124 posts tagged with science and medicine. (View popular tags)
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First Gene Therapy Successful Against Aging-Associated Decline: Mouse Lifespan Extended Up to 24% With a Single Treatment A new study consisting of inducing cells to express telomerase, the enzyme which -- metaphorically -- slows down the biological clock -- was successful. The research provides a "proof-of-principle" that this "feasible and safe" approach can effectively "improve health span." [article]
posted by T.D. Strange on May 15, 2012 - 97 comments

The emergence of a citation cartel. "Cell Transplantation is a medical journal published by the Cognizant Communication Corporation of Putnam Valley, New York. In recent years, its impact factor has been growing rapidly. In 2006, it was 3.482. In 2010, it had almost doubled to 6.204. When you look at which journals cite Cell Transplantation, two journals stand out noticeably: the Medical Science Monitor, and The Scientific World Journal. According to the JCR, neither of these journals cited Cell Transplantation until 2010. Then, in 2010, a review article was published in the Medical Science Monitor citing 490 articles, 445 of which were to papers published in Cell Transplantation. All 445 citations pointed to papers published in 2008 or 2009 — the citation window from which the journal’s 2010 impact factor was derived. Of the remaining 45 citations, 44 cited the Medical Science Monitor, again, to papers published in 2008 and 2009. Three of the four authors of this paper sit on the editorial board of Cell Transplantation. Two are associate editors, one is the founding editor. The fourth is the CEO of a medical communications company." (from Scholarly Kitchen, via Andrew Gelman.)
posted by escabeche on May 15, 2012 - 26 comments

Are bias and fraud damaging the existing public trust in scientific and medical research? (previously) [more inside]
posted by jeffburdges on May 13, 2012 - 35 comments

"Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets." After an extensive, months-long debate, one of two controversial papers showing ways the H5N1 "avian" influenza virus could potentially become transmissible in mammals with only 3 or 4 mutations was published in Nature today. The journal included an editorial on the merits and drawbacks of "publishing risky research" with regard to biosafety. The debate included an unprecedented recommendation by The US National Science Advisory Board for Biosecurity (NSABB) to block publication -- a decision they later reversed. (Via: 1, 2) Nature's special report has additional articles, including interviews with the teams behind both papers.
posted by zarq on May 3, 2012 - 37 comments

Since 2000, the Centers for Disease Control and Prevention has based its estimates of how many children in the United States have autism on surveillance reports from its Autism and Developmental Disabilities Monitoring Network. Every two years, researchers count how many 8-year-olds have an autism spectrum disorder in about a dozen communities across the nation. According to a new report released by the CDC yesterday, (pdf), the latest data estimate that 1 in 88 American children has some form of autism spectrum disorder. (1 in 54 boys and 1 in 252 girls.) That's a 78% increase compared to a decade ago. The report, which analyzed data from 2008, indicates a 23 percent rise in diagnoses of ASDs over a two-year period. (Last link has autoplaying video)
posted by zarq on Mar 30, 2012 - 42 comments

In March 2010, a pair of health inspectors responding to multiple tips paid a three-day visit to the factory headquarters of the Poly Implant Prothese (PIP) company, a leading international maker of breast implants. On their second day, the inspectors found something odd: six discarded plastic containers of Silopren, a liquid silicone designed for industrial, not medical use, lined up along the outside wall of the production site. The lead inspector estimated they had contained nearly 9 tons of liquid silicone. It now appears as if between 300,000 and 400,000 women throughout the world may have received potentially toxic, faulty breast implants containing ingredients never clinically tested on humans, manufactured and distributed by a company that knowingly deceived regulators, suppliers, distributors, medical professionals and ultimately, patients. Reuters photographer's Blog: Operating on an implant scandal. (Last link NSFW, graphic images that contain nudity.) [more inside]
posted by zarq on Feb 18, 2012 - 58 comments

