments

Intelligence Tests

Is Psychometric g a Myth? - "As an online discussion about IQ or general intelligence grows longer, the probability of someone linking to statistician Cosma Shalizi's essay g, a Statistical Myth approaches 1. Usually the link is accompanied by an assertion to the effect that Shalizi offers a definitive refutation of the concept of general mental ability, or psychometric g." [more inside]
posted by kliuless on Apr 11, 2013 - 113 comments

Silicon-based viruses of the analog kind

A selection of glass viruses by artist Luke Jerram (a full gallery and photographs of other sculptural work are also available directly from his site)
posted by Blazecock Pileon on Apr 9, 2013 - 9 comments

Selection pressure

Researchers have found that size does matter as it relates to overall proportions of the male body (PNAS link, PDF)
posted by Blazecock Pileon on Apr 8, 2013 - 233 comments

BRRRAAAIIIIINNNNSSSS!!!

Pictures of some brains from the Texas State Mental Hospital. (Not for the squemish.) "I walked into a storage closet filled with approximately one-hundred human brains, none of them normal, taken from patients at the Texas State Mental Hospital. The brains sat in large jars of fluid, each labeled with a date of death or autopsy, a brief description in Latin, and a case number."
posted by OmieWise on Apr 5, 2013 - 35 comments

A possible souce for the "fairy circles" in Africa

In temperate climates, "fairy rings" appear in grassy meadows and lawns, and these are caused by fungi, with some rings expanding for hundreds of years. But in the western part of Southern Africa, there are a different sort of "fairy circles," barren circles that are surrounded by long-lived perennial grasses. The Himba people, an ethnic group in northern Namibia, attribute them to original ancestor, Mukuru, or consider them "footprints of the gods," and scientists have been stumped for decades. Professor Norbert Jürgens, from the University of Hamburg, might have finally solved the riddle: a species of termites that are most active at night and don't build big, noticeable nests, have engineered the ecosystem by eating the roots of grasses that grow within the circle, keeping the soil moist for long periods of time. The discussion continues, as some scientists who have studied the phenomena aren't so sure about the theory.
posted by filthy light thief on Mar 29, 2013 - 5 comments

Evolution: Maybe It's Not Just for the Fittest Anymore

Is it time to put natural selection in its place? Jello Biafra once famously wrote that "If evolution is outlawed, only outlaws will evolve." But while it likely comes as no surprise to specialists working in the field or to those who've been following developments in evolutionary biology closely, there's an emerging view among experts that Darwin's view of natural selection as the primary driver of speciation and evolutionary change may be incorrect or at least drastically overstated. It's long been understood that non-adaptive evolutionary mechanisms like "genetic drift" and random mutation also play non-trivial roles in evolutionary processes, but a recent study (link to abstract with full-text PDF available) casts new doubts on the primary role of natural selection, finding that "Neutral models, in which genetic change arises through random variation without fitness differences have proven remarkably successful in describing observed patterns of biodiversity." [more inside]
posted by saulgoodman on Mar 28, 2013 - 51 comments

Secret Universe

The Hidden Life Of the Cell (57:24) There is a battle playing out inside your body right now. It started billions of years ago and it is still being fought in every one of us every minute of every day. It is the story of a viral infection - the battle for the cell. This film reveals the exquisite machinery of the human cell system from within the inner world of the cell itself - from the frenetic membrane surface that acts as a security system for everything passing in and out of the cell, the dynamic highways that transport cargo across the cell and the remarkable turbines that power the whole cellular world to the amazing nucleus housing DNA and the construction of thousands of different proteins all with unique tasks. The virus intends to commandeer this system to one selfish end: to make more viruses. And they will stop at nothing to achieve their goal. Exploring the very latest ideas about the evolution of life on earth and the bio-chemical processes at the heart of every one of us, and revealing a world smaller than it is possible to comprehend, in a story large enough to fill the biggest imaginations.
You may be familiar with molecular movies from my two previous megaposts collecting them, but this extended documentary uses original animation that is collected into a coherent educational narrative and is just so fucking gorgeous. Enjoy.
[more inside]
posted by Blasdelb on Mar 24, 2013 - 20 comments

