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Vulnerable to coercion or undue influence

A two-part series on problems in the clinical trials industry, from Medium.com:
The Best-Selling, Billion-Dollar Pills Tested on Homeless People
How the destitute and the mentally ill are being used as human lab rats
and
Why Are Dope-Addicted, Disgraced Doctors Running Our Drug Trials?
posted by Joe in Australia on Aug 5, 2014 - 28 comments

Iron square = :| but Iron fish = (ツ)

The Good-Luck Charm That Solved a Public-Health Problem ¸.·´¯`·.´¯`·.¸¸.·´¯`·.¸><(((º> [more inside]
posted by joseph conrad is fully awesome on Aug 3, 2014 - 44 comments

The End of Unrestricted Celebrity Medicine?

A policy before the Medical Society of the State of New York to regulate celebrity medical expertise
posted by Renoroc on Jul 14, 2014 - 37 comments

"in the United States, how it spread, who got it, and why"

Why Did AIDS Ravage the U.S. More Than Any Other Developed Country?
Solving an epidemiological mystery
posted by davidstandaford on May 18, 2014 - 77 comments

Bounty Mutiny

"If an NHS trust proposed today that it was going to introduce Viagra sales reps into men's genitourinary wards, or reps for walking aids to orthopaedic wards, the very least you'd expect would be some stout resistance. It is a measure of the strength of the association between "motherhood" and "buying stuff" that the presence of commercial representatives on maternity wards has been tolerated for so long."
[more inside]
posted by Catseye on Apr 23, 2014 - 29 comments

Is the Contraceptive NuvaRing Killing Thousands?

"Danger in the Ring." According to Karen, a doctor in the emergency room asked her over the phone: “Was your daughter using birth control?” Karen said, “Yes, NuvaRing.” He removed the device and said, “I thought so, because she’s having a pulmonary embolism.” [more inside]
posted by blue suede stockings on Dec 28, 2013 - 103 comments

The 'grotesque beauty' of medieval Britons' diseased bones

Digitised Diseases is an open access resource featuring human bones which have been digitised using 3D laser scanning, CT and radiography. The resource focuses on a wide range of pathological type specimens from archaeological and historical medical collections, specifically examples of chronic diseases which affect the human skeleton for which many of the physical changes are often not directly observable within clinical practice. Of major interest to many will be high fidelity photo-realistic digital representations of 3D bones that can be viewed, downloaded and manipulated on their computer, tablet or smartphone. [more inside]
posted by shoesfullofdust on Dec 9, 2013 - 7 comments

"...research that is scientifically valuable but morally disturbing."

The Nazi Anatomists. "How the corpses of Hitler's victims are still haunting modern science—and American abortion politics."
posted by zarq on Nov 6, 2013 - 28 comments

The Pills of Last Resort

How Dying Patients Get Access to Experimental Drugs
posted by Blazecock Pileon on Nov 1, 2013 - 16 comments

'You need to say, 'I'm Devin Wang and I'm the person in that picture."

Portrait of a Rescue (marathon bombing photos) [more inside]
posted by roomthreeseventeen on Oct 31, 2013 - 14 comments

'Paying Till It Hurts': Why American Health Care Is So Pricey

NPR's Fresh Air interviews Elizabeth Rosenthal about her year spent investigating the high cost of health care.
"Every part of the system needs to rethink the way it's working. Or maybe what I'm really saying is we need a system instead of 20, 40 components, each one having its own financial model, and each one making a profit." [more inside]
posted by arcticseal on Aug 11, 2013 - 105 comments

A Marital Tour of Misguided Medicine

Dr. Sydnee McElroy and her husband Justin welcome you to Sawbones: A Marital Tour of Misguided Medicine. Every Friday, they dig through the annals of medical history to uncover all the odd, weird, wrong, dumb and just gross ways we've tried to fix people over the years. [more inside]
posted by pjern on Aug 10, 2013 - 8 comments

Beyond recognition: the story of Carmen Tarleton's face transplant

"The first time I went into the grocery store, nobody looked at me. And I noticed [that] nobody looked at me. And that, well that's sort of really nice." In 2007, Carmen Tarleton was assaulted by her ex-husband, resulting in chemical burns over 80% of her body. She recovered after dozens of surgeries, but her face was severely disfigured. In February 2013, Cheryl Denelli-Righter suffered a stroke that left her brain-dead. Her daughter Marinda was approached to see if she was willing to donate her mother's face. This past Valentine's day, Carmen received her face transplant, the 29th in the world. This is their story. (note: article contains photos and video of Carmen both before and after the transplant.) [more inside]
posted by Homeboy Trouble on Jun 5, 2013 - 27 comments

On Medical Neutrality

In 2011, the CIA reportedly hired a doctor in Pakistan to conduct espionage while giving vaccinations to children. In response, Pakistan expelled Save the Children from the country. The New England Journal of Medicine comments on military operations masquerading as humanitarian relief. [more inside]
posted by painquale on May 21, 2013 - 41 comments

She could put her lips together for the first time. “It was beautiful."

