MetaFilter posts tagged with gfp

God schmod. I want my monkey man.

cjorgensen — Fri, 24 Oct 2008 07:37:06 -0800

"We'll breed him and we'll see if his kids glow, too!" Meet Mr. Green Genes: (No, not that Mr. Green Jeans) Pic. Pic. The Best Week Ever doesn't get it. This cat isn't Zappa's daddy either. previously. previously. previously.

Nobel Prize Chemistry 2008: The notorious GFP

NikitaNikita — Thu, 09 Oct 2008 09:38:35 -0800

The 2008 Nobel Prize in Chemistry was awarded to scientists who advanced the use of jellyfish green florescent protein, or GFP (previously), an indispensable tool in molecular biology. The man who discovered the GFP gene, however, is doing something quite different these days. More links: Several GFP derivatives of many different colors have been made, although I personally wouldn't encourage kids make bacteria/agar plate art, though. (more ">here, and Tsien's wreath for a department holiday party here. Such proteins not only allow the tagging of specific proteins, but also allow real-time imaging (read: movies!) of proteins moving about a cell in response to a stimulus. Martin Zimmer's page on GFP with more info, and a link to this, uhhh... [opinion withheld] "Notorious GFP" video. Profile pages on the winners: Roger Tsien, Martin Chalfie, and Osamu Shimomura.

OMG ... RFP Kitty!

scblackman — Wed, 12 Dec 2007 17:51:30 -0800

It all started in 1994 with GFP (green fluorescent protein) labeled E. coli and C. elegans (roundworm) cells. Once people realized that you could express the gene for a jellyfish protein in other cells without any other jellyfish-specific factors, it was possible to label any cell green simply by inserting the gene. Biologists realized the endless possiblities soon enough. GFP zebrafish (1997) [.pdf]. GFP mice (1998). GFP Bunny (more art than science, and previously ...) (2000). GFP monkey (2000). Fluorescent green pigs (2006). But nothing combines cuteness and transgentic more than the newly announced RFP (red fluorescent protein) kitty! And not only are they red fluorescent, but they're cloned to boot!

Somewhere, over the brainbow...

kisch mokusch — Thu, 01 Nov 2007 03:09:26 -0800

Brainbow. Using some very cool genetic tricks, Harvard scientists have found a way to make transgenic mice that express various mixtures of different coloured fluorescent proteins in their neurons. The result, individual brain cells with up to 90 distinct colours. Not surprisingly, this visually impressive work is in this month's issue of Nature.