"I'm banned," he says. "By whom?" I ask. "My landlord," he says. "And the Swedish Radiation Safety Authority." Jon Ronson on DIY science.
posted by fearfulsymmetry on Feb 4, 2012 - 33 comments

Qualcomm and the X Prize Foundation have launched a new contest: Envision and build the equivalent of Star Trek's medical tricorder, a portable health monitoring device that can remotely diagnose patients. The winner will receive $10 million. [more inside]
posted by zarq on Feb 2, 2012 - 85 comments

"I would point out to you that medical explanations are modern. That Americans today want medical explanations for things that in the 19th century would have been explained by hysteria, and in the 18th century would have been explained by religious conversion experiences in the context of the Great Awakening, when people were having these types of fits, and in the 17th century by witchcraft."

posted by empath on Jan 30, 2012 - 54 comments

In 2002, Doug Monroe placed his parents in assisted living. A decade later, he's looking back at "the weighty financial and emotional costs that come with a parent's immortality": The Long Goodbye.
posted by zarq on Jan 25, 2012 - 85 comments

Day at Night was an interview series on the public television station of the City University of New York that aired from 1973-4. CUNY TV is in the process of digitizing and uploading the 130 episodes that were produced, with 46 done so far. The episodes are just under half an hour in length. Among the people interviewed by host James Day are author Ray Bradbury, actress Myrna Loy, medical researcher Jonas Salk, singer Cab Calloway, writer Christopher Isherwood, nuclear scientist Edward Teller, comedian Victor Borge, tennis player Billie Jean King, linguist and activist Noam Chomsky, composer Aaron Copland, actor Vincent Price and boxer Muhammad Ali.
posted by Kattullus on Jan 16, 2012 - 6 comments

Falling STAR*D?: It is common practice for psychiatrists to switch depressive patients between different antidepressants if their current drug does not evince a symptomatic response. Despite clinical wisdom supporting this, little empirical, controlled evidence exists to direct “switching” protocols (e.g. if a patient with Z characteristics is on drug X, is it usually better to switch to drug A, B, or C? Will switching help at all?) in the psychopharmacological treatment of depression. The NIMH-funded STAR*D (Sequenced Alternatives to Relieve Depression) study aimed to address these questions of treatment direction in a very large (n>4000), “real-world” sample using a multi-phase treatment plan with different drugs (and cognitive therapy) at every step to maximize chances of eventual remission. Overall, the NIMH reported that about 67% of patients eventually achieved remission, with few differences in effectiveness between different types of treatment at each step. However, researchers and commentators have raised concerns regarding inconsistent reporting of outcomes, after-the-fact changes in study design and analysis, and other issues that may have inflated, partially invalidated, or misrepresented widely reported treatment outcomes. These inequities may also have implications for the secondary moderator analyses (i.e. does trait A predict switching to X or Y is better?) that were a major reason for the study. [more inside]
posted by Keter on Jan 14, 2012 - 12 comments

Trials and Errors. Jonah Lehrer's latest piece in Wired is a sort of sequel to his earlier article in the New Yorker on the decline effect (previously). Where that article focused on the institutional factors interfering with the accumulation of truth, this one focuses on the philosophical issues of causation and correlation in modern science. [Via]
posted by homunculus on Jan 5, 2012 - 22 comments

How can we better understand the interplay of nature and nurture in determining our personalities, behavior, and vulnerability to disease? Perhaps we should be looking at identical twins. (National Geographic January 2012 cover story) [more inside]
posted by zarq on Dec 19, 2011 - 89 comments

Even a little too much Tylenol over a few days can cause a liver failure. Paracetamol or acetaminophen, active ingredient of such over-the-counter painkillers as Tylenol, Panadol, Anacin-3 and many, many others, is considered safe - and it is, in prescribed doses. But even a single overdose can lead to liver failure despite treatment, and then only a liver transplant can avert a fatal outcome. [more inside]
posted by hat_eater on Nov 27, 2011 - 108 comments

