The history of humanity’s grand sweep around the world is recorded in our genes and genealogies, our art and artifacts, our literature and languages. It’s also written in the legions of tiny mites that live, eat, crawl, and have sex on your face.
"Immigration to my country harms me, it harms my family, it harms my people. Whoever invites or welcomes immigrants to Europe and Germany is my enemy,” says bioinformatician Gangolf Jobb, who has responded to the Syrian migrant crisis by revoking the license for his Treefinder software, one tool (among many) that help measure and visualize the evolutionary distances between organisms. [more inside]
"The patient tested negative for HIV, tuberculosis, lime disease, syphilis, coccidioides, histoplasma and cryptococcus." After four years of MRIs, a person's mysterious headaches, seizures and altered sense of smell and memory are diagnosed as a tapeworm growing throughout his brain.
In February 2008, Yehia Gad sequenced Tutankhamun's genes in front of a documentary crew from the Discovery Channel. Jo Marchant writes about the previous work studying his tomb and remians and the unfortunate timing of the last study. (King Tut Previously) [more inside]
The Xenotext Experiment is Christian Bök's [Previously],"nine-year long attempt to create an example of “living poetry.” I have been striving to write a short verse about language and genetics, whereupon I use a “chemical alphabet” to translate this poem into a sequence of DNA for subsequent implantation into the genome of a bacterium (in this case, a microbe called Deinococcus radiodurans—an extremophile, capable of surviving, without mutation, in even the most hostile milieus, including the vacuum of outer space)." [Via] [more inside]
Neandertals are the closest ancestral relatives to modern humans. Today, Nature published a special report on the Neandertal genome, for which a draft sequencing of three billion nucleotides has been completed. This high-throughput sequencing project shows how the genetic relationship between Neandertals and modern Europeans and Asians suggests localized interbreeding between the two species roughly 40-80,000 years ago, complicating the common "out-of-Africa" story of how modern humans originated. Additional research extends this low-coverage, first-pass sequencing with a microarray approach that uncovers specific differences between the human and Neandertal genomes.
I.B.M. Joins Pursuit of $1,000 Personal Genome The target is remarkable given that the original Human Genome Project successfully sequenced the first genome less than ten years ago and cost roughly $500 million to $1 billion. Advances in sequencing technology puts Moore's Law to shame: "In the last four to five years, the cost of sequencing has been falling at a rate of tenfold annually, according to George M. Church, a Harvard geneticist. In a recent presentation in Los Angeles, Dr. Church said he expected the industry to stay on that curve, or some fraction of that improvement rate, for the foreseeable future." [more inside]
How to Sequence a Genome [Flash. H/T to Jay]. Visualization of the process of genetic sequencing. Posted on the Nova website in conjunction with their show, Cracking the Code of Life, hosted by Robert Krulwich [Wiki].
Put down that McChicken sandwich, punk, and back away slowly. OK, now run! The chicken is T. Rex's closest known living relative.