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Intergenerational mouse trauma

...Ressler... and Dias wafted the scent [of acetophenone] around a small chamber, while giving small electric shocks to male mice. The animals eventually learned to associate the scent with pain, shuddering in the presence of acetophenone even without a shock. Despite never having encountered acetophenone in their lives, the offspring exhibited increased sensitivity when introduced to its smell, shuddering more markedly in its presence compared with the descendants of mice that had been conditioned to be startled by a different smell or that had gone through no such conditioning.
posted by latkes on Jan 9, 2014 - 34 comments

Mouseland

Mouses Houses 'Pictures from my own private mouseland' (tumblr) [more inside]
posted by fearfulsymmetry on Dec 5, 2013 - 19 comments

Blessed are the cheesemakers

Bacteria from personalities has been used to make human cheese as part of an exhibition on synthetic biology in Dublin. This included cheeses grown from bacteria from various belly buttons, noses, armpits, tears, mouths and toes. If that's a bit too strong for you, then other exhibits in the show include humans reproducing dolphins for food, and mice cloned from Elvis Presley's DNA.
posted by Wordshore on Nov 20, 2013 - 40 comments

Mouseunculus

Mouseunculus: How The Brain Draws A Little You. [Via]
posted by homunculus on Jul 25, 2013 - 16 comments

Mouse cloned from drop of blood

Scientists in Japan have cloned a mouse from a single drop of blood. (via)
posted by kliuless on Jun 30, 2013 - 33 comments

Intelligence Tests

Is Psychometric g a Myth? - "As an online discussion about IQ or general intelligence grows longer, the probability of someone linking to statistician Cosma Shalizi's essay g, a Statistical Myth approaches 1. Usually the link is accompanied by an assertion to the effect that Shalizi offers a definitive refutation of the concept of general mental ability, or psychometric g." [more inside]
posted by kliuless on Apr 11, 2013 - 113 comments

Probiotics...better than valium?

Why the bacteria in food like yogurt may be the answer to anxiety and depression. Probiotic-rich food is good for your gut, but it may also be good for your brain, say researchers.
posted by cherrybounce on Mar 21, 2013 - 51 comments

New frontiers in invasive species containment

Scientists to drop dead mice laced with Tylenol on Guam from helicopters
posted by silby on Feb 23, 2013 - 51 comments

Badass Mouse is badass.

The little mouse that eats scorpions AND adorably howls at the moon.
posted by Kitteh on Jan 21, 2013 - 32 comments

Clever Critters

Trickmousing: mice doing tricks, being awesome. [more inside]
posted by quin on Dec 31, 2012 - 29 comments

Why a calorie is not a calorie

The known knowns, known unknowns, and perhaps even the unknown unknowns of why a calorie is not a calorie.
posted by NortonDC on Aug 27, 2012 - 96 comments

feed with soft paint brush when very young or fussing

How to care for a baby mouse.
posted by that's how you get ants on Jun 10, 2012 - 27 comments

Loving You, as the Mouse Loves the Rice

Mouse Loves Rice isn't really a well-known song in the English-speaking west, but it's been huge throughout east Asia since it first hit the net in 2004. The music video (here in English) covers all the big timeless truths about life: beauty, the nature of love, sacrifice, and human-mouse transformation. [more inside]
posted by barnacles on Apr 15, 2012 - 25 comments

John Calhoun's Mouse Utopia

How do you build a mouse Utopia? In 1972, John B. Calhoun detailed the specifications of his Mortality-Inhibiting Environment for Mice: a practical utopia built in the laboratory. . . . To its members, the mouse civilization of Universe 25 must have seemed prosperous indeed. But its downfall was already certain—not just stagnation, but total and inevitable destruction.
posted by saladin on Aug 18, 2011 - 27 comments

Excitingly trans-genic mice

"On the surface, it looks as if our identity as male or female is determined in the womb. The decision seems final – a genetic switch flicks towards either setting, and locks into place for the rest of our lives." [more inside]
posted by Blasdelb on Jul 24, 2011 - 54 comments

