5 posts tagged with psychiatry and Medication. (View popular tags)
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Falling STAR*D?

Falling STAR*D?: It is common practice for psychiatrists to switch depressive patients between different antidepressants if their current drug does not evince a symptomatic response. Despite clinical wisdom supporting this, little empirical, controlled evidence exists to direct “switching” protocols (e.g. if a patient with Z characteristics is on drug X, is it usually better to switch to drug A, B, or C? Will switching help at all?) in the psychopharmacological treatment of depression. The NIMH-funded STAR*D (Sequenced Alternatives to Relieve Depression) study aimed to address these questions of treatment direction in a very large (n>4000), “real-world” sample using a multi-phase treatment plan with different drugs (and cognitive therapy) at every step to maximize chances of eventual remission. Overall, the NIMH reported that about 67% of patients eventually achieved remission, with few differences in effectiveness between different types of treatment at each step. However, researchers and commentators have raised concerns regarding inconsistent reporting of outcomes, after-the-fact changes in study design and analysis, and other issues that may have inflated, partially invalidated, or misrepresented widely reported treatment outcomes. These inequities may also have implications for the secondary moderator analyses (i.e. does trait A predict switching to X or Y is better?) that were a major reason for the study. [more inside]
posted by Keter on Jan 14, 2012 - 12 comments

 

Placebos

Placebos Are Getting More Effective. Drugmakers Are Desperate to Know Why.
posted by homunculus on Aug 25, 2009 - 106 comments

Coming of Age on Antidepressants

Who Are We? Coming of Age on Antidepressants. [Via Mind Hacks.] [more inside]
posted by homunculus on Apr 16, 2008 - 49 comments

The Japanese Gallery of Psychiatric Ar

The Japanese Gallery of Psychiatric Art. Images from Japanese psychiatric medication advertisements: 1956-2003 (via Absent without leave)
posted by matteo on Mar 9, 2005 - 14 comments

Take 2 Thorazine & call me in the morning.

The American Gallery of Psychiatric Art. 'Sanity For Sale: 1960-2000'. Magazine advertisements for psychiatric medications in the latter half of the twentieth century.
posted by eyebeam on Jul 23, 2003 - 15 comments

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