The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
Doing his best Orson Welles impression, Ze Frank administers a Voight-Kampff Test to a Vancouver TED audience.
Norbert Wiener: The Eccentric Genius Whose Time May Have Finally Come (Again) - "The most direct reason for Wiener's fall to relative obscurity was the breakthrough of a young mathematician and engineer named Claude Shannon." [more inside]
The Two Cultures and the Scientific Revolution - "[Charles Percy Snow] was pleading for a more adequately educated ruling class so that the suffering of the poor might be ameliorated... Snow wanted to believe something like this: political decisions in the modern world often concern how to deploy science and technology, so people well-trained in science and technology will be better prepared to make those decisions. But that's a syllogism without a minor premise." (previously) [more inside]
Is Psychometric g a Myth? - "As an online discussion about IQ or general intelligence grows longer, the probability of someone linking to statistician Cosma Shalizi's essay g, a Statistical Myth approaches 1. Usually the link is accompanied by an assertion to the effect that Shalizi offers a definitive refutation of the concept of general mental ability, or psychometric g." [more inside]
Professors' global model forecasts civil unrest against governments - With protests spreading in the Middle East (now Yemen - not on the list) I thought this article and blog on a forecast model predicting "which countries will likely experience an escalation in domestic political violence [within the next five years]" was rather interesting. [more inside]
Shared social responsibility - When customers could pay what they wanted in the knowledge that half of that would go to charity, sales and profits went through the roof ... Gneezy describes the combination of charitable donations and paying what you like as 'shared social responsibility', where businesses and customers work together for the public good. (via mr) [also see 1,2,3]
The experimental method: Testing solutions with randomized trials -- In trying to help explicate the complexity of society Clark Medal-winner Esther Duflo is raising the productivity of social policies by increasing our knowledge of what works and doesn't work through repeated social experiments of randomised controlled trials. She has a large surplus labour pool, a veritable industrial reserve army, to worth with. [more inside]
Clean water is a right: "The United Nations Development Programme (UNDP) published its annual report on human development. It denounces the world's complacent disregard for such unglamorous subjects as standpipes, latrines and the 1.8m children who die each year from diarrhoea because the authorities cannot keep their drinking water separate from their faeces. The study is both coldly analytical and angry..."