Serotonin, mice and a good time

Interesting effect on the lack of the neurotransmitter serotonin in male mice.
posted by Brandon Blatcher on Mar 23, 2011 - 37 comments

The Future Gets Closer, Part IV: Mouse Edition

Some scientists have used stem cells to regenerate myelin in mice, paving the way for new MS treatments. Other scientists have created mice from two fathers. Meanwhile, using stem cells to treat paralysis advances from mice to monkeys.
posted by StrikeTheViol on Dec 9, 2010 - 23 comments

USDA glues acetaminophen-laced frozen mice to cardboard, bombs Guam treetops to kill snakes

USDA glues acetaminophen-laced frozen mice to cardboard, bombs Guam treetops to kill snakes
posted by East Manitoba Regional Junior Kabaddi Champion '94 on Sep 30, 2010 - 48 comments

Queer Science

Less than two weeks after a controversial paper came to light advocating the pre-natal treatment of some female fetuses with a hormone to make their behavior more stereotypically female (previously discussed here) comes news of actual animal research on causing the opposite inclination. By knocking out the fucose mutarotase gene, scientists in South Korea have apparently created "Lesbian mice" who prefer other female mice and who resist the attempts of male mice to mate with them. Article abstract, and coverage by The Telegraph.
posted by Asparagirl on Jul 9, 2010 - 19 comments

Why should I and noble Lords trust the Executive to deal with mice when they cannot deal with the economy?

Earlier this month, there was an entertaining debate in the House of Lords about pest control in the Palace of Westminister, where the Lords meet. via kottke.org [more inside]
posted by cider on Mar 31, 2010 - 13 comments

What horror lies within

How disgusting can the inside of computer become? See now! Some people smoke near their computers. Some people secrete their chip packets inside their computer boxes. You think you can get away with it until you need someone to find out why your computer is fucked up and then.. Ah hah! Could it be.. you have an alien fetus? Mice? The detritus of your fucked up lifestyle? All living within your box? Feel bad about yourself now!
posted by h00py on Mar 2, 2010 - 70 comments

Up, up and away.

George Steinmetz takes aerial landscape photos from lightest powered aircraft in the world, a motorized paraglider (and sometimes a helicopter, a motorized hang glider, and a hot air balloon). Some of the places he has photographed include Arabia's Empty Quarter; Africa; the Dead Sea; the Altiplano; the Salt Deserts of Iran; and China. Warning: Flash based image display. [more inside]
posted by Mitheral on Dec 23, 2009 - 16 comments

It's Thursday evening in the 21st century and I still don't have a jetpack. And now mice can hover. It's unfair.

Somewhere on Earth, in a laboratory, a mouse is levitating. Science is awesome.
posted by ardgedee on Sep 10, 2009 - 63 comments

Mouse of Mirrors.

We Are All Mice Within the Lesser Vastness of the Not-Kaleidoscope. (SLYT) Structure elevates random into beautiful; individual impasse, in multiplicity, resolves into vibrant design; mirrors are weird; enter, The Duck. via Wired. (Can't find the original link any longer.)
posted by darth_tedious on Jun 21, 2009 - 13 comments

Clones produced from mice frozen for 16 years

Production of healthy cloned mice from bodies frozen at −20°C for 16 years. Mammoths next?
posted by homunculus on Nov 4, 2008 - 22 comments

The Perfect Marriage of Great Science and Great Hair

A 2007 Nobel Prize-winning breakthrough in genetics may hold the key to eliminating Trichotillomania: the gene Hoxb8 governs grooming behavior in mammals.
posted by hermitosis on Nov 7, 2007 - 12 comments

Somewhere, over the brainbow...

