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Can We Influence Outcomes Together? How can people and computers be connected so that—collectively—they act more intelligently than any individuals, groups or computers have ever done before? Can collective intelligence save the planet? An MIT Sloan Management Review studies The Collective Intelligence Genome [pdf].
posted by netbros on May 5, 2011 - 4 comments

The New Biology - Eric Schadt's quest to upend molecular biology and open source it. (via)
posted by kliuless on Apr 9, 2011 - 35 comments

Invasive amniocentesis and chorionic villi sampling (CVS) tests are commonly used to determine the chromosomal, structural and genetic abnormalities in fetuses. But could they eventually become obsolete? A Chinese study has found that a complete copy of the fetal genome exists in the mother's blood, suggesting many prenatal diagnoses could potentially be performed noninvasively. [more inside]
posted by zarq on Dec 8, 2010 - 30 comments

There is no question that HIV is an ugly virus in terms of human health. Each year, it infects some 2.7 million additional people and leads to some two million deaths from AIDS. But a new album manages to locate some sonic beauty deep in its genome. Sounds of HIV (Azica Records) by composer Alexandra Pajak explores the patterns of the virus's nucleotides as well as the amino acids transcribed by HIV, playing through these biologic signatures in 17 tracks. [more inside]
posted by infinite intimation on Nov 12, 2010 - 20 comments

"The ability to design and create new forms of life marks a turning-point in the history of our species and our planet." - Freeman Dyson, on the J.C. Venter Institute's creation of a cell controlled by a synthetic genome. We are now in the business of engineering life.
posted by BoatMeme on May 20, 2010 - 62 comments

Neandertals are the closest ancestral relatives to modern humans. Today, Nature published a special report on the Neandertal genome, for which a draft sequencing of three billion nucleotides has been completed. This high-throughput sequencing project shows how the genetic relationship between Neandertals and modern Europeans and Asians suggests localized interbreeding between the two species roughly 40-80,000 years ago, complicating the common "out-of-Africa" story of how modern humans originated. Additional research extends this low-coverage, first-pass sequencing with a microarray approach that uncovers specific differences between the human and Neandertal genomes.
posted by Blazecock Pileon on May 6, 2010 - 75 comments

Followup to this post: A US District Court has ruled that Myriad Genetic's patents on breast cancer genes BRCA1 and BRCA2, which allow them to hold exclusive rights to a widely used genetic test for inherited breast and ovarian cancer susceptibility, are invalid. Genomics Law Report analyzes the ruling in two posts. The decision is likely to be challenged in a legal appeal — but if upheld, it could have huge implications for the biotechnology industry. [more inside]
posted by zarq on Mar 31, 2010 - 51 comments

We may soon be able to clone Neanderthals. But should we? An essay from Archaeology Magazine examines the ethical, scientific and legal ramifications. (Via Heather Pringle's Time Machine blog, where essay author Zach Zorich posted a reply and elicited a response.) [more inside]
posted by zarq on Feb 22, 2010 - 207 comments

The human population of Earth has almost always been about 50,000. [more inside]
posted by grobstein on Jan 19, 2010 - 85 comments

On behalf of medical organizations, universities, & individual patients, pathologists and genetics researchers, the ACLU has filed a lawsuit against Utah-based Myriad Genetics and the US Patent and Trademark Office. Myriad holds the US patents to the BRCA1 and BRCA2 genes, associated with hereditary causes of breast and ovarian cancers. Their patents guarantee the company the right to prevent anyone else from testing or studying those genes, which the ACLU says is unconstitutional and inhibits researchers from finding treatments and cures. [more inside]
posted by zarq on May 13, 2009 - 64 comments

We get you real woolly mammoth, very cheap, good quality.
posted by Brandon Blatcher on Nov 20, 2008 - 44 comments

Volunteers from the general public working together with researchers to advance personal genomics. 10 volunteers, among them noted author and cognitive psychologist Stephen Pinker, have open sourced (so to speak) their genetic information. [more inside]
posted by thatbrunette on Oct 20, 2008 - 13 comments

The Genius of Charles Darwin [more inside]
posted by chuckdarwin on Aug 8, 2008 - 66 comments

It turns out if it looks like a duck it's partly a duck. A bunch of scientist got together and set about to decode the platypus genome, and guess what!?! "What we found was the genome, just like the animal, is an amazing amalgam of reptilian and mammal characteristics with quite a few unique platypus characteristics as well". “You have got these reptilian repeat patterns and these more recently evolved milk genes and independent evolution of the venom. It all points to how idiosyncratic evolution is.” “We have microRNAs that are shared with chickens and not mammals as well as ones that are shared with mammals, but not chickens.” Also, apparently, male platypi have venomous spikes on their heels that can kill dogs! [more inside]
posted by Large Marge on May 8, 2008 - 46 comments

Scientists have built the first synthetic genome by stringing together 147 pages of letters representing the building blocks of DNA.
posted by geeknik on Jan 26, 2008 - 18 comments

The Diploid Genome Sequence of J. Craig Venter. (Previous MeFi)
posted by i_am_a_Jedi on Sep 16, 2007 - 31 comments

