New Ebola vaccine shows 100% success rate in clinical trial. Today the World Health Organization has announced that the rVSV-ZEBOV vaccine had a 100% success rate in preventing onset of the disease if administered within 10 days of exposure (n=4,000). In response to the current outbreak in West Africa that has afflicted over 27,000 and killed over 11,000, this collaborative effort led by the WHO pushed the vaccine through a process that usually takes more than a decade in just 12 months. Official paper from The Lancet here (pdf).
Ebola is nightmare fuel: a biological doomsday device conspiring with our bodies to murder us in uniquely gruesome fashion. It’s also killed fewer than 2,000 people. How has a virus with such a modest body count so fiercely captured the darkest corners of our imagination? - Leigh Cowart for Haziltt.
There's been an ebola outbreak in Guinea, Liberia, and Sierra Leone. With 122 cases so far, this is the worst outbreak since 2007's 264-case outbreak. The worst outbreak was 2000-2001's 425 cases. What makes this one different is the way it has spread so widely. [more inside]
A new malaria vaccine has been shown effective in large-scale field trials. After decades of disappointment, researchers think they're finally on track to unleash the first practical vaccine against malaria, one of mankind's ancient scourges. In the world's first large field trial of an experimental malaria vaccine, several thousand young children who got three doses had about 55 percent less risk of getting the disease over a year than those who got a control vaccine against rabies or meningitis. [more inside]
AIDS really did come from chimps in the 1950s --..."We're 25 years into this pandemic," Hahn said. "We don't have a cure. We don't have a vaccine. But we know where it came from. At least we can make a check mark on one of those." ... ...Identifying the source of the HIV pandemic is more than filling in a missing link in the disease's progression. ...
Ascaris lumbricoides. According to estimates, about 1.5 billion people--about a quarter of the earth's population--are hosts to the Ascaris lumbricoides parasitic worm. Ascaris worms can grow to be 18 inches in length, and use their host's windpipe and esophagus to migrate between the small intestine and the lungs. A single human host may support dozen of large worms, which can be contracted by contact with fecal matter, animals, or undercooked pork. Under some circumstances (the worms dislike anesthesia, for example) one or more worms may exit from the mouth (a horrifying image), or the anus (one of the most disgusting images I have ever seen, and not safe for work, obviously). Here, the removal of a worm is caught on video (Realplayer). Too disgusting to post? Almost. But 1.5 billion people have got these in their bodies right now. That's what's grosser than gross.
Is circumcision an AIDS weapon? To cut or not to cut? Does circumcision prevent the transmission of HIV? It was deemed "An acceptable strategy for HIV prevention" in Bostwana and a study looking at the magnitude of females who get infected with HIV/AIDS/STDs through circumcision