Maia Szalavitz [mefi's own maias] talks about her new book, Unbroken Brain: A Revolutionary New Way of Understanding Addiction on Fresh Air with Terry Gross (transcript) - "We have this idea that if we are just cruel enough and mean enough and tough enough to people with addiction, that they will suddenly wake up and stop, and that is not the case."
Magic Mushroom Drug Lifts Depression in Human Trial - "The findings show that more research in this field is now needed. 'This is the first time that psilocybin has been investigated as a potential treatment for major depression', says lead author Dr Robin Carhart-Harris, Imperial College London."
Could depression be an infectious disease? Might hallucinogenic mushrooms be an effective treatment for depression (New York Times link)? Do antipsychotic drugs hinder long-term recovery from episodes of schizophrenia?
How Tripping On Mushrooms Changes The Brain - "New research [pdf] suggests that psilocybin, the main psychoactive ingredient in magic mushrooms, sprouts new links across previously disconnected brain regions, temporarily altering the brain's entire organizational framework." [more inside]
Cognitive behavioural therapy is the best-studied form of psychotherapy. But researchers are still struggling to understand why it works (Single Link Nature.com). [more inside]
Based on a comparison of suicide rates at sea level and at areas above 2,000 feet, living at a high altitude may make people 30% more likely to commit suicide. Neuroscientist Perry Renshaw believes that it's due to the impact of altitude on the brain.
A pilot study testing for statistically significant blood biomarkers found in early-onset MDD: "Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression" [PDF], published by the online, open source journal Translational Psychiatry**, April 2012, Volume 2. [more inside]
A gene variant associated with serotonin transport (STG) , and normally associated with depression is strangely more prevalent, but also less likely to induce depression in collectivistic East Asian cultures. The study took data from 29 countries, and found a consistent trend towards this same genetic variant being strongly associated with episodes of major depression in Western cultures.
A review of the current state of gender based brain research shows that women and men differ both in the way their brains are constructed and in how they function.
..correlation between brain region size in adults and sex steroid action in utero suggests that at least some sex differences in cognitive function do not result from cultural influences or the hormonal changes associated with puberty--they are there from birth.Treatment for such things as schizophrenia and depression will likely have gender specific variations in the future. Previously, brain research that examined gender differences was considered controversial because it was argued that the results might give rise to more sex discrimination against women. That view may be changing.