MetaFilter posts tagged with genetics and medicine

Do they preserve scientific transparency, protect profits or both?

zarq — Wed, 13 May 2009 10:16:38 -0800

On behalf of medical organizations, universities, & individual patients, pathologists and genetics researchers, the ACLU has filed a lawsuit against Utah-based Myriad Genetics and the US Patent and Trademark Office. Myriad holds the US patents to the BRCA1 and BRCA2 genes, associated with hereditary causes of breast and ovarian cancers. Their patents guarantee the company the right to prevent anyone else from testing or studying those genes, which the ACLU says is unconstitutional and inhibits researchers from finding treatments and cures. The ACLU has posted a FAQ explaining the suit. It might be news to some that genes, gene fragments and the tools used to assess them can be patented. Here's some general info on patent eligibility and qualifications. Some question whether such patents spur or stifle research Myriad's BRCA test to measure the likelihood that someone would develop ovarian or breast cancer was in the news a couple of years ago, when a study revealed that it produces false negatives. Concerns were also raised in the EU over the patents when they were initially filed. Previously on MeFi

retrovirally transforming pancreatic cells from adult mice into insulin-producing beta cells

kliuless — Wed, 27 Aug 2008 19:51:39 -0800

Scientists Repurpose Adult Cells - "Scientists have transformed one type of fully developed adult cell directly into another inside a living animal, a startling advance that could lead to cures for a variety of illnesses and sidestep the political and ethical quagmires associated with embryonic stem cell research." [nature abstract, nature writeup, audio announcement]

Genetic discrimination

homunculus — Mon, 20 Aug 2007 14:10:54 -0800

U.S. military practices genetic discrimination in denying benefits. "Those medically discharged with genetic diseases are left without disability or retirement benefits. Some are fighting back."

Science

semmi — Wed, 13 Oct 2004 08:55:20 -0800

In terms of our genes, we humans are all the same -- except for the ways in which we're different. Pharmacogenomics has for years been touted as the ultimate benefit of the genomics revolution. But to many, this revolution has a troubling side.

father of the year

stupidsexyFlanders — Tue, 26 Aug 2003 06:51:23 -0800

Two of his children dying from a rare genetic disorder, Dad -- with no science background whatever -- starts a biotech company for the sole purpose of developing a drug that will cure them. Heartrending conflicts ensue. "Many times, I'd be talking aloud about programs and budgets, and at the back of my mind be thinking, 'Oh my God, this is not good for Megan and Patrick.' "

Trans Ova Genetics: Pharming Cows

hobbes — Mon, 25 Aug 2003 10:05:17 -0800

In lieu of today's posts on GM foods and meat, Trans Ova Genetics is pharming cows in hopes of creating one capable of adminstering human antibodies.

fvw — Mon, 10 Jun 2002 17:45:26 -0800

Are heart disease, cancer and schizophrenia caused by pathogens? The logic basically goes that a genetic disease cannot have a very high rate of occurrence as natural selection would prevent that gene from surviving (leaving the few occurrences of the disease that are caused by random mutation). Also: how to make diseases more benign by altering the parameters to their natural selection.