The US Center for Disease Dynamics, Economics and Policy runs a non-profit, Extending the Cure, which conducts policy research to extend antibiotic effectiveness, and ResistanceMap, which generates interactive analysis tools and maps regarding antibiotic use in Europe and the US. The most recent ResistanceMap visualizations indicate that the US Southeast overprescribes antibiotics at a high rate compared with the rest of the country. Science journalist / "Superbug" blogger Maryn McKenna speculates (while acknowledging that correlation ≠ causation,) that the map might also indicate a link between overuse of antibiotics, obesity, diabetes and stroke. [more inside]
posted by zarq on Nov 25, 2011 - 30 comments

Jane Pratt (formerly of Sassy Magazine and her eponymous Jane,) launched a website for women: xojane, earlier this year. Last week the site's Health and Beauty Director wrote a blog post explaining that she never uses condoms, birth control pills, or other contraception (for fear of becoming fat) and instead relies on the emergency contraceptive Plan B to prevent pregnancy. And a segment of the internet exploded. (Her responses to some of the comments seem a bit clueless for someone with her title.) Critics have noted that the post was filled with "ignorant" "inaccuracies and misconceptions" about womens' health, sex, Plan B and other forms of birth control. [more inside]
posted by zarq on Oct 21, 2011 - 104 comments

Body suit may soon enable the paralyzed to walk. "In a busy lab at Duke University, Dr. Miguel Nicolelis is merging brain science with engineering in a bid to create something fantastical: a full-body prosthetic device that would allow those immobilized by injury to walk again. On Wednesday, Nicolelis and an international group of collaborators declared that they had cleared a key hurdle on the path toward that goal, demonstrating they could bypass the body's complex network of nerve endings and supply the sensation of touch directly to the brains of monkeys."
posted by homunculus on Oct 6, 2011 - 37 comments

An experiment done in the 1990s exposed children to various levels of lead. The lawsuit filed in 2001 by the parents of over 100 participants accuses the Kennedy Krieger Institute that the scientists knowingly used the kids as test subjects in toxic dust control study. [more inside]
posted by hat_eater on Sep 19, 2011 - 51 comments

Gamers solve molecular puzzle that baffled scientists. The structure of a protein causing AIDS in rhesus monkeys had not been discovered in 15 years of attempts. Players of a videogame did it in ten days. Foldit, the game in question. Abstract. Previously, previously.
posted by East Manitoba Regional Junior Kabaddi Champion '94 on Sep 18, 2011 - 54 comments

'The stories about epidemics that are told in the American press—their plots and tropes—date to the 1920's, when modern research science, science journalism, and science fiction were born.' This is the story of how the media back then (January, 1930) helped fuel fears about a parrot-fever pandemic, and the subsequent public backlash. (Via) [more inside]
posted by zarq on Sep 11, 2011 - 24 comments

Biomedical Ephemera, or, a Frog for your Boils is "A blog for all biological and medical ephemera, from the age of Abraham through the era of medical quackery and cure-all nostrums. Sometimes featuring illustrations of diseases and conditions of the times, sometimes fascinating ephemeral medical equipment, and sometimes clippings and information about the theories themselves." The archive page is also a useful starting point. via Things Magazine.
posted by Rumple on Aug 29, 2011 - 8 comments

Last week Johnson & Johnson announced that it is lowering the maximum daily dose for single-ingredient Extra Strength Tylenol from 8 to 6 pills per day (from 4,000 to 3,000 mg). [more inside]
posted by hat_eater on Aug 4, 2011 - 54 comments

At the beginning of last month, Scientific American unveiled a new network of 47 blogs with 55 bloggers. Their latest posts can be found here. [more inside]
posted by zarq on Aug 2, 2011 - 15 comments

Hesperian is a non-profit publisher of books and newsletters for community-based health care, mostly aimed at the third world. Their first book, Where There Is No Doctor, A Village Health Handbook, has been translated into 88 languages and is one of the most widely used training and work manuals for community health care in the world. They have now made 20 of their publications available for free download, many of which can now also be browsed online through their website using an "Ebrary" in-browser interface. [more inside]
posted by zarq on Jul 26, 2011 - 15 comments