Groundbreaking Surgery for Girl Born Without Windpipe: [New York Times] — Using plastic fibers and human cells, doctors have built and implanted a windpipe in a 2 ½-year-old girl — the youngest person ever to receive a bioengineered organ.
posted by Fizz on Apr 30, 2013 - 16 comments

As a potential role model, I advocate it.

Then Christine stumbled upon a controversial homemade herbal remedy that she credits with enormously improving her dog's quality of life. She's grateful that, in his final year, Sampson weighed in at a robust 106 pounds and lived free of the wracking pain that had haunted him. Whereas before Sampson had been too weak to walk, almost overnight he became a born-again youngster. "He was a puppy again, happy and playful," Christine recalls. "He'd trot around the house with his toys in his mouth, wanting to play fetch!" Legalize medical marijuana for dogs! (Don't miss the great picture of Mason the Vizsla looking very relaxed!) [more inside]
posted by grobstein on Feb 27, 2013 - 50 comments

That is easily enough to fracture multiple facial bones, and is probably going to knock you out cold.

So, how badly injured were the burglars in Home Alone, really?
posted by The Whelk on Dec 20, 2012 - 48 comments

H+

This past August, producer Bryan Singer (The Usual Suspects, X-Men) launched a new digital series: H+. The premise: in the near future, 33% of humanity has retired their smartphones, tablets and computers in favor of an implanted computer system, H+, which connects them directly to the internet 24/7. The story begins as a computer virus attacks the implants, killing billions. In intersecting storylines across four continents (told in part through flashbacks,) the series then unravels what happened, who caused it and why. [more inside]
posted by zarq on Dec 19, 2012 - 66 comments

.

On November 30, the Tampa Bay Times published a sympathetic profile of Spring Hill, FL resident Gretchen Molannen: "Persistent genital arousal disorder brings woman agony, not ecstasy." Her condition, also known as PGAD, is a rare sexual disorder (not recognized by the DSM,) 'characterized by spontaneous, persistent, unwanted sexual arousal unrelated to feelings of sexual desire.' The Times reported that Ms. Molannen's condition had virtually destroyed her personal and professional life and led to several suicide attempts. One day after the article was published, she successfully committed suicide. [more inside]
posted by zarq on Dec 7, 2012 - 40 comments

"Cocaine for Snowblindness"

You're about to be the base doctor at Halley Research Station in Antarctica for a year. For ten months, no one gets in or out. Fourteen lives are in your hands, including your own. What do you put in your medical kit? And how do your choices differ from those of your predecessors (Eric Marshall and Edward Wilson) a century ago?
posted by zarq on Oct 2, 2012 - 8 comments

The Gateway Drug to Twinkie Addiction.

Question 3 is a Massachusetts ballot initiative concerning the legalization of marijuana for medical use. There are some organizations opposed to the initiative, who failed to register certain domain names. The Massachusetts voter's guide accidentally directed voters to one of the unclaimed domains, now the satirical VoteNoOnQuestion3.org
posted by Devils Rancher on Sep 16, 2012 - 44 comments

"The FDA recalled more than 60,000 tissue-derived products between 1994 and mid-2007."

"The business of recycling dead humans into medical implants is a little-known yet lucrative trade. But its practices have roused concerns about how tissues are obtained and how well grieving families and transplant patients are informed about the realities and the risks." After an eight month international investigation, the International Consortium of Investigative Journalists has published an extensive four-part exposé into the black market for cadavers and human tissue: Skin and Bone: The Shadowy Trade in Human Body Parts (Via) [more inside]
posted by zarq on Jul 20, 2012 - 32 comments

In the Public Interest....

