Dr. Henry Marsh has performed 400 "awake craniotomies" -- a surgical procedure he helped pioneer -- in which a specific kind of brain tumor that looks just like the brain itself is identified through electric stimulation and removed. Without surgery, 50 percent of patients die within 5 years; 80 percent within 10 years, and the operation can prolong their lives by 10 to 20 years or more. He was profiled in a 2007 documentary: The English Surgeon as well as this article by Karl Ove Knausgaard: The Terrible Beauty of Brain Surgery. Images in some links in this post may be disturbing to some viewers.
The Lost Girls: 'Misdiagnosed, misunderstood or missed altogether, many women with autism struggle to get the help they need.' Part of Spectrum's Sex/Gender in Autism special report. [more inside]
The Last Day of Her Life. When Cornell psychology professor Sandy Bem found out she had Alzheimer’s, she resolved that before the disease stole her mind, she would kill herself. The question was, when? [more inside]
She started by diving into PubMed—an online search engine for biomedical papers—hunting down everything she could on Charcot-Marie-Tooth. She hoped that her brief fling with a scientific education would carry her through. But with pre-med knowledge that had been gathering dust for 30 years and no formal training in genetics, Kim quickly ran head first into a wall of unfamiliar concepts and impenetrable jargon. “It was like reading Chinese,” she says.
"Postpartum depression isn’t always postpartum. It isn’t even always depression. A fast-growing body of research is changing the very definition of maternal mental illness, showing that it is more common and varied than previously thought." ‘Thinking of Ways to Harm Her’ and "After Baby, an Unraveling". [more inside]
On November 30, the Tampa Bay Times published a sympathetic profile of Spring Hill, FL resident Gretchen Molannen: "Persistent genital arousal disorder brings woman agony, not ecstasy." Her condition, also known as PGAD, is a rare sexual disorder (not recognized by the DSM,) 'characterized by spontaneous, persistent, unwanted sexual arousal unrelated to feelings of sexual desire.' The Times reported that Ms. Molannen's condition had virtually destroyed her personal and professional life and led to several suicide attempts. One day after the article was published, she successfully committed suicide. [more inside]
My Above-Average Stroke. From November 2010, Garrison Keillor writing about the stroke he suffered in 2009. [more inside]
The "Still Face" Paradigm (YT video) designed by Dr. Edward Tronick of Harvard and Childrens Hospital’s Child Development Unit, is an experiment which shows us how a 1-year old child will react to a suddenly unresponsive parent. It allows us to understand how a caregiver's interactions and emotional state can influence many aspects of an infant's social and emotional development. [more inside]
"We were concerned that the study would raise a lot of controversy and be misused," Pardo said. "We were right." Some practitioners treat autistic children with the anti-inflammatory intravenous immunoglobulin, citing a study by Carlos Pardo, et al. showing inflammation in the brains of deceased autistic patients. Pardo: "modulators of immune reactions (e.g. intravenous immunoglobulins, IVIG) WOULD NOT HAVE a significant effect." Others, following the work of Simon Baron-Cohen on autism and the male brain, treat autistic children with testosterone inhibitors, a prospect which Baron-Cohen says "fills me with horror." Another anti-inflammatory treatment, hyperbaric therapy, is supported by one recent clinical trial, but looks bad in another. Side effects include horrible death by fire. (via the Chicago Tribune)
Does american football unavoidably lead to brain damage over time? Does a culture favoring perseverance at the expense of well being begin in high school?
We've discussed trepanation, the boring of holes in the head as practiced in antiquity and by a fringe do it yourself-ers, before. There now seems to be research indicating that the procedure may have medical merit, and even help stave off age related cognitive decline. This curious research brought to you by the Beckly Foundation which "promotes the investigation of consciousness and its modulation from a multidisciplinary perspective" and has a sweet logo.