"Researchers found that failing to publish negative findings inflated the reported effectiveness of all 12 of the antidepressants studied." See also: Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature.
posted on Jan 17, 2008 - View this thread

Ketamine has been found to "significantly" improve symptoms of depression by influencing glutamate levels in the brain. A Forbes article notes that 70% of patients say improvement, and up to 29% were "nearly symptom free within one day". However, research into the effects of ketamine on depression is not exactly new.
posted on Aug 9, 2006 - View this thread

Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature
posted on Nov 8, 2005 - View this thread

When drug companies hide data.

"The attorney general's civil suit accuses the drug giant GlaxoSmithKline of committing fraud by concealing negative information about Paxil, a drug used to treat depression. The suit says that the company conducted five clinical trials of Paxil in adolescents and children, yet published only one study whose mixed results it deemed positive. The company sat on two major studies for up to four years, although the results of one were divulged by a whistle-blower at a medical conference in 1999 and all of the studies were submitted to the Food and Drug Administration in 2002 when the company sought approval for new uses of Paxil. At that time it became apparent that Paxil was no more effective than a placebo in treating adolescent depression and might even provoke suicidal thoughts.

My Dad was on Paxil until 26 days ago..... that's when he shot himself.
posted on Jun 6, 2004 - View this thread

Stanford links genius and manic depression... I feel SO much better now... (via FARK)
posted on May 23, 2002 - View this thread