The Triumph of New-Age Medicine "Medicine has long decried acupuncture, homeopathy, and the like as dangerous nonsense that preys on the gullible. Again and again, carefully controlled studies have shown alternative medicine to work no better than a placebo. But now many doctors admit that alternative medicine often seems to do a better job of making patients well, and at a much lower cost, than mainstream care—and they’re trying to learn from it." [more inside]
posted by zarq on Jun 15, 2011 - 278 comments

Recently, 8-year-old Precious Reynolds became the sixth person in history to survive rabies without a vaccine. A few years back, Extraordinary People put out a documentary (1 2 3) on the first person to beat the only viral disease that hides itself completely from one's immune system.
posted by gman on Jun 14, 2011 - 56 comments

"Street Anatomy obsessively covers the use of human anatomy in medicine, art, and design."
posted by OmieWise on Jun 11, 2011 - 5 comments

The Revolutionary New Birth Control Method for Men. Link NSFW. [more inside]
posted by zarq on May 31, 2011 - 106 comments

The Burns Archive is a collection of over 700,000 historical photographs that document disturbing subject matter: obsolete medical practices and experiments, death, disease, disasters, crime, revolutions, riots and war. Newsweek posted a select gallery this past October, as well as a video interview and walk-through with curator and collector Dr. Stanley B. Burns, a New York opthalmologist. (Via) (Content at links may be disturbing to some.) [more inside]
posted by zarq on Apr 26, 2011 - 15 comments

The New Biology - Eric Schadt's quest to upend molecular biology and open source it. (via)
posted by kliuless on Apr 9, 2011 - 35 comments

One in every 8 babies born in the US is premature. A new study (pdf/via) published online Wednesday in Ultrasound in Obstetrics and Gynecology indicates that vaginal progesterone gel can help women who are pregnant for the first time and at risk of premature birth extend their pregnancies, reduce potential complications and boost the health of their newborns. [more inside]
posted by zarq on Apr 8, 2011 - 18 comments

"One day a little boy came up, he must have been about four and he saw me taking off my (prosthetic) legs and he started with the 'why' questions, you know, 'why haven't you got any legs', etc. And I said 'have you heard of The Little Mermaid?' and he said 'yes' and I said 'I'm a mermaid' and he got this look on his face and he said 'wow that's cool' and ran off to tell his dad.

I'll have to turn up to that beach again sometime with my tail - just in case he's there."
Weta Digital are the special effects team behind the costumes, weapons and creatures of the Lord of the Rings movies, Avatar and even a sonic screwdriver prop that could be making an appearance on the next season of Doctor Who. In 2009, they created a fully functional mermaid tail pro bono for Nadya Vessey, an Auckland woman who is a double leg amputee. Video News Report: 1, 2.
posted by zarq on Apr 5, 2011 - 37 comments

Epidemiology: Study of a lifetime. "In 1946, scientists started tracking thousands of British children born during one cold March week. On their 65th birthday, the study members find themselves more scientifically valuable than ever before." [more inside]
posted by zarq on Mar 21, 2011 - 7 comments

It was Alex St. Martin's gory musket injury that paved the way for cow fistulation, a hands-on method to explore the inner workings of bovine digestion.
posted by Chinese Jet Pilot on Mar 18, 2011 - 58 comments

The Billionaire Who Is Planning His 125th Birthday. Also: The Die-Later Diet [more inside]
posted by zarq on Mar 6, 2011 - 66 comments

The Royal Society's lost women scientists. Women published in the Royal Society, 1890-1930. Most influential British women in the history of science. Women at the Royal Observatory Greenwich. Heroines of Science. Women Biochemists, 1906-1939. Women in Science. Previously: The Women of ENIAC.
posted by mediareport on Jan 12, 2011 - 9 comments

