Inside the insectary - "These gene drives, they're able to copy themselves. So instead of half of the offspring inheriting the gene drive, almost all of them do. So what happens is that it spreads and it spreads and it spreads. And this is the fantastic thing. Because it allows that gene to be selfish in a population. And in a very short amount of time you can actually transform an entire wild population into a modified population. It's powerful." (previously: 1,2,3)
Nanowire Mesh Monitors Mouse Brains - "Injectable 'neural lace'* brain-computer interface works in mice for months at a time." (via) [more inside]
Humans 2.0 - "With CRISPR, scientists can change, delete, and replace genes in any animal, including us. Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis. One group has replaced a mutation that causes cataracts; another has destroyed receptors that H.I.V. uses to infiltrate our immune system." [more inside]
The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
Norbert Wiener: The Eccentric Genius Whose Time May Have Finally Come (Again) - "The most direct reason for Wiener's fall to relative obscurity was the breakthrough of a young mathematician and engineer named Claude Shannon." [more inside]
Recently Emily Graslie, of the fantastic natural history tumblr and youtube series TheBrainScoop, was asked a question about whether she had personally experienced sexism in her field. Her response is fucking amazing.
Inside is her goldmine of awesome female science educators online with channels that focus on Science Technology Engineering and Math. My work day is fucked.[more inside]
"Algae is the ultimate biological system using sunlight to capture and convert carbon dioxide into fuel... I came up with a notion to trick algae into pumping more [fuel] out." Craig Venter's Synthetic Genomics partners with ExxonMobil in a $600M project to harvest biofuels from genetically engineered algae. "We have modest goals of replacing the whole petrochemical industry." [previously] [more inside]
Imagine nature's most elegant ideas organized by design and engineering function, so you can enter "filter salt from water" and see how mangroves, penguins, and shorebirds desalinate without fossil fuels. That's the idea behind AskNature, the online inspiration source for the biomimicry community. The featured pages are a good starting point. Cross-pollinating biology with design. [more inside]
Prof Lakshminarayanan Mahadevan looks at the physics of wrinkles, creases and folds - from the small to the very large (video demos), feeds his venus flytrap, then rides on his magic carpet.
More than Human - Ramez Naam's site promoting his new book (about emerging technologies for engineering human biology, more or less), has excerpts, a list of upcoming appearances, and even a full-fledged blog linking to articles and commentary that might be of interest to people curious about the book's transhumanist ideas. Now this is the way to do it.