New Ebola vaccine shows 100% success rate in clinical trial. Today the World Health Organization has announced that the rVSV-ZEBOV vaccine had a 100% success rate in preventing onset of the disease if administered within 10 days of exposure (n=4,000). In response to the current outbreak in West Africa that has afflicted over 27,000 and killed over 11,000, this collaborative effort led by the WHO pushed the vaccine through a process that usually takes more than a decade in just 12 months. Official paper from The Lancet here (pdf).
[Eleven] days ago, The New Yorker’s Daily Comment blog published an essay by Michael Specter titled “What Young Gay Men Don’t Know About Aids,” in which Specter points to the increase of “unprotected anal intercourse among gay men,” claims that “the rates of HIV infection will surely follow,” and then identifies the cause of this shift as the ignorance of my generation, who weren’t around to see the AIDS epidemic for themselves. The piece is a call to arms of sort, stating the need for increased public funding for HIV/AIDS prevention, and concludes by quoting Larry Kramer’s famous 1983 warning, “1,112 and Counting.” It’s a familiar argument—one that, in my lifetime, I have heard repeated ad nauseam and, I fear, largely misses what AIDS means to me and many other young gay men.
291 diseases and injuries + 67 risk factors + 1,160 non-fatal complications = 650 million estimates of how we age, sicken, and die
As humans live longer, what ails us isn't necessarily what kills us: five data visualizations of how we age, sicken, and die. Causes of death by age, sex, region, and year. Heat map of leading causes and risks by region. Changes in leading causes and risks between 1990 and 2010. Healthy years lost to disability vs. life expectancy in 1990 and 2010. Uncertainties of causes and risks. From the team for the massive Institute for Health Metrics and Evaluation Global Burden of Diseases, Injuries, and Risk Factors Study 2010. [more inside]
Biocaster is an ontology-based global health monitoring system that monitors and maps disease outbreaks through internet-based news aggregation and social media. [more inside]
Mercenary Epidemiology: Data Reanalysis and Reinterpretation for Sponsors With Financial Interest in the Outcome. (.pdf link) When should scientists be required to release their raw data for (potentially hostile) re-analysis? A letter to the editors of Annals of Epidemiology from David Michaels, Ph.D., MPH, public health blogger, author of the book Doubt Is Their Product, and, as of December 2009, the Assistant Secretary of Labor for OSHA, unanimously confirmed by the Senate despite the dismay of some. Michaels interviewed at Science Progress about Doubt Is Their Product (podcast, with transcript.)
Haunted by a truly global epidemic, perhaps it is time to consider the effects of globalization on the spread of diseases like AIDS. In addition to making it easier for disease to achieve global prevalence, global economics reduce funding for public health by placing treatment emphasis on those who can pay for their drugs, and, in the case of AIDS, may also encourage pharmaceutical companies to pursue expensive life-long 'treatments' rather than cures. Furthermore, younger, economically depressed members of the global economy are wholly dependent on the whim of richer nations for their well-being in the face of devastating epidemics. In this case, it seems that the global marketplace has failed to be the holy grail it is so often presented as.
Three people may have contracted foot-and-mouth, though all the tests aren't in. This is the first time this has occured during the current outbreak. I think the most, er, interesting thing is exactly how one of the guys got it.