Humans 2.0 - "With CRISPR, scientists can change, delete, and replace genes in any animal, including us. Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis. One group has replaced a mutation that causes cataracts; another has destroyed receptors that H.I.V. uses to infiltrate our immune system." [more inside]
Sapiens: A Brief History of Humankind by Yuval Noah Harari - "The book delivers on its madly ambitious subtitle by in fact managing to cover key moments in the developmental history of humankind from the emergence of Homo Sapiens to today's developments in genetic engineering." Also btw, check out Harari on the myths we need to survive, re: fact/value distinctions and their interrelationships.
The CRISPR Revolution [ungated: 1,2,3] - "Biologists continue to hone their tools for deleting, replacing or otherwise editing DNA and a strategy called CRISPR has quickly become one of the most popular ways to do genome engineering. Utilizing a modified bacterial protein and a RNA that guides it to a specific DNA sequence, the CRISPR system provides unprecedented control over genes in many species, including perhaps humans. This control has allowed many new types of experiments, but also raised questions about what CRISPR can enable." [more inside]
The harsh environments of our neighboring planets will require proper attire, with 3D-printed, biological fashions that, in the words of the designer Neri Oxman, "blur the boundary between the environment and ourselves." Oxman's other recent work explores similar lines of utility with her organic, post-industrial aesthetic: some of it disturbing and some sublime.
You invest so much in it, don't you? It's what elevates you above the beasts of the field, it's what makes you special. Homo sapiens, you call yourself. Wise Man. Do you even know what it is, this consciousness you cite in your own exaltation? Do you even know what it's for?Dr. Peter Watts is no stranger to MetaFilter. But look past his sardonic nuptials, heartbreaking eulogies, and agonizing run-ins with fascists (and fasciitis) and you'll find one of the most brilliant, compelling, and disquieting science fiction authors at work today. A marine biologist skilled at deep background research, his acclaimed 2006 novel Blindsight [full text] -- a cerebral "first contact" tale led by a diverse crew of bleeding-edge post-humans -- is diamond-hard and deeply horrifying, wringing profound existential dread from such abstruse concepts as the Chinese Room, the Philosophical Zombie, Chernoff faces, and the myriad quirks and blind spots that haunt the human mind. But Blindsight's last, shattering insight is not the end of the story -- along with crew/ship/"Firefall" notes, a blackly funny in-universe lecture on resurrecting sociopathic vampirism (PDF - prev.), and a rigorously-cited (and spoiler-laden) reference section, tomorrow will see the release of
Norbert Wiener: The Eccentric Genius Whose Time May Have Finally Come (Again) - "The most direct reason for Wiener's fall to relative obscurity was the breakthrough of a young mathematician and engineer named Claude Shannon." [more inside]
Monsanto Is Going Organic in a Quest for the Perfect Veggie - "The lettuce, peppers, and broccoli—plus a melon and an onion, with a watermelon soon to follow—aren't genetically modified at all. Monsanto created all these veggies using good old-fashioned crossbreeding, the same technology that farmers have been using to optimize crops for millennia. That doesn't mean they are low tech, exactly. Stark's division is drawing on Monsanto's accumulated scientific know-how to create vegetables that have all the advantages of genetically modified organisms without any of the Frankenfoods ick factor." [more inside]
Take a stroll through French artist Vincent Fournier‘s [previously] gallery of animal photographs, and you’re likely to come across some creatures you’ve never seen before. Like, for instance, a jellyfish that is capable of electronically transmitting data across the Abyssal depths of the ocean. Or, perhaps, a scorpion that can perform semi-automated surgery on humans. “These creatures come from the future—an imagined future, based loosely on current research on synthetic biology and genetic engineering,” says Fournier, of his project Post-Natural History, a series of digitally-altered photos of animals that do not yet exist. “The idea is that these are living species, reprogrammed by mankind to better fit our environment as well as to adapt to new human desires.”