Living In Science Fiction: 2013 Edition

Science Fiction Comes Alive as Researchers Grow Organs in Lab
1997 -- Charles Vacanti of University of Massachusetts Medical Center and Robert Langer of Massachusetts Institute of Technology report the growing of a cartilage structure – in the shape of a human ear – on a mouse’s back. 2008 -- Doris Taylor at the University of Minnesota and colleagues grow a beating rat heart in the lab. 2008 --Surgeons in Spain transplant a new windpipe into a patient. The organ is made from a cadaver windpipe stripped of its original cells and reseeded with the patient’s own cells. 2010 -- Researchers at Mass General Hospital grow a rat liver. 2010 -- Yale University scientists grow a functioning rat lung. 2010 -- Alex Seifalian in London transplants a lab-made tear duct into patient 2011 -- Dr. Seifalian makes a windpipe from nanocomposite materials plus a patient’s own stem cells; the new windpipe replaces the patient’s cancerous one, saving his life. In a separate procedure, an artery made at Dr. Seifalian’s lab is transplanted into a patient. 2012 -- Surgeons in Sweden transplant a major blood vessel into a 10-year-old girl. The vein was taken from a dead man, stripped of its tissue, then reseeded with the girl’s own cells. 2013 -- Scientists from Cornell University report the making of a human ear using living cartilage cells.

posted by jason's_planet on Mar 23, 2013 - 22 comments

Better, stronger, faster kidneys.

What do 3D printing, jelly, liver transplants, chainmail, dental fillings, ferrofluids, and the Six Million Dollar man have to tell us about our future? Materials scientist and engineer Mark Miodownik lets us know in this Royal Institution lecture.
posted by cthuljew on Mar 22, 2013 - 8 comments

Nagel on the Materialist Neo-Darwinian Conception of Nature

Andrew Ferguson explains and defends eminent philosopher Thomas Nagel, who has been stirring up outraged refutations (e.g. here or here) with his new book Mind and Cosmos: Why the Materialist Neo-Darwinian Conception of Nature Is Almost Certainly False. Also in the defense column is philosopher Edward Feser's extensive series on Nagel's book.
posted by shivohum on Mar 19, 2013 - 163 comments

sea & sky

seaQuest: what if we could learn to live on/underneath the oceans (or in orbit)? [previously(er)] [more inside]
posted by kliuless on Mar 18, 2013 - 14 comments

Tony Stark, eat your heart out.

Defense contractor takes break from F-35 JSF, finds a way to eliminate 99% of the energy cost of desalination. Lockheed-Martin has developed a way to craft sheets of carbon a single atom thick, which can filter the salt (and just about anything else) from water with a tiny fraction of the energy required by current processes. "Lockheed officials see other applications for Perforene as well, from dialysis in healthcare to cleaning chemicals from the water used in hydraulic fracturing, or "fracking," of oil and gas wells." Previously.
posted by Morriscat on Mar 15, 2013 - 67 comments

"Everyone loves owls. Even mammalogists love owls."

Why are owls so wise? Perhaps it's because they're utter badasses.
Ferocity is essential for a bird whose frigid, spotty range extends across northeastern China, the Russian Far East and up toward the Arctic Circle, one that breeds and nests in the dead of winter, perched atop a giant cottonwood or elm tree, out in the open, in temperatures 30 degrees below zero Fahrenheit. Dr. Slaght’s colleague Sergei Surmach videotaped a female sitting on her nest during a blizzard. “All you could see at the end was her tail jutting out,” Dr. Slaght said.
The New York Times Science section gives an update on some current owl research. [more inside]
posted by medusa on Feb 28, 2013 - 46 comments

Links To The Damn Paper

Hello and welcome to Links to the Damn Paper, an open discussion community showcasing the best in freely-available biology research. If you’ve ever tried to have a discussion about science on the Web and been stymied and frustrated by inaccessible articles, misrepresentation of research in science journalism, or a community that seems uninterested in digging into the actual research behind a topic, then welcome: you are our people. If you’ve ever wished for a place to talk about the Science of Life where you could be sure that the actual articles were available, where compelling research was presented in a way that allowed it to speak for itself, and where you could discuss science with actual scientists and with other people who are passionate about science for its own sake, then you have found your haven.
MeFi's own Blasdelb, ChuraChura, and Scientist have G(T)OB. And it is good. [via mefi projects]
posted by you must supply a verb on Feb 19, 2013 - 53 comments

