Humans 2.0 - "With CRISPR, scientists can change, delete, and replace genes in any animal, including us. Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis. One group has replaced a mutation that causes cataracts; another has destroyed receptors that H.I.V. uses to infiltrate our immune system." [more inside]
The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
The annual James Dyson Award is open to current and recent design engineering students. The winner this year is James Roberts with his inflatable incubator MOM. The device costs around £250 compared to £30,000 for modern incubators and could prevent up to 75% of fatalities in premature birth cases in the developing world.
The 2013 Lasker Awards were announced today. Often called the "American's Nobels", they recognize the contributions of scientists, physicians, and public servants who have made major advances in the understanding, diagnosis, treatment, cure, and prevention of human disease. Included in today's crop of recipients are Dr. Graeme M. Clark, Dr. Ingeborg Hochmair, and Blake S. Wilson who were awarded their prizes for developing the modern cochlear implant. [more inside]
Neurosecurity: security and privacy for neural devices. "An increasing number of neural implantable devices will become available in the near future due to advances in neural engineering. This discipline holds the potential to improve many patients' lives dramatically by offering improved—and in some cases entirely new—forms of rehabilitation for conditions ranging from missing limbs to degenerative cognitive diseases. The use of standard engineering practices, medical trials, and neuroethical evaluations during the design process can create systems that are safe and that follow ethical guidelines; unfortunately, none of these disciplines currently ensure that neural devices are robust against adversarial entities trying to exploit these devices to alter, block, or eavesdrop on neural signals. The authors define 'neurosecurity'—a version of computer science security principles and methods applied to neural engineering—and discuss why neurosecurity should be a critical consideration in the design of future neural devices." [Via Mind Hacks]
Seven hot technologies that we'll soon see on the market, according to MIT's Tech Review magazine. The spam blocker sounds like it might work. But the babelfish?