How to Sequence a Genome [Flash. H/T to Jay]. Visualization of the process of genetic sequencing. Posted on the Nova website in conjunction with their show, Cracking the Code of Life, hosted by Robert Krulwich [Wiki].
posted by McLir on Aug 23, 2007 - 14 comments

"Circos is designed for visualizing alignments, conservation and intra- and inter-chromosomal relationships within a genome, between genomes, or between any two or more sets of objects with a corresponding distance scale." Illustrative (via).
posted by stopgap on Jan 23, 2007 - 2 comments

A more efficient microbe genome. A more efficient sorting algorithm. A more efficient keyboard layout.
posted by fatllama on Aug 26, 2005 - 8 comments

Six degrees of Nirvana, see how bands are connected to each other.
posted by drezdn on Mar 16, 2005 - 46 comments

New Scientist reports that a virus has been built up from mail order components. Other reports on this are in USA Today and Nature. This isn't time life has been created in the lab, as previously linked.
What's interesting is that this study was funded by the Department of Energy to produce a completely man made lifeform that can create hydrogen or consume greenhouse gasses. The present virus is an artificially created copy of a naturally occurring virus.
posted by substrate on Nov 14, 2003 - 7 comments

"We are becoming the masters of our own DNA. But does that give us the right to decide that my children should never have been born?" John Sundman is a science fiction novelist and the father of two children with severe medical conditions. In this two-part article he shares his experiences and thoughts on bioethics, the Human Genome Project and whether genetics research is paving the way for a resurgent eugenics movement.
posted by homunculus on Oct 24, 2003 - 56 comments

DNA used to ascertain race of unidentified serial killer. Florida company DNAPrint Genomics claims their test can identify the race (ie, African, Caucasian, East Asian or American Indian) of a person from their DNA. CEO Tony Frudakis says that "of over 2,200 blind samples tested, the test is yet to get one wrong."
posted by shoos on Jun 5, 2003 - 12 comments

Dr Venter says he will be able to provide an individual's genome on a CD in about a week for $712,000 (£400,000) from later this year with the ultimate goal to sequence someone's entire genome in 24 hours for $1,000 (£562).
posted by nasim on Sep 23, 2002 - 9 comments

Genome liberation. "Life science researchers -- even those who work in academic settings -- are finding that corporations are just as eager to patent the tools as they are the data, and in many cases, universities are bending over backward to let the private sector have its way. As a result, a growing number of bioinformatics researchers are beginning to look to the free-software and open-source software movements for inspiration in their quest for bio freedom."
posted by homunculus on Feb 26, 2002 - 2 comments

Why Genetic Engineering Is So Dangerous Environmentalist/biologist Barry Commoner's essay in the February issue of Harper's magazine warns about the unknown dangers of genetic engineering. "...billions of transgenic plants are now being grown with only the most rudimentary knowledge about the resulting changes in their composition. Without detailed, ongoing analyses of the transgenic crops, there is no way of knowing what hazardous consequences may arise. But, given the failure of the Central Dogma, there is no assurance that they will not. The genetically engineered crops now being grown represent a huge uncontrolled experiment; its outcome is inherently unpredictable. Our project is designed to help develop effective public understanding of the dangerous implications of this critical predicament." He asserts that the "Central Dogma", the basis for the Human Genome Project, was known to be flawed prior to the inception of the $3 billion program. Should we be amused/impressed or very worried when we read about pig/spinach crosses and the like? Related article here.
posted by martk on Jan 25, 2002 - 16 comments

Last week I was watching a Nova program on PBS called 'Cracking the Code of Life', which brought to my attention a disturbing fact about the process of mapping the Human Genome; private companies have applied for patents for gene sequences that they've mapped. Many of these patents were applied for before the government began the Human Genome Project. Although the patent office has put these applications on hold until it figures out what to do with them, many drug companies an researchers won't work with a gene sequence if there is a patent application outstanding. You can get involved yourself by petitioning against patents on life.
posted by Sal Amander on May 1, 2001 - 22 comments

"There are only a few hundred genes that we have in the human genome that are not in the mouse genome," says Craig Venter, chief scientific officer at Celera Genomics. Information on the human genome released today reveals that there are far fewer genes than first thought - humans only have double the amount that worms and flies do. [more inside...]
posted by hijinx on Feb 11, 2001 - 6 comments

The Human Genome in Human Context: or How I Learned to Stop Worrying and Love the Genome.
posted by tallman on Dec 27, 2000 - 0 comments

The Missyplicity Project seeks to clone a dog for the first time in history - a specific dog named Missy. Missy is a beloved pet, getting on in years, whose wealthy owners wish to reproduce her. See also Genetic Savings and Clone
posted by riley370 on Dec 16, 2000 - 1 comment

Soon you can get your own copy of the Human Genome. (Funny, I thought I already had one.)
posted by Steven Den Beste on Sep 19, 2000 - 1 comment

A beta version of the source code for humans is now available for download.

Not that I'd have any idea what to do with this. Anyone up for a 740mb download?
posted by CrayDrygu on Jul 8, 2000 - 15 comments

!!!!!!!!!!!!!!!! Human Genome Project completed!!!!!
posted by grumblebee on Jun 25, 2000 - 7 comments

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