Single Molecule Determines Complex Behavior, Say Scientists

Single Molecule Determines Complex Behavior, Say Scientists.
posted by escabeche on Feb 10, 2013 - 22 comments

iBioSeminars

iBioSeminars - "Bringing the World's Best Biology To You" [more inside]
posted by Blazecock Pileon on Feb 9, 2013 - 5 comments

Twelve Mintue Chunks Of White Hot Knowledge!

John And Hank Green (previously), amusing youtube teachers of world history and biology have finished the first cycle of their educational series Crash Course (previously) and have wrapped up mini lessons on Literature and Ecology. Now they've just started two brand new series on U.S History and Chemistry (to come). Outtakes.
posted by The Whelk on Feb 6, 2013 - 19 comments

"Quantum biology: Do weird physics effects abound in nature?"

Quantum Biology - Disappearing in one place and reappearing in another. Being in two places at once. Communicating information seemingly faster than the speed of light. This kind of weird behaviour is commonplace in dark, still laboratories studying the branch of physics called quantum mechanics, but what might it have to do with fresh flowers, migrating birds, and the smell of rotten eggs? More: Quantum smell' idea gains ground Both BBC.
posted by marienbad on Jan 28, 2013 - 59 comments

CIL-CCDB

A curated repository of cellular microscopy data [more inside]
posted by Blazecock Pileon on Jan 19, 2013 - 2 comments

A pelican that looks like a urinal

Go home, evolution, you're drunk. A photo of a pelican that looks like a urinal. Brought to you by WTF, Evolution?
posted by escabeche on Jan 16, 2013 - 54 comments

Undue Burden

Jennie Linn McCormack "isn’t the only woman in recent years to be prosecuted for ending her own pregnancy. But her case could change the trajectory of abortion law in the United States": The Rise of DIY Abortions. [more inside]
posted by zarq on Jan 3, 2013 - 66 comments

Artistic SeaSnails build other shells into their shells SL

Artistic SeaSnails build other shells into their shells SL
posted by maiamaia on Dec 31, 2012 - 28 comments

State of Nature

“When I spoke at the two Ron Paul events in Tampa, a young man kind enough to pick me up at the airport told me a fascinating story. The vast majority of young Ron volunteers in offices he visited all over the country were paleo. If a kid ordered pizza — which was always the primary or perhaps only campaign food — he was practically booed,” Atossa Araxia Abrahamian writes in The New Inquiry about the paleo diet, libertarianism, and the appealing idea of a healthy, undistorted state of nature to which we can return if we are only pure enough. [more inside]
posted by escabeche on Dec 29, 2012 - 208 comments

On Barflies and Fruit Flies

Promiscuous Males And Choosy Females? While previous studies have poked holes in Bateman's classic experiment, a recent study reveals fundamental methodological flaws. PDF slides with an excellent explanation.
posted by stp123 on Dec 15, 2012 - 56 comments

Make love, not war.

Humon's illustrated (and explained) animal mating habits. [somewhat NSFW]
posted by cthuljew on Dec 15, 2012 - 15 comments

291 diseases and injuries + 67 risk factors + 1,160 non-fatal complications = 650 million estimates of how we age, sicken, and die

As humans live longer, what ails us isn't necessarily what kills us: five data visualizations of how we age, sicken, and die. Causes of death by age, sex, region, and year. Heat map of leading causes and risks by region. Changes in leading causes and risks between 1990 and 2010. Healthy years lost to disability vs. life expectancy in 1990 and 2010. Uncertainties of causes and risks. From the team for the massive Institute for Health Metrics and Evaluation Global Burden of Diseases, Injuries, and Risk Factors Study 2010. [more inside]
posted by hat on Dec 14, 2012 - 11 comments

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