Earlier this year, six scientists and doctors filed a lawsuit against the US Food and Drug Administration alleging that the FDA had secretly monitored their personal e-mail accounts after they (legally) warned Congress that the "agency was approving medical devices that they believed posed unacceptable risks to patients." The agency said it had done so to "investigate allegations that the employees had leaked confidential information to the public." At the time, the FDA indicated their computer monitoring was limited to five scientists. But now, the New York Times is reporting that "what began as a narrow investigation" "quickly grew in mid-2010 into a much broader campaign to counter outside critics of the agency’s medical review process.". [more inside]
posted by zarq on Jul 15, 2012 - 29 comments

Hunting down my son's killer

Matt Might, computer science professor, has a son with a new genetic condition. This is the story of how they figured this out. Matt Might, perhaps best known for the illustrated guide to a PhD, tells the wrenching tale of their son's terrible medical condition and how they've worked to figure out what is going on with him.
posted by k8t on May 29, 2012 - 38 comments

The Avian Flu: Transparency vs. Public Safety

"Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets." After an extensive, months-long debate, one of two controversial papers showing ways the H5N1 "avian" influenza virus could potentially become transmissible in mammals with only 3 or 4 mutations was published in Nature today. The journal included an editorial on the merits and drawbacks of "publishing risky research" with regard to biosafety. The debate included an unprecedented recommendation by The US National Science Advisory Board for Biosecurity (NSABB) to block publication -- a decision they later reversed. (Via: 1, 2) Nature's special report has additional articles, including interviews with the teams behind both papers.
posted by zarq on May 3, 2012 - 37 comments

"If you have your checkbook in your car I will be happy to wait for you."

Hospitals in Minnesota have hired a collections company that plants its employees in the ER, squeezing money out of patients before they can get further care.
posted by reenum on Apr 24, 2012 - 67 comments

To read or not to read

How to read a paper is a series by Trisha Greenhalgh in BMJ, the British Medical Journal, that explains how to critically read and apply the biomedical literature. Deciding what the paper is about. Assessing methodological quality. Statistics for the non-statistician: parts I and II. Drug trials, diagnostic and screening tests, economic analyses, systematic reviews and meta-analyses (PDF), and qualitative research (PDF).
posted by grouse on Apr 19, 2012 - 14 comments

An old timer's first time medical marijuana experience

A retired grandfather receives his medical marijuana card. He's never smoked before, and is trying it because he feels he is taking too many pills to control his back pain, anxiety, rage, and more. His exploration of the logistics (especially the pipe lighting techniques) is really quite charming.
posted by punocchio on Feb 16, 2012 - 49 comments

Insurance. The numbers just. Don't. Work.

Kevin Zelnio is a science writer with a degree in marine biology. He is the father of two children. And, like many in this country, he has no insurance. Earlier this week, his 6 year-old developed pneumonia.This is his account of what happened.
posted by Laminda on Feb 11, 2012 - 201 comments

They were lab rats, just like Tuskeegee

In the 1940s, US doctors deliberately infected thousands of Guatemalans with venereal diseases. The wound is still raw.
posted by mattbucher on Feb 10, 2012 - 22 comments

"I'm a cybernetic organism. Living tissue over a metal endoskeleton."

Woman, 83, Has World’s First Lower Jaw Replacement – In 3D [abc.com] In what has been called the first operation of its kind, an 83-year-old woman in the Netherlands has been fitted with a custom-made artificial jaw that was created by a 3D printer. The titanium implant, which weighs less than 4 ounces, was created by taking a CT scan of the woman’s lower jaw and duplicating it with a 3D printer that lays down titanium powder instead of ink. The printer followed the pattern of the woman’s jaw bone layer by layer, fusing the titanium powder in place with heat. In just a couple hours, the 3D replica was ready.
posted by Fizz on Feb 7, 2012 - 43 comments

A nation full of immortal poor people.

In 2002, Doug Monroe placed his parents in assisted living. A decade later, he's looking back at "the weighty financial and emotional costs that come with a parent's immortality": The Long Goodbye.
posted by zarq on Jan 25, 2012 - 85 comments

Animating Medicine

Bioanimation companies like XVIVO, Hybrid Medical (Previously), Random42, Biolucid, Argosy Medical, and BioDigital have been doing beautiful work for hire, freely available to watch. [more inside]
posted by Blasdelb on Jan 23, 2012 - 10 comments

Data Driven to Distraction

As Doctors Use More Devices, Potential for Distraction Grows — Do too many digital devices distract doctors from their daily rounds and endanger patients?
posted by cenoxo on Dec 17, 2011 - 24 comments

Never Events

The term never event describes when something happens in a medical setting that should never occur. The list of never events (formally called "Serious Reportable Events) released by the NQF includes mistakes such as performing surgery on the wrong body part (or the wrong patient!), or patient suicide while under care. Despite their moniker, "never" events do happen. [more inside]
posted by Deathalicious on Nov 28, 2011 - 53 comments

Don't get hysterical

Indian man has hysterectomy after doctors find uterus. The 35 year-old farmer and father of two had a full female reproductive system, which was removed from his stomach at a Chhindwara district hospital. Joan Rivers is probably not surprised.
posted by Laminda on Aug 3, 2011 - 29 comments

Does it really make you fat?

