New Ebola vaccine shows 100% success rate in clinical trial. Today the World Health Organization has announced that the rVSV-ZEBOV vaccine had a 100% success rate in preventing onset of the disease if administered within 10 days of exposure (n=4,000). In response to the current outbreak in West Africa that has afflicted over 27,000 and killed over 11,000, this collaborative effort led by the WHO pushed the vaccine through a process that usually takes more than a decade in just 12 months. Official paper from The Lancet here (pdf).
On April 29 the World Health organization declared North and South America to be free of rubella after the last reported endemic case in Argentina in 2009. The New York Times discusses the history of rubella eradication in the Americas and the case of Gene Tierney, an actress who caught the disease while performing a show in 1943.
The Illusion of "Natural": In an excerpt from her new book On Immunity, Eula Biss deconstructs desires to flee from "toxins" and embrace what is "natural". Where the word filth once suggested, with its moralist air, the evils of the flesh, the word toxic now condemns the chemical evils of our industrial world. This is not to say that concerns over environmental pollution are not justified—like filth theory, toxicity theory is anchored in legitimate dangers—but that the way we think about toxicity bears some resemblance to the way we once thought about filth. [more inside]
A new malaria vaccine has been shown effective in large-scale field trials. After decades of disappointment, researchers think they're finally on track to unleash the first practical vaccine against malaria, one of mankind's ancient scourges. In the world's first large field trial of an experimental malaria vaccine, several thousand young children who got three doses had about 55 percent less risk of getting the disease over a year than those who got a control vaccine against rabies or meningitis. [more inside]
AIDS really did come from chimps in the 1950s --..."We're 25 years into this pandemic," Hahn said. "We don't have a cure. We don't have a vaccine. But we know where it came from. At least we can make a check mark on one of those." ... ...Identifying the source of the HIV pandemic is more than filling in a missing link in the disease's progression. ...
Another year, another flu vaccine shortage. Perhaps it just the first salvo of 2004's media Flu Frenzy! I think this winter I will retire the the TV, forget about my pharma portfolio and instead light a fire, swig some hot lemon and honey tea, and spice up my life.
First Documented Case of HIV hybridization in a human being was presented at the International AIDS Society conference in Paris. In this case, genetic tests on a superinfected woman showed that the two strains she was infected with swapped genetic material, creating a new hybrid strain of HIV. The actual effects are not yet clear, but this could pose a serious problem for researchers trying to create a vaccine.
They're ugly. I mean small and really ugly! And they don't do us any favors at all. We can hold each other's hands, and share support. Our fight against them may lead to knowledge in other battles, but I think its time to go on the offensive. Its time to defang the beastie. (Maybe I should have posted this at Warfilter instead?)