2 years ago I FPP'd FlavorPill, a company that sends out permission-based emails for books (Boldtype), music (Earplug), and fashion (the JC Report). They've since added ArtKrush (it's art, stupid! - nsfw) and Activate (world events) to their aresenal. In addition to the topic-specific mailing lists, they offer city-specific lists for London, New York, SF, LA, and Chicago. Sample issues are archived on the site.
Nannybots and mailing lists don't mix - especially nannybots that have gone insane!