Health News Review rates and reviews medical reporting in US media. [more inside]
posted by nangar on Jul 16, 2011 - 1 comment

"There are no national standards or regulations regarding forensic pathology and practices vary widely from place to place."

The Hardest Cases: When Children Die, Justice Can Be Elusive A joint investigation by PBS Frontline, ProPublica and NPR has found that medical examiners and coroners have repeatedly mishandled cases of infant and child deaths, helping to put innocent people behind bars. (Via. (Article contains descriptions of children that have been killed by abuse. May be disturbing / triggering to some readers.) [more inside]
posted by zarq on Jun 28, 2011 - 20 comments

"Let's stop harvesting brains."

The Spam Factory's Dirty Secret. Undocumented workers, an autoimmune mystery traced to aerosolized pork brains from increased line production speed, and what sounds like one of the worst jobs in America.
posted by availablelight on Jun 27, 2011 - 46 comments

Not only can't you get an abortion, but no one knows how to perform one, anyway.

On Wednesday, the House approved an amendment from Rep. Virginia Foxx (R-N.C.) that would prevent a federal healthcare education fund from being used for abortion or to provide for training for abortion procedures. [more inside]
posted by anya32 on May 27, 2011 - 54 comments

What It's Like To Get A Breast Reduction

A young woman writes about her breast reduction.
posted by reenum on May 18, 2011 - 99 comments

No Mo-99

A Political Meltdown: For decades, Canada has been a world leader in the production of medical isotopes. So why did the government announce that it was dumping the entire program? (alt)
posted by Orange Pamplemousse on Apr 9, 2011 - 22 comments

The Ship Captain’s Medical Guide

The Ship Captain’s Medical Guide. The Ship Captain’s Medical Guide is intended primarily for use on ships where no doctor is carried and it is necessary for laymen to assess and treat injuries and to diagnose and treat ill health. The Guide can also be recommended for use in other situations where professional medical advice is not readily available, for example on expeditions.
posted by leigh1 on Apr 7, 2011 - 35 comments

Hidrodentitis and Halitosis and Hilarious

Embarassing Bodies, your one-stop clinical revulsion shop! Is it painful? And does it ooze? Pus and blood? Yep, that sounds nasty. [warning: NASTY] [more inside]
posted by Ambrosia Voyeur on Apr 1, 2011 - 23 comments

family planning, old school

Antique contraception & protection from the disease - (NSFW) male & female methodologies of birth control from antiquity to the 1900s in pictures and text (Translated from Russian) [more inside]
posted by madamjujujive on Mar 12, 2011 - 19 comments

Two Thumbs Up

Roger Ebert gets a new chin An inspirational story; and he is due back on TV real soon.
posted by Jaymzifer on Jan 20, 2011 - 47 comments

A Not-So-Brief History of Pitching Injuries, Starring Nolan Ryan and the Texas Rangers

Jonah Keri looks at the unconventional methods being used by the Texas Rangers to improve the durability and effectiveness of their pitching staff.
posted by reenum on Dec 20, 2010 - 13 comments

The Beautiful Mind

"It is only fitting that the story of the brain should be a visual one, for the visuals had the ancients fooled for millenniums. The brain was so ugly that they assumed the mind must lie elsewhere. Now those same skeletal silhouettes glow plump and brightly colored, courtesy of a variety of inserted genes encoding fluorescent molecules. A glossy new art book, “Portraits of the Mind,” hopes to draw the general reader into neuroscience with the sheer beauty of its images." Slide Shows: The Beautiful Mind and Portraits of the Mind [more inside]
posted by zarq on Dec 2, 2010 - 6 comments

Pharmacologic Waterboarding

The Defense Department forced all "war on terror" detainees at the Guantanamo Bay prison to take a high dosage of a controversial antimalarial drug, mefloquine, an act that an Army public health physician called "pharmacologic waterboarding". The US military administered the drug despite Pentagon knowledge that mefloquine caused severe neuropsychiatric side effects, including suicidal thoughts, hallucinations and anxiety. The drug was used on the prisoners whether they had malaria or not. [more inside]
posted by Joe Beese on Dec 2, 2010 - 73 comments

The man with no face gets a face

Twelve pound tumor removed from man's face. Previously, the original situation on MetaFilter.
posted by antgly on Nov 7, 2010 - 22 comments

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