On November 30, the Tampa Bay Times published a sympathetic profile of Spring Hill, FL resident Gretchen Molannen: "Persistent genital arousal disorder brings woman agony, not ecstasy
." Her condition, also known as PGAD, is a rare sexual disorder (not recognized by the DSM,) 'characterized
by spontaneous, persistent, unwanted sexual arousal unrelated to feelings of sexual desire.' The Times reported that Ms. Molannen's condition had virtually destroyed her personal and professional life and led to several suicide attempts. One day after the article was published, she successfully committed suicide
. [more inside]
posted by zarq
on Dec 7, 2012 -
Can’t get enough of these videos from AsapSCIENCE. Here’s an earlier one from the Your Brain On Drugs series entitled marijuana. I was pretty stoned when watching it and ended up cracking up at the funny cats – total highlight for me. Can’t remember the gist, but you should definitely check it out.
posted by infini
on Nov 23, 2012 -
But back in 1996, users of the proto-Web community Usenet got spammed with messages that reached an almost transcendent level of bizarre—a weirdness so precise it implied the influence of a very human intelligence. “Markovian Parallax Denigrate,” read the title of each post, followed by a mountain of seemingly meaningless word spew:
Unraveling the Internet’s oldest and weirdest mystery
posted by the man of twists and turns
on Nov 20, 2012 -
Nanoparticles covered in proteins trick immune system.
A breakthrough new experimental treatment that uses nanoparticles covered with proteins to trick the immune system, managed to stop it attacking myelin and halt disease progression in mice with relapsing remitting multiple sclerosis (MS). The researchers say the approach may also be applicable to other auto-immune diseases such as asthma and type 1 diabetes.
posted by aleph
on Nov 19, 2012 -
"Why do parasites harm their hosts? Conventional wisdom holds that because parasites depend on their hosts for survival and transmission, they should evolve to become benign, yet many parasites cause harm. Theory predicts that parasites could evolve virulence (i.e., parasite-induced reductions in host fitness) by balancing the transmission benefits of parasite replication with the costs of host death. This idea has led researchers to predict how human interventions—such as vaccines—may alter virulence evolution, yet empirical support is critically lacking." Two papers
demonstrate empirical evidence for related models predicting the origin of virulence: [more inside]
posted by Blasdelb
on Oct 21, 2012 -
Heaven is Real: A Doctor's Experience of the Afterlife. As a neurosurgeon, I did not believe in the phenomenon of near-death experiences...In the fall of 2008, however, after seven days in a coma during which the human part of my brain, the neocortex, was inactivated, I experienced something so profound that it gave me a scientific reason to believe in consciousness after death.
posted by shivohum
on Oct 12, 2012 -
The drugs don't work
: a modern medical scandal - "The doctors prescribing the drugs don't know they don't do what they're meant to. Nor do their patients. The manufacturers know full well, but they're not telling.
posted by Gyan
on Sep 22, 2012 -
First published in 1997, Anne Fadiman's book
The Spirit Catches You and You Fall Down, a chronicle of a Hmong refugee family's interactions
with the American medical system in the face of a child's devastating illness
, has become highly recommended, if not required, reading for many medical students and health care professionals, over the past 15 years quietly changing how young doctors approach patients
from different cultures. On August 31, with little publicity, Lia Lee, the young girl who inspired the book, after living most of her life in a persistent vegetative state, quietly died [NYT obit]
posted by Slarty Bartfast
on Sep 15, 2012 -
20% of Anorexics Are Men.
And that number is reportedly rising. "Diagnosis is hard. Finding treatment is even harder. Many residential centers don't admit men, out of a belief that treatment should be sex-specific." Article contains images and descriptions that may be disturbing to those with eating disorders. Single page version here.
posted by zarq
on Sep 13, 2012 -
The Medical School at the University of California, San Francisco “presents Mini Medical School
for the Public, a series of programs providing an opportunity to learn about health and the health sciences directly from UCSF faculty members and other nationally-recognized experts.”
Videos particularly geared toward integrative medicine and healthy living can be found here.
(Most of the videos are between sixty and ninety minutes long.) [more inside]
posted by ferdydurke
on Sep 8, 2012 -
Two-year-old Emma wanted to play with blocks, but a condition called arthrogryposis meant she couldn't move her arms. So researchers at a Delaware hospital 3D printed a durable custom exoskeleton with the tiny, lightweight parts she needed
posted by Foci for Analysis
on Aug 3, 2012 -
In less than an hour, the Supreme Court will hand down its final judgment in what has become one of the most crucial legal battles of our time: the constitutionality of President Obama's landmark health care reform law.
The product of a strict party line vote following a
of debate, disinformation
, and tense legislative wrangling, the Affordable Care Act
would (among other popular reforms
) require all Americans to buy insurance coverage by 2014, broadening the risk pool
for the benefit of those with pre-existing conditions.
The fate of this "individual mandate," bitterly opposed by Republicans despite its similarity to past plans touted by conservatives
(including presidential contender Mitt Romney
) is the central question facing the justices today
. If the conservative majority takes the dramatic step
of striking down the mandate, the law will be toothless, and in danger of wholesale reversal, rendering millions uninsured
, dealing a crippling blow to the president's re-election hopes, and possibly endangering the federal regulatory state
But despite the pessimism of bettors
, some believe
the Court will demur, wary of damaging
its already-fragile reputation
with another partisan 5-4 decision
. But those who know don't talk, and those who talk don't know
. Watch the SCOTUSblog liveblog
for updates, Q&A, and analysis as the truth finally comes out shortly after 10 a.m. EST.
posted by Rhaomi
on Jun 28, 2012 -
"Adrian Owen still gets animated when he talks about patient 23.