Recently Emily Graslie, of the fantastic natural history tumblr and youtube series TheBrainScoop, was asked a question about whether she had personally experienced sexism in her field. Her response is fucking amazing.
Inside is her goldmine of awesome female science educators online with channels that focus on Science Technology Engineering and Math. My work day is fucked.[more inside]
What do 3D printing, jelly, liver transplants, chainmail, dental fillings, ferrofluids, and the Six Million Dollar man have to tell us about our future? Materials scientist and engineer Mark Miodownik lets us know in this Royal Institution lecture.
seaQuest: what if we could learn to live on/underneath the oceans (or in orbit)? [previously(er)] [more inside]
Defense contractor takes break from F-35 JSF, finds a way to eliminate 99% of the energy cost of desalination. Lockheed-Martin has developed a way to craft sheets of carbon a single atom thick, which can filter the salt (and just about anything else) from water with a tiny fraction of the energy required by current processes. "Lockheed officials see other applications for Perforene as well, from dialysis in healthcare to cleaning chemicals from the water used in hydraulic fracturing, or "fracking," of oil and gas wells." Previously.
State of the Species: Will the unprecedented success of Homo sapiens lead to an unavoidable downfall? [Via]
On November 22, 2011, TEDxBrussels held an all day event whose theme was: "A Day in the Deep Future." Speakers were asked to try and contemplate what life will be like for mankind in 50 years. Overview. [more inside]
Using a 3-D petri dish, Researchers at Brown University and Women & Infants Hospital of Rhode Island have built a completely functional artificial human ovary that will allow doctors to harvest immature human egg cells (oocytes) and grow them into mature, ready-to-be-fertilized human eggs outside the body. (In vitro) The advance could eventually help preserve fertility for women facing chemotherapy or other medical treatments that may be destructive to ovarian folliculogenesis. Press Release. Article link. (paywall) [more inside]
Researchers at MIT and in Korea have developed a new, efficient desalinization nanotechnology that could theoretically lead to small, portable units powered by solar cells or batteries, yet deliver enough potable fresh water from seawater to supply the needs of a family or small village. As an added bonus, the system would simultaneously remove many contaminants, viruses and bacteria. MIT Press Release. Abstract and Supplementary Information from Nature Nanotechnology. (pdf) [more inside]
Juan Enriquez: Tech evolution will eclipse the financial crisis. "Even as mega-banks topple, Juan Enriquez says the big reboot is yet to come. But don't look for it on your ballot -- or in the stock exchange. It'll come from science labs, and it promises keener bodies and minds. Our kids are going to be ... different."
Scientists Repurpose Adult Cells - "Scientists have transformed one type of fully developed adult cell directly into another inside a living animal, a startling advance that could lead to cures for a variety of illnesses and sidestep the political and ethical quagmires associated with embryonic stem cell research." [nature abstract, nature writeup, audio announcement]
Worried about the state of biodiversity? Why not make some of your own? Moore’s law is all over biotechnology right now. Can the hackers be far behind? MIT's Drew Endy doesn’t think so. Ready to get started? You might already have some of the tools that you will need. Plans for others are available on the web. All you need now are some parts.
'Race' graphically illustrated - "most Europeans" vs. Ashkenazim (previously; see also IQ & Gladwell, viz. ;) [more inside]
The first Transhuman Conference On the Law of Transhuman Persons: Whether or not you believe humans are set to evolve into gods, or AI is destined to achieve self-awareness the idea of the Transhuman is a thought provoking concept. Philosophers have debated the nature of the self, of the human for millennia. Is it time to start drafting new laws to govern all possible sentient beings on this planet? or is it all just a science of fiction? a comfortable humanist illusion?
THE ULTIMATE SELF LINK: MY BRAIN. Use this excellent little MRI program to open .hdr 3d-scan files. Endless, disturbing fun.
Human Evolution Will the next significant steps be biological, technical or both?