Brainbow. Using some very cool genetic tricks, Harvard scientists have found a way to make transgenic mice that express various mixtures of different coloured fluorescent proteins in their neurons. The result, individual brain cells with up to 90 distinct colours. Not surprisingly, this visually impressive work is in this month's issue of Nature.
posted by kisch mokusch on Nov 1, 2007 - 19 comments

A Plague of Mice

Sweet mother of Christ that is a lot of mice. The Guiness Book of World Records' official record for worst mouse infestation ever (with video) will freak the shit out of you. Literally millions of meat-eating pig devouring Australian biblical plague mice!!
posted by jonson on Sep 20, 2007 - 100 comments

mini gnarly

Radical Rodents: Chopsticks, Bunsen, Harry & Curly, surfing mice. An Australian man trained several mice on tiny surfboards. More surfing critters, a surfing dog and another one. Surfing parrot (video repeats in a couple of spots).
posted by nickyskye on Sep 3, 2007 - 17 comments

MIT reverses autism in mice

MIT researchers can reverse some symptoms of autism and mental retardation in mice by suppressing a specific enzyme. The research, conducted at the Picower Institute for Learning and Memory, is due to be posted on PNAS Online some time this week. Here is the MIT article. The specific symptoms reversed included hyperactivity, purposeless/repetitive movements, attention deficits and learning/memory challenges. The research was funded by the FRAXA Foundation, the Simons Foundation, the Wellcome Trust, and the National Institutes of Health. According to the CDC, the genetic causes treated by this particular technique (called FXS) affects one in 4,000 males and one in 6,000 females of all races and ethnic groups. I would be interested in hearing about reactions that might be taking place in the various autism-related communities.
posted by christopherious on Jun 26, 2007 - 25 comments

Hair today

Bald? A swift blow to the head might solve that problem. If nothing else, it will give you something else to worry about for a while. Note: procedure tested on mice; results in humans may vary. Possible side effects include gaping head wounds. via Slate
posted by veggieboy on May 17, 2007 - 36 comments

"I would love to see it banished off the face of the Earth."

Bisphenol A: this extremely common chemical leaches out of food packaging and plastics, and was long considered safe. But a number of recent studies link it to developmental problems and cancer in lab animals in doses far lower than the current regulatory limit. Canada and the United States both review the scientific data available in the coming months, but critics already worry the process will be corrupted by industry. Industry, of course, insists that BPA is safe.
posted by mek on Apr 7, 2007 - 32 comments

The Phantom Compass Syndrome

Hacking the Senses: The brain is far more plastic than we commonly realize. Presenting new 'senses' via the old inputs works extremely well, to the point that long-term volunteers are a little lost without their new abilities to feel magnetic north or absolute orientation. Tasting direction; feeling pictures. Fascinating stuff. In a loosely related article, genetically modified mice are able to see the full color range visible to humans, even though the last natural mouse able to see this way died out a hundred million years ago. Add the new sensors, and the brain reconfigures. [via]
posted by Malor on Apr 5, 2007 - 68 comments

From Hawaii To The Shores of Peru

Surfing Mice.
posted by fandango_matt on Feb 5, 2007 - 32 comments

What good is an army of cats without armor?

Armor for cats and rats. Well, really it's cats and mice, but that doesn't rhyme as well.Token Samurai Cat Jeff de Boer, the artist (bio here) all links have been coralized to protect the webhost
posted by filmgeek on Dec 25, 2006 - 27 comments

New Approach to Curing Chronic Viral Infections

Turning off anti-inflammatory response cures viral meningitis in mice. Chronic viral infections may one day be cured by suppression of interleukin-10 (IL-10).
posted by MonkeyC on Oct 23, 2006 - 9 comments

How do I clear my google cache again?

I'm embarassed for my mice to have to say this but ... Their testicles are HUGE, like almost as big as their heads. Good thing for humanity too, as mice testicles may provide a source of stem cells free of the usual ethical considerations.They may also hold the solutions to transplant rejection and infertility. Is there anything those fuzzy globes can't do?
posted by hindmost on Mar 28, 2006 - 22 comments

Does this mean we could make a "bat" man?

