Last April, motivated by rumors of a Chinese paper published the next month that physically demonstrated the technical feasibility of editing human germline DNA with CRISPR by successfully modifying human embryos, a coalition of well regarded scientists assembled to address this fundamentally new ability and they called for an international summit. It was to be billed as a new Asilomar Conference on Recombinant DNA for a new age in order to lead a new global conversation on questions of whether and how to control human inheritance, which could only be dreamed of 40 years ago. This is a fundamental departure from the non-inheritable gene engineering with CRISPR covered on the blue recently. Thus, from December 1-3, the International Summit on Human Gene Editing, held as a collaborative effort between U.S. National Academy of Sciences and National Academy of Medicine, the Chinese Academy of Sciences, and The Royal Society, met to discuss the future of this technology and has come out with a clear consensus statement. [more inside]
There are fewer microbes out there than you think. New estimate reduces the number of microbes on Earth by around half. [more inside]
In a recent paper published in Nature Hansen et al. show the efficacy of their unusual vaccine strategy against SIVMAC239 in rhesus macaques. While the goal is not necessarily to produce a human vaccine against HIV using this exact strategy, this paper is now reigniting the debate over the progression of HIV infections and the mechanism(s) by which the virus skirts the human immune system.