"It is only fitting that the story of the brain should be a visual one, for the visuals had the ancients fooled for millenniums. The brain was so ugly that they assumed the mind must lie elsewhere. Now those same skeletal silhouettes glow plump and brightly colored, courtesy of a variety of inserted genes encoding fluorescent molecules. A glossy new art book, “Portraits of the Mind,” hopes to draw the general reader into neuroscience with the sheer beauty of its images." Slide Shows: The Beautiful Mind and Portraits of the Mind [more inside]
posted by zarq on Dec 2, 2010 - 6 comments

I am trained and experienced in animal testing, and I am not ashamed of this fact. There, I’m out.
posted by shiu mai baby on Oct 29, 2010 - 93 comments

An excerpt from Stephen Hawking's and Leonard Mlodinow's new book The Grand Design.
posted by lauratheexplorer on Sep 10, 2010 - 86 comments

A stroke happens when blood flow is blocked to a part of the brain. The effects can be devastating. It turns out we might be able to prevent the damage with a simple tickle of the whiskers. [more inside]
posted by nomisxid on Jul 14, 2010 - 36 comments

Sir, Your Liver Is Ready: Behind the Scenes of Bioprinting (Previously on MeFi)
posted by zarq on Jul 12, 2010 - 9 comments

Vanessa Mae Nicholson is one of Britain’s most successful young musicians. A classical violinist and former child prodigy who self-describes her crossover style as "violin techno-acoustic fusion," her fans praise her modern creativity and frenetic, lightning-fast riffs. But is her talent learned or genetic? Documentary from BBC1 in 2008: Vanessa Mae - The Making of Me: 1, 2, 3, 4, 5, 6. [more inside]
posted by zarq on Jun 21, 2010 - 18 comments

"EIZO High End Monitors Medical Imaging" presents: Pin-Up 2010, an x-ray pinup calendar. (Possibly NSFW)
posted by zarq on Jun 16, 2010 - 46 comments

"During World War I, the [US] Army lost 7 million person-days and discharged more than 10,000 men because they were ailing from STDs. Once Penicillin kicked in in the mid-1940s, such infections were treatable. But as a matter of national security, the military started distributing condoms and aggressively marketing prophylactics to the troops in the early 20th century." [more inside]
posted by zarq on Jun 1, 2010 - 45 comments

New Scientist Special Report: Living in Denial. Includes articles by Michael Shermer, founding publisher of Skeptic Magazine [more inside]
posted by zarq on May 28, 2010 - 37 comments

Are the Rules That Determine Who Can Donate Blood Discriminatory? Canadian AIDS researchers Dr. Mark Wainberg and Dr. Norbert Gilmore say that while the ban on blood donation from men who have sex with other men may have been ethically and scientifically justified in the 1980's, it no longer makes sense. (CMAJ.) Even though the US FDA reaffirmed their long-standing ban in 2007, they plan to revisit the policy in June. [more inside]
posted by zarq on May 26, 2010 - 69 comments

Followup to this post: A US District Court has ruled that Myriad Genetic's patents on breast cancer genes BRCA1 and BRCA2, which allow them to hold exclusive rights to a widely used genetic test for inherited breast and ovarian cancer susceptibility, are invalid. Genomics Law Report analyzes the ruling in two posts. The decision is likely to be challenged in a legal appeal — but if upheld, it could have huge implications for the biotechnology industry. [more inside]
posted by zarq on Mar 31, 2010 - 51 comments

The NHS Behind the Headlines site gives the scientific facts behind the medical stories making the news.
posted by chorltonmeateater on Mar 22, 2010 - 24 comments

The "Still Face" Paradigm (YT video) designed by Dr. Edward Tronick of Harvard and Childrens Hospital’s Child Development Unit, is an experiment which shows us how a 1-year old child will react to a suddenly unresponsive parent. It allows us to understand how a caregiver's interactions and emotional state can influence many aspects of an infant's social and emotional development. [more inside]
posted by zarq on Mar 15, 2010 - 22 comments

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