Holy Chimera - Fred Gage has spliced human brain cells into mice.
posted by sourbrew on Dec 12, 2005 - 33 comments

music, sweet music

Mouse serenade: Tim Holy and Zhongsheng Guo at Washington University School of Medicine in Missouri discover the songs of mice. Published at the Public Library of Science, Biology, (non newsie, science article). Examples of the singing, 1- shifted down 4 octaves, timing intact (MP3 file) and, 2 - shifted down 4 octaves and slowed down 16 fold. (MP3 file) (partially via)
posted by edgeways on Nov 1, 2005 - 17 comments

Mice or meece?

Ever wonder where lab mice come from? [warning: flash.]
posted by Jon-o on Oct 31, 2005 - 20 comments

Genomic Art.

Genomic Art. This lies somewhere on an interface between science and art that most never suspected existed. Check out the gallery.
Oh, and don't forget to visit the Randolph Y. Teasely Hospital - Dwayne Medical Center and it's current projects: male pregnancy, designer babies and Clyven, the world's first talking transgenic mouse.
posted by talos on Jan 22, 2003 - 3 comments

The Mars Gravity Biosatellite Project

The Mars Gravity Biosatellite Project is an unmatched international effort that pools top-notch technical talent from MIT, the University of Washington in Seattle, and the University of Queensland in Brisbane, Australia. The mission is nothing short of groundbreaking. The plan is to build a spacecraft capable of housing a small crew of mice, including pregnant females, which will simulate the gravity of Mars to determine its effects on mammalian development.
posted by David Dark on Sep 18, 2002 - 9 comments

Producing sperm on the backs of mice.

Producing sperm on the backs of mice. Well, the back of a laboratory mouse doesn't do anything - it just sits back there. Might as well put it to good use.
posted by percine on Aug 14, 2002 - 17 comments

Mice and Martians!

Mice and Martians! Mice sent to Mars, first all-rodent space crew. I like the article's style: "The crew will have no exercise wheels, however. Their motion would interfere with the centrifugal force inside the spacecraft."
posted by agregoli on Aug 6, 2002 - 3 comments

Turning on a single gene

Turning on a single gene makes mouse brains grow huge, and fold in the skull similarly to human brains. Fancy discussing Derida over tea with a rodent? more inside...
posted by daver on Jul 18, 2002 - 38 comments

3 Stench Ridden Days

3 Stench Ridden Days "For almost 3 damned days I couldn't find what was causing this god-awful smell. All of my house mates and I were convinced that there was a rotting mouse either under the floor boards or in the wall. Well I say all my house mates except for James William Ascroft-Leigh, who suggested the smell was coming from my computer. I laughed and called him a fool, claiming that the computer surley wouldn't work with a dead mouse in it..."
posted by aaronchristy on May 20, 2002 - 23 comments

Mouseageddon.

Mouseageddon.

So this is what it sounds like when mice cry.
posted by Spoon on Jan 11, 2002 - 50 comments

Making art out of a Microsoft mouse.

Making art out of a Microsoft mouse. Tails of the City is a rather cool project that entails using a Microsoft mouse as the canvas. You can bid on the works if you so desire - but just check out the fine details! [k10k]
posted by hijinx on Mar 26, 2001 - 2 comments

Ebola is for wimps!

Ebola is for wimps! Some Australian scientists were trying to come up with a mouse contraceptive vaccine, for use in pest control. And they succeeded. Unfortunately, the virus they created works by killing mice before they can breed, and killing them very very well. Oh, and it's extremely vaccine-resistant: 100% death without vaccine, 50% with. And any kid with a Li'l Johnny Gene Engineering Kit could conceivably make a human version. Anyone got some smallpox virus laying around?
posted by aaron on Jan 10, 2001 - 5 comments

Mutant Mice Drink More Alcohol, Recover Faster

Mutant Mice Drink More Alcohol, Recover Faster Now this is useful scientific research. Please alter my genes.
posted by PaperCut on Jun 1, 2000 - 1 comment

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