Much easier to put together custom DNA
An interdisciplinary study led by Dr Ali Tavassoli, a Reader in chemical biology at the University of Southampton, has shown for the first time that 'click chemistry' can be used to assemble DNA that is functional in human cells, which paves the way for a purely chemical method for gene synthesis.
Writing in Angewandte Chemie International Edition Dr Tavassoli's team and his collaborators, Dr Jeremy Blaydes and Professor Tom Brown, show that human cells can still read through strands of DNA correctly despite being stitched together using a linker not found in nature.
posted by aleph
on Feb 9, 2014 -
I just finished up reading The Turk
by Tom Standage (briefly mentioned in passing here
) a biography of the chess-playing automaton that toured Europe and later the Americas during the pivotal transition from the 18th to the 19th century. The Automaton was invented as an exercise in national pride by Wolfgang von Kempelen,
who considered it a trifle compared to his experiments with mechanical speech synthesis.
As a celebrity, the automaton had historic encounters with Benjamin Franklin, Napoleon, Beethoven, Philidor
and Charles Babbage, and fictional encounters with the monarchs Catherine the Great, George III and Frederick II. Standage credits it with influencing the development of the Difference Engine
, the power loom, Poe's mystery stories
, and Barnum's manipulation of the press.
The myths surrounding have even caught James Randi
, who seems to have been unaware of a colleague's reconstruction
based on notes from the last owner.
posted by KirkJobSluder
on Sep 21, 2005 -