The patient was only 24 years old when his life was devastated by a car accident. Alive but unresponsive, he had been languishing in what neurologists refer to as a vegetative state for five years, when Owen, a neuro-scientist then at the University of Cambridge, UK, and his colleagues at the University of Liège in Belgium, put him into a functional magnetic resonance imaging (fMRI) machine and started asking him questions. Incredibly, he provided answers."
posted by jquinby
on Jun 15, 2012 -
Scientists investigate the use of psychedelic drugs in end of life therapy
"Grob and his colleagues are part of a resurgence of scientific interest in the healing power of psychedelics. Michael Mithoefer, for instance, has shown that MDMA is an effective treatment for severe P.T.S.D. Halpern has examined case studies of people with cluster headaches who took LSD and reported their symptoms greatly diminished. And psychedelics have been recently examined as treatment for alcoholism and other addictions. "
posted by bookman117
on May 18, 2012 -
The emergence of a citation cartel.
"Cell Transplantation is a medical journal published by the Cognizant Communication Corporation of Putnam Valley, New York. In recent years, its impact factor has been growing rapidly. In 2006, it was 3.482. In 2010, it had almost doubled to 6.204.
When you look at which journals cite Cell Transplantation, two journals stand out noticeably: the Medical Science Monitor, and The Scientific World Journal. According to the JCR, neither of these journals cited Cell Transplantation until 2010.
Then, in 2010, a review article was published in the Medical Science Monitor citing 490 articles, 445 of which were to papers published in Cell Transplantation. All 445 citations pointed to papers published in 2008 or 2009 — the citation window from which the journal’s 2010 impact factor was derived. Of the remaining 45 citations, 44 cited the Medical Science Monitor, again, to papers published in 2008 and 2009.
Three of the four authors of this paper sit on the editorial board of Cell Transplantation. Two are associate editors, one is the founding editor. The fourth is the CEO of a medical communications company."
(from Scholarly Kitchen
, via Andrew Gelman
posted by escabeche
on May 15, 2012 -
Bombshell investigation reveals vast majority of landmark cancer studies cannot be replicated.
In a shocking discovery, C. Glenn Begley, former researcher at Amgen Inc, and a team working with him, has found that 47 out of 53 so called "landmark" basic studies on cancer -- a high proportion of them from university labs -- cannot be replicated, with grim consequences for producing new medicines in the future. These were papers in top journals, from reputable labs, which achieved landmark status with frequent citations. The consequences for cancer research are far-reaching. [more inside]
posted by VikingSword
on Mar 30, 2012 -
A Cephalic Infusion
Take dry Peacocks dung (the white part) 4 ounces; Millepedes alive bruised 1 ounce; black Cherry water, white Wine, each 1 pint and half; let them stand cold 24 hours, then having clarify'd it, by often passing it through a Flannel bag; add Langius's Antepileptic water 3 ounces; Spirit of Lavender compound 1 dram and half; Oil of Nutmeg 3 drops; Syrup of Piony compound 6 ounces, mix.
It cleanses out the Meatus of the Brain, when choak'd up and grown unpassable, by reason of muddy Feculencies, roborates its Tone when flaccid and suck, and defecates the Animal Spirits, when clog'd and incens'd with an heterogeneous Copula, refreshes and invigorates them when feeble and fainting; discusses the Mists and Clouds of the Head, and procures Serenity and Sun shine. Therefore we employ it with happy Success in an Idiopathic Head-ach, Vertigo, Scotomy, &c. giving a quarter of a pint Nights and Mornings.
800 medicines from Thomas Fuller's Pharmacopeia Extemporanea
, 168 from William Buchan's Domestic Medicine
and 11 from The Reverend Twigge's Notebook - indexed and fully searchable
posted by unliteral
on Feb 22, 2012 -
In March 2010, a pair of health inspectors responding to multiple tips paid a three-day visit to the factory headquarters of the Poly Implant Prothese
(PIP) company, a leading international maker of breast implants. On their second day, the inspectors found something odd: six discarded plastic containers of Silopren, a liquid silicone designed for industrial, not medical use, lined up along the outside wall of the production site. The lead inspector estimated they had contained nearly 9 tons of liquid silicone. It now appears as if between 300,000 and 400,000 women throughout the world may have received potentially toxic, faulty breast implants containing ingredients never clinically tested on humans, manufactured and distributed by a company that knowingly deceived regulators, suppliers, distributors, medical professionals and ultimately, patients.
Reuters photographer's Blog: Operating on an implant scandal. (Last link NSFW, graphic images that contain nudity.) [more inside]
posted by zarq
on Feb 18, 2012 -
"I'm banned," he says. "By whom?" I ask. "My landlord," he says. "And the Swedish Radiation Safety Authority."
Jon Ronson on DIY science
posted by fearfulsymmetry
on Feb 4, 2012 -
"I would point out to you that medical explanations are modern. That Americans today want medical explanations for things that in the 19th century would have been explained by hysteria, and in the 18th century would have been explained by religious conversion experiences in the context of the Great Awakening, when people were having these types of fits, and in the 17th century by witchcraft."
posted by empath
on Jan 30, 2012 -
Day at Night
was an interview series on the public television station of the City University of New York that aired from 1973-4. CUNY TV is in the process of digitizing and uploading the 130 episodes that were produced, with 46 done so far. The episodes are just under half an hour in length. Among the people interviewed by host James Day are author Ray Bradbury
, actress Myrna Loy
, medical researcher Jonas Salk
, singer Cab Calloway
, writer Christopher Isherwood
, nuclear scientist Edward Teller
, comedian Victor Borge
, tennis player Billie Jean King
, linguist and activist Noam Chomsky
, composer Aaron Copland
, actor Vincent Price
and boxer Muhammad Ali
posted by Kattullus
on Jan 16, 2012 -