Maia Szalavitz [mefi's own maias] talks about her new book, Unbroken Brain: A Revolutionary New Way of Understanding Addiction on Fresh Air with Terry Gross (transcript) - "We have this idea that if we are just cruel enough and mean enough and tough enough to people with addiction, that they will suddenly wake up and stop, and that is not the case."
Magic Mushroom Drug Lifts Depression in Human Trial - "The findings show that more research in this field is now needed. 'This is the first time that psilocybin has been investigated as a potential treatment for major depression', says lead author Dr Robin Carhart-Harris, Imperial College London."
How Tripping On Mushrooms Changes The Brain - "New research [pdf] suggests that psilocybin, the main psychoactive ingredient in magic mushrooms, sprouts new links across previously disconnected brain regions, temporarily altering the brain's entire organizational framework." [more inside]
Based on a comparison of suicide rates at sea level and at areas above 2,000 feet, living at a high altitude may make people 30% more likely to commit suicide. Neuroscientist Perry Renshaw believes that it's due to the impact of altitude on the brain.
Why the bacteria in food like yogurt may be the answer to anxiety and depression. Probiotic-rich food is good for your gut, but it may also be good for your brain, say researchers.
From the mid 40s to the mid 50s Coronet Instructional Films were always ready to provide social guidance for teenagers on subjects as diverse as dating, popularity, preparing for being drafted, and shyness, as well as to children on following the law, the value of quietness in school, and appreciating our parents. They also provided education on topics such as the connection between attitudes and health, what kind of people live in America, how to keep a job, supervising women workers, the nature of capitalism, and the plantation System in Southern life. Inside is an annotated collection of all 86 of the complete Coronet films in the Prelinger Archives as well as a few more. Its not like you had work to do or anything right? [more inside]
Falling STAR*D?: It is common practice for psychiatrists to switch depressive patients between different antidepressants if their current drug does not evince a symptomatic response. Despite clinical wisdom supporting this, little empirical, controlled evidence exists to direct “switching” protocols (e.g. if a patient with Z characteristics is on drug X, is it usually better to switch to drug A, B, or C? Will switching help at all?) in the psychopharmacological treatment of depression. The NIMH-funded STAR*D (Sequenced Alternatives to Relieve Depression) study aimed to address these questions of treatment direction in a very large (n>4000), “real-world” sample using a multi-phase treatment plan with different drugs (and cognitive therapy) at every step to maximize chances of eventual remission. Overall, the NIMH reported that about 67% of patients eventually achieved remission, with few differences in effectiveness between different types of treatment at each step. However, researchers and commentators have raised concerns regarding inconsistent reporting of outcomes, after-the-fact changes in study design and analysis, and other issues that may have inflated, partially invalidated, or misrepresented widely reported treatment outcomes. These inequities may also have implications for the secondary moderator analyses (i.e. does trait A predict switching to X or Y is better?) that were a major reason for the study. [more inside]
The epidemic of mental illness plaguing the Americans and the overmedication of psychiatric patients are in part artifacts of the diagnostic method. [more inside]
More research into into the effects of ketamine on depression published today in the journal Science [abstract]. [more inside]
A review of the current state of gender based brain research shows that women and men differ both in the way their brains are constructed and in how they function.
..correlation between brain region size in adults and sex steroid action in utero suggests that at least some sex differences in cognitive function do not result from cultural influences or the hormonal changes associated with puberty--they are there from birth.Treatment for such things as schizophrenia and depression will likely have gender specific variations in the future. Previously, brain research that examined gender differences was considered controversial because it was argued that the results might give rise to more sex discrimination against women. That view may be changing.
Anxious? Depressed? - you need more brain cells. Just take one of these twice a day. New research shows that antidepressants may not work as we thought at all, rather they actually stimulate growth of cells in the hippocampus area of the brain. This may all be for the good - but it seems strange that we release millions of happy pills and market them as safe without knowing for sure what they do. Perhaps its the money talking.
"It Did It" is a beautiful and haunting short flick about depression. Peter Brinson artfully uses the Scientific Method to creatively document the effects of the drug Zoloft on his mood and his brain chemistry.
New treatment for depression in women possibly best news ever for men.
When you reach an error page on this manic-depressive server's site, you get some very interesting results. This is not your typical 404, it's a whole lot more.